Results 41 to 50 of about 2,537 (174)

The Herbal Pair Daphniphyllum calycinum–Polygonum hydropiper Alleviates Gastric Mucosal Injury via Regulating Autophagy and Targeting the TLR4/NF‐κB/NLRP3 Pathway

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
The schematic diagram illustrated the proposed mechanism of DCPH in mouse macrophages. DCPH promotes autophagy to suppress the TLR4/NF‐κB/NLRP3 pathway and M1 polarization, thereby attenuating cellular oxidative stress and inflammation. ABSTRACT Gastric mucosal injury refers to the pathological changes characterized by congestion, edema, bleeding and ...
Yunyun Zhi, Keli Zhou, Xueqing Huang, Yonghui Li, Ye Zhu, Yiqiang Xie, Shouzhong Ren   +6 more
wiley   +1 more source

The Benefits of the Citrus Flavonoid Diosmin on Human Retinal Pigment Epithelial Cells under High-Glucose Conditions

Molecules, 2017
We investigate diosmin for its effect on the ARPE-19 human retinal pigment epithelial cells exposed to high glucose, a model of diabetic retinopathy (DR). After incubation for 4 days with a normal (5 mmol/L) concentration of D-glucose, ARPE-19 cells were
Wayne Young Liu, Shorong-Shii Liou, Tang-Yao Hong, I-Min Liu   +3 more
doaj   +1 more source

Toward Sustainability in Cardiac Tissue Engineering: Electrospun Polyurethane Scaffolds Functionalized With Lemon‐Derived Bioactives

Global Challenges, Volume 10, Issue 4, April 2026.
Electrospun polyurethane scaffolds biofunctionalized with lemon extract exhibit refined nanofibre morphology, enhanced hydrophilicity, improved mechanical strength, and superior hemocompatibility. The PU/lemon scaffold demonstrates antimicrobial activity and increased fibroblast proliferation, highlighting its potential as a sustainable multifunctional
Mohan Prasath Mani, Saravana Kumar Jaganathan   +1 more
wiley   +1 more source

Quantitative Determination of Diosmin in Tablets by Infrared and Raman Spectroscopy

Molecules, 2022
Diosmin is widely used in the treatment of chronic venous diseases and hemorrhoids. Based on Raman and infrared reflection spectra of powdered tablets in the mid- and near-infrared regions and results of reference high-performance liquid chromatographic ...
Sonia Pielorz, Magdalena Węglińska, Sylwester Mazurek, Roman Szostak   +3 more
doaj   +1 more source

Upcycling orange by‐product: phenolic bioaccessibility and technological features of jelly candies enriched with hydroalcoholic and enzymatic extracts

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3773-3785, April 2026.
Abstract BACKGROUND Phenolic extracts are recognized for their health‐promoting properties, although some physicochemical characteristics limit their food applications. The present study aimed to valorize orange juice by‐products through enzymatic and hydroalcoholic extraction to obtain flavonoid ingredients and to evaluate their application in pectin ...
Bárbara Morandi Lepaus, Nathalia Almeida Costa, Gabriela de Matuoka e Chiocchetti, Paula de Paula Menezes Barbosa, Marise Bonifácio Queiroz, Izabela Dutra Alvim, Juliana Alves Macedo, Gabriela Alves Macedo   +7 more
wiley   +1 more source

Effects of Diosmin on Vascular Leakage and Inflammation in a Mouse Model of Venous Obstruction

Frontiers in Nutrition, 2022
At present, iliac vein compression syndrome (IVCS) plagues countless people, posing a significant economic and social burden. The progress of current IVCS-related research is slow owing to the limitations of animal models.
Junjie Zou, Dongping Yuan, Jin Yang, Yun Yu   +3 more
doaj   +1 more source

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

ChemistryOpen, Volume 15, Issue 4, April 2026.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair, Katim Alaoui   +10 more
wiley   +1 more source

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, Volume 13, Issue 17, 23 March 2026.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Ketamine-induced behavioral perturbations, redox imbalances, and neurotransmitter deficits in mice: The preventive and reversal neuromodulatory potential of diosmin as an antipsychotic

Brain Disorders
Schizophrenia is a major neuropsychiatric disorder associated with neurochemical perturbations characterized by behavioral abnormalities, for which effective treatment remains elusive. The current study investigated the neurotransmitter modulatory effect
Aya-Ebi Okubo Eneni, Benneth Ben-Azu, Abayomi Mayowa Ajayi, Adegbuyi Oladele Aderibibge   +3 more
doaj   +1 more source