Cisplatin (CP) is a platinum compound of the alkylating agent class that is used for the treatment of various types of cancer. However, CP treatments in cancer patients are accountable for nephrotoxicity, as it is a major adverse effect.
Tarique Anwer +10 more
doaj +1 more source
Flavonoid diosmetin increases ATP levels in kidney cells and relieves ATP depleting effect of ochratoxin A [PDF]
Diosmetin (DIOS) is a flavone aglycone commonly occurring in citrus species and olive leaves, in addition it is one of the active ingredients of some medications.
Antus, Csenge +8 more
core +1 more source
Prevention of intraocular pressure elevation with oleuropein rich diet in rabbits, during the general anaesthesia [PDF]
BACKGROUND: Oleuropein is known to have anti-oxidant and anti-inflammatory effects. An important aim of anesthetic management in ocular surgery is to keep the intraocular pressure under control. Studies have researched a variety of prophylactic materials
Betül Altınışık +6 more
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Phenolic composition, in vitro antioxidant effects and tyrosinase inhibitory activity of three Algerian Mentha species: M. spicata (L.), M. pulegium (L.) and M. rotundifolia (L.) Huds (Lamiaceae) [PDF]
International audienceThe leaves of three Mentha species harvested in Algeria, Mentha spicata L. (MS), Mentha pulegium L. (MP) and Mentha rotundifolia (L.) Huds (MR) were examined for their content in polyphenols and for some activities-linked biological
Brahmi, Fatiha +8 more
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Citrus phenylpropanoids and defence against pathogens. Part I: Metabolic profiling in elicited fruits [PDF]
Penicillium spp. are among the major postharvest pathogens of citrus fruit. Induction of natural resistance in fruits constitutes one of the alternatives to chemical fungicides.
Ballester Frutos, Ana Rosa +4 more
core +1 more source
In view of the established antidiabetic properties of zinc, the present study was aimed at evaluating the hypoglycemic properties of a new zinc-diosmin complex in high fat diet fed-low dose streptozotocin induced experimental type 2 diabetes in rats ...
Veerasamy Gopalakrishnan +2 more
doaj +1 more source
Diosmin is a flavonoid derived from plants, possessing anti-inflammatory, antioxidant, antidiabetic, neuroprotective and cardiovascular protective properties. However, diosmin has low solubility in water, leading to low bioavailability. In this study, we
Sen Li +8 more
doaj +1 more source
Diosmin Enhances the Anti-migration Activity of Curcumin Analog PGV-1 on Colorectal Cancer Cells
BACKGROUND: Diosmin enhances the cytotoxicity of Pentagamavunone-1 (PGV-1) in cancer cells. PGV-1 and diosmin are predicted to target several matrix metalloproteinases (MMPs) in metastatic cancer, including colorectal cancer, but the anti-migration ...
Muthi Ikawati +4 more
doaj +1 more source
Michèle Cazaubon,1 Jean-Patrick Benigni,2 Marcio Steinbruch,3 Violaine Jabbour,4 Christelle Gouhier-Kodas4 1Private Vascular Specialist, Paris, France; 2Pedagogical Support Office, Faculty of Medicine Pitié-Salpétrière, Sorbonne University, Paris, France;
Cazaubon M +4 more
doaj
Solidification of nanosuspensions for the production of solid oral dosage forms and inhalable dry powders [PDF]
INTRODUCTION: Nanosuspensions combine the advantages of nanotherapeutics (e.g. increased dissolution rate and saturation solubility) with ease of commercialisation.
Buckton, G +3 more
core +1 more source

