Results 1 to 10 of about 2,468 (112)

Plant metabolite diosmin as the therapeutic agent in human diseases

Current Research in Pharmacology and Drug Discovery, 2022
Plant-derived flavonoids have been the focus of research for many years mainly in the last decade owing to their therapeutic properties. So far, about 4000 flavonoids have been identified from plants and diosmin (a flavone glycoside) is one of them ...
Syed Akhtar Husain, Saad Mustafa, Jogendra Singh Pawar   +2 more
exaly   +3 more sources

Potential and Therapeutic Roles of Diosmin in Human Diseases

Biomedicines, 2022
Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade.
Etimad Huwait, Mohammad Mobashir, Mobashir Mohammad   +2 more
exaly   +3 more sources

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers

Molecules, 2018
Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids.
, Nunziatina De Tommasi, De Tommasi Nunziatina   +2 more
exaly   +3 more sources

Diosmin Administration Slightly Counteracted the Changes in Bone Mechanical Properties Induced by Experimental Type 1 Diabetes in Rats [PDF]

Pharmaceuticals
Background: There is interest in substances of plant origin that may have health-promoting effects regarding diabetes and its complications, including increased risk of fractures.
Kacper Grzywnowicz, Piotr Londzin, Sylwia Klasik-Ciszewska, Weronika Borymska, Maria Zych, Ilona Kaczmarczyk-Żebrowska, Joanna Folwarczna   +6 more
doaj   +2 more sources

Antiviral potential of diosmin against influenza A virus [PDF]

Scientific Reports
Influenza poses a global health threat. With drug-resistant strains emerging, there is an urgent need for effective antiviral drugs. This study explores antiviral potential of flavonoids against influenza A virus (IAV) and their mechanism of action.
Umarqayum AbuBakar, Zhao Xuan Low, Muhammad Zhafran Mohd Aris, Rafidah Lani, Syafiq Asnawi Zainal Abidin, Muhammad-Redha Abdullah-Zawawi, Pouya Hassandarvish, Saiful Anuar Karsani, Jasmine Elanie Khairat   +8 more
doaj   +2 more sources

Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures [PDF]

Frontiers in Pharmacology
BackgroundOvarian Hyper-stimulation Syndrome (OHSS) is the main iatrogenic problem linked to ovarian stimulation with reproductive medications. Increased vascular permeability is considered the cause of OHSS.
Aya M. Abdallah, Amal K. Hussien, Sumaiah J. Alarfaj, Thanaa A. Elmasry, Thanaa A. Elmasry, Marwa Kamal, Hatem Sarhan, Mohammed H. Mosbeh, Eman Mohamed Sadek   +8 more
doaj   +2 more sources

Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination

Food Chemistry: X
Diosmin is a flavonoid derived from plants, possessing anti-inflammatory, antioxidant, antidiabetic, neuroprotective and cardiovascular protective properties. However, diosmin has low solubility in water, leading to low bioavailability. In this study, we
Xiao Guan, Hongwei Cao, Hongdong Song
exaly   +3 more sources

Diosmin – Isolation Techniques, Determination in Plant Material and Pharmaceutical Formulations, and Clinical Use

Natural Product Communications, 2013
Diosmin is a naturally occurring flavone glycoside used in the treatment of venous diseases. In this review, we present the clinical aspects of the use of diosmin preparations in venous stasis, hemorrheologic disorders and vein wall remodeling.
Michał Wozniak, Marcin Feldo, Janusz Kocki   +2 more
exaly   +2 more sources

Qualitative and quantitative analysis of diosmin content of hyssop (Hyssopus officinalis) in response to salinity stress

Heliyon, 2021
Hyssop (Hyssopus officinalis L.) is a perennial subshrub, which is distributed across the eastern Mediterranean region to central Asia. One of the most important bioactive compounds of hyssop is diosmin, a flavone glycoside of diosmetin, with application
Zhaleh Soheilikhah, Masoud Modarresi, Naser Karimi, Ali Movafeghi   +3 more
doaj   +1 more source

Analysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach

BMC Complementary Medicine and Therapies, 2023
Background Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and antifibrotic activities.
Wen-Man Zhao, Zhi-Juan Wang, Rui Shi, Yuyu Zhu, Xun-Liang Li, De-Guang Wang   +5 more
doaj   +1 more source