Results 41 to 50 of about 3,363 (198)

Effects of paraprobiotic Lactobacillus acidophilus LA‐5 on PANoptosis, oxidative stress and inflammation in acetic acid‐induced ulcerative colitis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Ulcerative colitis (UC) is a relapsing inflammatory bowel disease characterised by oxidative stress, inflammation and regulated cell death of the colonic mucosa. Because live probiotics may cause bacteraemia and sepsis in immunocompromised hosts, non‐viable (paraprobiotic) alternatives have attracted interest.
Adem Yavaş, Ezgi Özkıran, Ecem Akan
wiley   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

ZIF‐8‐Based Solid‐Phase Extraction Coupled With Derivative UV‐Vis Spectrophotometry for Rapid Simultaneous Determination of Hesperidin and Naringin in Citrus Peels

Chemistry–Methods, Volume 6, Issue 10, October 2026.
This graphical abstract illustrates the synthesis and application of ZIF‐8 as a solid‐phase extraction sorbent for the simultaneous determination of hesperidin and naringin in citrus peels. ZIF‐8 was synthesized from zinc nitrate hexahydrate and 2‐methylimidazole, followed by mixing, centrifugation, and drying.
Akram Sadat Nabavi, Sayed Mehdi Ghoreishi, Fateme Tajabadi   +2 more
wiley   +1 more source

A Randomized Controlled Trial Evaluating the Effects of Diosmin in the Treatment of Radicular Pain

, 2017
Diosmin has been widely used to treat patients with vascular pain for its potent anti-inflammatory and analgesic effects. To evaluate the therapeutic effects of Diosmin in the treatment of radicular pain, we conducted an investigator-initiated ...
Yinhe Wang, Li, Yishan,, Cao, Y,, Wang, Y, Ye, Lei,, Yang Cao, Hongfei Shi, Cao, Yang,, Shi, H, Fang, Xin,, Lei Ye, Shi, Hongfei,, Li, Y, Xin Fang, Ye, L, Wang, Yinhe,, Yishan Li, Fang, X,   +17 more
core   +1 more source

Diosmin Promotes Myogenesis via Activating the Akt/FOXO1 Pathway to Facilitate the Proliferation of C2C12 Myoblasts

, 2023
Our previous study with artificial intelligence (AI)-assisted screening found that diosmin, a natural flavonoid extracted from citrus, may affect myoblast proliferation and differentiation.
Xiangfei Ma (8549733), Honglin Liu (108352), Xuan Zhang (56049), Jie Chen (5892), Ming Shen (156685), Zhaojun Liu (238486), Hongmin Li (50993), Dingding Zhang (217863)   +7 more
core   +1 more source

Novel Diterpenoids From Salvia rosmarinus Reveal a Compound With Antiproliferative and Antioxidant Activities

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Four novel diterpenoids were isolated from Salvia rosmarinus (rosemary), together with nine known compounds. ECD calculations were employed to establish the absolute configuration of diterpenoids 1 and 2. The 18‐hydroxycarnosol (1) was evaluated as antiproliferative (SRB assay) and antioxidant (DPPH and TBARS), showing promising results.
Diana Pérez‐Juanchi, Celia Bustos‐Brito, Ma. Teresa Ramírez‐Apan, Antonio Nieto‐Camacho, Leovigildo Quijano, Baldomero Esquivel   +5 more
wiley   +1 more source

Diosmin alleviates retinal edema by protecting the blood-retinal barrier and reducing retinal vascular permeability during ischemia/reperfusion injury.

PLoS ONE, 2013
Background and purposeRetinal swelling, leading to irreversible visual impairment, is an important early complication in retinal ischemia/reperfusion (I/R) injury.
Nianting Tong, Zhenzhen Zhang, Wei Zhang, Yating Qiu, Yuanyuan Gong, Lili Yin, Qinghua Qiu, Xingwei Wu   +7 more
doaj   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

BMC Complementary Medicine and Therapies
Background Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure.
Wen-Man Zhao, Xun-Liang Li, Yuyu Zhu, Rui Shi, Zhi-Juan Wang, Jian-Ping Xiao, De-Guang Wang   +6 more
doaj   +1 more source

Diosmin and Bromelain Stimulate Glutathione and Total Thiols Production in Red Blood Cells

Molecules, 2023
Diosmin and bromelain are bioactive compounds of plant origin with proven beneficial effects on the human cardiovascular system. We found that diosmin and bromelain slightly reduced total carbonyls levels and had no effect on TBARS levels, as well as ...
Lukasz Gwozdzinski, Joanna Bernasinska-Slomczewska, Anna Wiktorowska-Owczarek, Edward Kowalczyk, Anna Pieniazek   +4 more
doaj   +1 more source