Potential and Therapeutic Roles of Diosmin in Human Diseases
Biomedicines, 2022 Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade.
Etimad Huwait, Mohammad Mobashir
exaly +5 more sources
Antiviral potential of diosmin against influenza A virus [PDF]
Scientific ReportsInfluenza poses a global health threat. With drug-resistant strains emerging, there is an urgent need for effective antiviral drugs. This study explores antiviral potential of flavonoids against influenza A virus (IAV) and their mechanism of action.
Umarqayum AbuBakar +8 more
doaj +4 more sources
Plant metabolite diosmin as the therapeutic agent in human diseases
Current Research in Pharmacology and Drug Discovery, 2022 Plant-derived flavonoids have been the focus of research for many years mainly in the last decade owing to their therapeutic properties. So far, about 4000 flavonoids have been identified from plants and diosmin (a flavone glycoside) is one of them ...
Syed Akhtar Husain +2 more
exaly +3 more sources
Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats [PDF]
FoodsVascular aging is driven by a self-sustaining interplay between oxidative stress and chronic low-grade inflammation, collectively referred to as inflammaging.
Giulia Valdiserra +12 more
doaj +2 more sources
Molecules, 2018 Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids.
Nunziatina De Tommasi
exaly +3 more sources
Flavonoid Inhibition of Bacillus licheniformis LP-8 Lipase: In Vitro and In Silico Insights Into Anti-Obesity Potential. [PDF]
ChemistryOpenBacillus licheniformis LP‐8, isolated from hot spring, produced lipase using waste frying oil. Flavonoids inhibited enzyme activity, confirmed by reduced activity assays. Molecular docking revealed hydrogen‐bond interactions within the lipase active site.
Bayrak S, Omeroglu MA, Senol H.
europepmc +2 more sources
Interaction of diosmetin, diosmin and diosmetin-7-O-glucoside with human erythrocytes, their model membrane, hemoglobin and redox-active metal ions [PDF]
Frontiers in Molecular BiosciencesDiosmin, a flavonoid with documented vascular-protective properties, together with the closely related compounds diosmetin and diosmetin-7-O-glucoside, has not previously been subjected to a systematic comparative biophysical characterization.
Teresa Kaźmierczak +5 more
doaj +2 more sources
Effect of Diosmin on Selected Parameters of Oxygen Homeostasis
International Journal of Molecular Sciences, 2023 Chronic venous disease (CVD) is a condition characterized by functional disturbances in the microcirculation of the superficial and deep veins, affecting up to 30% of the global population. Diosmin, a phlebotropic drug, is commonly used in the treatment of CVD, and its beneficial effects have been described in numerous clinical studies.
Bartosz J. Płachno +2 more
exaly +5 more sources
Diosmin Administration Slightly Counteracted the Changes in Bone Mechanical Properties Induced by Experimental Type 1 Diabetes in Rats [PDF]
PharmaceuticalsBackground: There is interest in substances of plant origin that may have health-promoting effects regarding diabetes and its complications, including increased risk of fractures.
Kacper Grzywnowicz +6 more
doaj +2 more sources
Natural Product Communications, 2013 Diosmin is a naturally occurring flavone glycoside used in the treatment of venous diseases. In this review, we present the clinical aspects of the use of diosmin preparations in venous stasis, hemorrheologic disorders and vein wall remodeling.
Michał Woźniak +2 more
exaly +2 more sources