Results 61 to 70 of about 3,363 (198)

Potential of Chinese Mandarin Peel and Leaf (Agricultural Byproducts) as Candidate Ingredients for Functional Foods and Feeds

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Mandarin peel (with higher contents of the key bioactive compounds hesperidin, nobiletin, and tangeretin) and leaf (with richer chemical diversity) are potential candidate ingredients for functional foods and feeds. The key bioactive compounds (hesperidin, nobiletin, and tangeretin) have optimal conditions for daily consumption, achieved through three ...
Jing Chen, Qinggui Lei, Boyong Chen, Chao Zhang, Zhijian Zeng, Guodong Chen, Zhengming Qian, Wenhao Wang   +7 more
wiley   +1 more source

Development and Evaluation of Diosmin Nanoparticle-Loaded Oral Tablets for Enhancing Dissolution and Oral Bioavailability

Bulletin of Pharmaceutical Sciences. Assiut University
Diosmin is a natural polyphenolic compound that is characterized by poor aqueous solubility and low oral bioavailability. This study aimed to develop immediate-release tablets containing PEG-stabilized diosmin nanoparticles to enhance dissolution and ...
Abdelsattar El-Banna, Khaled Ismail, Wael Abdullah, Gamal Zayed   +3 more
doaj   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

A Spectrophotometric Method for Diosmin Determination [PDF]

The Open Chemical and Biomedical Methods Journal, 2010
A rapid and sensitive spectrophotometric method for the determination of diosmin (D) has been developed. The method is based on the reaction of D with 4-aminoantipyrine (AAP) in the presence of hexacyanoferrate (III) (HCF) in an alkaline medium and subsequent formation of a purple coloured product havingmax at 524.5 nm.
openaire   +1 more source

Ketamine-induced behavioral perturbations, redox imbalances, and neurotransmitter deficits in mice: The preventive and reversal neuromodulatory potential of diosmin as an antipsychotic

Brain Disorders
Schizophrenia is a major neuropsychiatric disorder associated with neurochemical perturbations characterized by behavioral abnormalities, for which effective treatment remains elusive. The current study investigated the neurotransmitter modulatory effect
Aya-Ebi Okubo Eneni, Benneth Ben-Azu, Abayomi Mayowa Ajayi, Adegbuyi Oladele Aderibibge   +3 more
doaj   +1 more source

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Arginine‐Enriched Oral Nutritional Supplement as an Adjunct to Standard of Care in the Treatment of Recalcitrant Venous Leg Ulcers

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Venous leg ulcers (VLUs) are common, difficult to heal, and prone to recurrence. Malnutrition and impaired nitric‐oxide–dependent microcirculation may contribute to recalcitrance. Arginine‐enriched oral nutritional supplements (ONS) improve healing in other wound types, but data in VLUs is limited.
Wen Wei Kiang, Brittany Ng, Li Zhang, Enming Yong, Tina Peiting Lai   +4 more
wiley   +1 more source

GASTROPROTECTIVE PROPERTIES OF METAPROT AND DIOSMIN

Reviews on Clinical Pharmacology and Drug Therapy, 2012
Intragastric administration of acetylsalicylic acid induces development of NSAID-gastropathy in animals. The number of ulcers and the total area of erosive injury in the mucous membrane are studied. Antioxidants/antihypoxants metaprot in a daily dose of 50 mg/kg and diosmin in a daily dose of 100 mg/kg render gastroprotective action.
Nadezhda Olegovna Kryukova, Vasily Egorovich Novikov, Alexandr Sergeevich Novikov, Petr Dmitrievich Shabanov   +3 more
openaire   +1 more source

Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is the most common liver-related metabolic disorder in the world, with a global prevalence of 25%.
Reza Afarin, Negar Dinarvand, Bahar Jaberian Asl, Ghazal Orak, Elham Shakerian, Fatemeh Bineshfar, Akram Ahangarpour   +6 more
doaj   +1 more source

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source