Results 31 to 40 of about 2,537 (174)

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

BMC Complementary Medicine and Therapies
Background Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure.
Wen-Man Zhao, Xun-Liang Li, Yuyu Zhu, Rui Shi, Zhi-Juan Wang, Jian-Ping Xiao, De-Guang Wang   +6 more
doaj   +1 more source

Diosmin alleviates retinal edema by protecting the blood-retinal barrier and reducing retinal vascular permeability during ischemia/reperfusion injury.

PLoS ONE, 2013
Background and purposeRetinal swelling, leading to irreversible visual impairment, is an important early complication in retinal ischemia/reperfusion (I/R) injury.
Nianting Tong, Zhenzhen Zhang, Wei Zhang, Yating Qiu, Yuanyuan Gong, Lili Yin, Qinghua Qiu, Xingwei Wu   +7 more
doaj   +1 more source

Arginine‐Enriched Oral Nutritional Supplement as an Adjunct to Standard of Care in the Treatment of Recalcitrant Venous Leg Ulcers

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Venous leg ulcers (VLUs) are common, difficult to heal, and prone to recurrence. Malnutrition and impaired nitric‐oxide–dependent microcirculation may contribute to recalcitrance. Arginine‐enriched oral nutritional supplements (ONS) improve healing in other wound types, but data in VLUs is limited.
Wen Wei Kiang, Brittany Ng, Li Zhang, Enming Yong, Tina Peiting Lai   +4 more
wiley   +1 more source

Diosmin and Bromelain Stimulate Glutathione and Total Thiols Production in Red Blood Cells

Molecules, 2023
Diosmin and bromelain are bioactive compounds of plant origin with proven beneficial effects on the human cardiovascular system. We found that diosmin and bromelain slightly reduced total carbonyls levels and had no effect on TBARS levels, as well as ...
Lukasz Gwozdzinski, Joanna Bernasinska-Slomczewska, Anna Wiktorowska-Owczarek, Edward Kowalczyk, Anna Pieniazek   +4 more
doaj   +1 more source

Successful Treatment of Pigmented Purpuric Dermatoses With Abrocitinib: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Pigmented Purpuric Dermatoses (PPD) are chronic conditions often resistant to standard treatments, creating a need for new therapies, particularly for those suffering from severe itching. This report details a patient with a year of refractory lower‐extremity PPD who failed multiple oral and topical treatments.
Yuping Zhang, Xiji Lu, Chen Li
wiley   +1 more source

Diosmin versus cabergoline for prevention of ovarian hyperstimulation syndrome

Middle East Fertility Society Journal, 2017
Background: OHSS (Ovarian Hyperstimulation Syndrome) is the most serious iatrogenic complication of ovulation induction. The pathophysiology of OHSS is characterised by increased capillary permeability, leading to leakage of fluid from the vascular ...
Ahmed Samy Saad, Khalid Abd Aziz Mohamed
doaj   +1 more source

Valorization of Banana Biomass: Nutritional and Phytochemical Insights With Applications in Food and Allied Industries

eFood, Volume 7, Issue 2, April 2026.
Composition, biological activity and food application of banana biomass. ABSTRACT The global banana processing industry generates substantial organic waste in the form of peels, leaves, stems, and flowers, posing both environmental challenges and opportunities for valorization within a circular economy framework.
Bushra Iram Fatima, Saeed Akhtar, Muhammad Zulqarnain Khan, Muhammad Qamar, Tariq Ismail, Wisha Saeed, Elham Assadpour, Tuba Esatbeyoglu, Seid Mahdi Jafari   +8 more
wiley   +1 more source

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Antioxidant Potential of Diosmin and Diosmetin against Oxidative Stress in Endothelial Cells

Molecules, 2022
Phlebotropic flavonoids, including diosmin and its aglycone diosmetin, are natural polyphenols widely used in the prevention and treatment of chronic venous insufficiency (CVI).
Magdalena Wójciak, Marcin Feldo, Grzegorz Borowski, Tomasz Kubrak, Bartosz J. Płachno, Ireneusz Sowa   +5 more
doaj   +1 more source