Results 31 to 40 of about 3,363 (198)

Diosmin/hesperidin: a cooperating tandem, or is diosmin crucial and hesperidin an inactive ingredient only? [PDF]

Vnitřní lékařství, 2020
With the advent of novel monocomponent venoactive drugs containing the flavonoid diosmin, the need has arisen to answer the question of therapeutic equivalence of the widely used micronized purified flavonoid fraction (MPFF) contained in Detralex and of the currently introduced monocomponent venoactive drugs.
Debora, Karetová, Josef, Suchopár, Jan, Bultas   +2 more
openaire   +2 more sources

Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study

Antioxidants, 2021
Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the modulatory effects of diosmin against doxorubicin-induced hepatotoxicity in Male Wistar rats.
Abdullah F. AlAsmari, Metab Alharbi, Faleh Alqahtani, Fawaz Alasmari, Mohammed AlSwayyed, Sami I. Alzarea, Ibrahim A. Al-Alallah, Adel Alghamdi, Hassan M. Hakami, Meshal K. Alyousef, Youssef Sari, Nemat Ali   +11 more
doaj   +1 more source

Assessment of Platelet Reactivity and Inflammatory Markers in Coronary Artery Bypass Graft Patients Treated with Acetylsalicylic Acid with Flavonoid Supplementation

Molecules, 2021
The recommended pharmacological therapy for patients with coronary artery disease (CAD) treated by coronary artery bypass grafting (CABG) is acetylsalicylic acid (ASA).
Aldona Siennicka, Magdalena Kłysz, Monika Adamska, Kornel Chełstowski, Andrzej Biskupski, Maria Jastrzębska   +5 more
doaj   +1 more source

Nephroprotective Effect of Diosmin against Cisplatin-Induced Kidney Damage by Modulating IL-1β, IL-6, TNFα and Renal Oxidative Damage

Molecules, 2023
Cisplatin (CP) is a platinum compound of the alkylating agent class that is used for the treatment of various types of cancer. However, CP treatments in cancer patients are accountable for nephrotoxicity, as it is a major adverse effect.
Tarique Anwer, Saeed Alshahrani, Ahmad M. H. Somaili, Abdullah H. Khubrani, Rayan A. Ahmed, Abdulmajeed M. Jali, Ayed Alshamrani, Hina Rashid, Yousra Nomeir, Mohammad Khalid, Mohammad Firoz Alam   +10 more
doaj   +1 more source

The affinity of tigecycline to human serum albumin in the presence of diosmin [PDF]

, 2021
Tigecycline (TGC) is a new intravenous antibiotic with broad-spectrum effect against many drug-resistant organisms. Further, TGC is new class representer of antibacterial agents, named glycylcyclines.
Stefan Stojanović, Stojanović, Stefan, Mrkalić, Emina, Jelic, Ratomir, Sovrlic, Miroslav, Ratomir Jelić, Miroslav Sovrlić, Ćendić Serafinović, Marina, Marina Ćendić Serafinović, Emina Mrkalić   +9 more
core   +1 more source

Synthesis, Spectral Characterization, and Biochemical Evaluation of Antidiabetic Properties of a New Zinc-Diosmin Complex Studied in High Fat Diet Fed-Low Dose Streptozotocin Induced Experimental Type 2 Diabetes in Rats

Biochemistry Research International, 2015
In view of the established antidiabetic properties of zinc, the present study was aimed at evaluating the hypoglycemic properties of a new zinc-diosmin complex in high fat diet fed-low dose streptozotocin induced experimental type 2 diabetes in rats ...
Veerasamy Gopalakrishnan, Subramanian Iyyam Pillai, Sorimuthu Pillai Subramanian   +2 more
doaj   +1 more source

Total Antioxidant Activity, and Hesperidin, Diosmin, Eriocitrin and Quercetin Contents of Various Lemon Juices [PDF]

, 2014
Purpose: To investigate 38 natural and 62 branded lemon juices for their total antioxidant activities and flavonoid content.Methods: The ferric reducing antioxidant power was applied to evaluation of antioxidant.
Sadeghi, N, Mousavi, SM, Moghaddam, G, Oveisi, MR, Jannat, B, Hajimahmoodi, M   +5 more
core   +1 more source

Diosmin ameliorates LPS-induced depression-like behaviors in mice: Inhibition of inflammation and oxidative stress in the prefrontal cortex

Brain Research Bulletin
Diosmin is a flavone glycoside with a confirmed therapeutic effectiveness on the chronic venous disorders. In this paper, the classical mouse depression model induced by LPS was established to explore the effect of Diosmin on depression.
Jingwei Zhao, Mingming Zhang, Huamin Zhang, Ying Wang, Bingyu Chen, Jing Shao   +5 more
doaj   +1 more source

ANALISIS KANDUNGAN DIOSMIN TANAMAN SELEDRI PADA BERBAGAI MEDIA TUMBUH [PDF]

, 2010
The celery plant well known as herbs especially because of celery’s odor and it also have a lot of positive impact to health, for example antidiuretic, antiplasmodic and antiinflammatory.
Syabana, Mohamad Ana, Surahadikusuma, Elly, PK, Edi Jauhari   +2 more
core   +1 more source

Is There a Difference in the Clinical Efficacy of Diosmin and Micronized Purified Flavonoid Fraction for the Treatment of Chronic Venous Disorders? Review of Available Evidence

Vascular Health and Risk Management, 2021
Michèle Cazaubon,1 Jean-Patrick Benigni,2 Marcio Steinbruch,3 Violaine Jabbour,4 Christelle Gouhier-Kodas4 1Private Vascular Specialist, Paris, France; 2Pedagogical Support Office, Faculty of Medicine Pitié-Salpétrière, Sorbonne University, Paris, France;
Cazaubon M, Benigni JP, Steinbruch M, Jabbour V, Gouhier-Kodas C   +4 more
doaj