Results 1 to 10 of about 4,823 (154)

Plant metabolite diosmin as the therapeutic agent in human diseases

Current Research in Pharmacology and Drug Discovery, 2022
Plant-derived flavonoids have been the focus of research for many years mainly in the last decade owing to their therapeutic properties. So far, about 4000 flavonoids have been identified from plants and diosmin (a flavone glycoside) is one of them ...
Saad Mustafa, Mohammad Aasif Khan, Jogendra Singh Pawar   +2 more
exaly   +3 more sources

Potential and Therapeutic Roles of Diosmin in Human Diseases

Biomedicines, 2022
Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade.
Etimad Huwait, Mohammad Mobashir
exaly   +3 more sources

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +4 more sources

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +4 more sources

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers

Molecules, 2018
Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids.
, Nunziatina De Tommasi
exaly   +3 more sources

Diosmin Administration Slightly Counteracted the Changes in Bone Mechanical Properties Induced by Experimental Type 1 Diabetes in Rats [PDF]

Pharmaceuticals
Background: There is interest in substances of plant origin that may have health-promoting effects regarding diabetes and its complications, including increased risk of fractures.
Kacper Grzywnowicz, Piotr Londzin, Sylwia Klasik-Ciszewska, Weronika Borymska, Maria Zych, Ilona Kaczmarczyk-Żebrowska, Joanna Folwarczna   +6 more
doaj   +2 more sources

Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures [PDF]

Frontiers in Pharmacology
BackgroundOvarian Hyper-stimulation Syndrome (OHSS) is the main iatrogenic problem linked to ovarian stimulation with reproductive medications. Increased vascular permeability is considered the cause of OHSS.
Aya M. Abdallah, Amal K. Hussien, Sumaiah J. Alarfaj, Thanaa A. Elmasry, Thanaa A. Elmasry, Marwa Kamal, Hatem Sarhan, Mohammed H. Mosbeh, Eman Mohamed Sadek   +8 more
doaj   +2 more sources

Antiviral potential of diosmin against influenza A virus [PDF]

Scientific Reports
Influenza poses a global health threat. With drug-resistant strains emerging, there is an urgent need for effective antiviral drugs. This study explores antiviral potential of flavonoids against influenza A virus (IAV) and their mechanism of action.
Umarqayum AbuBakar, Zhao Xuan Low, Muhammad Zhafran Mohd Aris, Rafidah Lani, Syafiq Asnawi Zainal Abidin, Muhammad-Redha Abdullah-Zawawi, Pouya Hassandarvish, Saiful Anuar Karsani, Jasmine Elanie Khairat   +8 more
doaj   +2 more sources

Tailored biosynthesis of diosmin through reconstitution of the flavonoid pathway in Nicotiana benthamiana [PDF]

Frontiers in Plant Science
The flavonoid diosmin (diosmetin 7-O-rutinoside) is used as a therapeutic agent for disorders of the blood vessels such as hemorrhoids and varicose veins. Diosmin is commercially produced using semi-synthetic methods involving the oxidation of hesperidin,
Hyo Lee, Sangkyu Park, Saet Buyl Lee, Jaeeun Song, Tae-Hwan Kim, Beom-Gi Kim   +5 more
doaj   +2 more sources

Diosmin – Isolation Techniques, Determination in Plant Material and Pharmaceutical Formulations, and Clinical Use

Natural Product Communications, 2013
Diosmin is a naturally occurring flavone glycoside used in the treatment of venous diseases. In this review, we present the clinical aspects of the use of diosmin preparations in venous stasis, hemorrheologic disorders and vein wall remodeling.
Michal Wozniak, Marcin Feldo, Janusz Kocki   +2 more
exaly   +2 more sources