Results 61 to 70 of about 4,892 (216)

Upcycling orange by‐product: phenolic bioaccessibility and technological features of jelly candies enriched with hydroalcoholic and enzymatic extracts

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3773-3785, April 2026.
Abstract BACKGROUND Phenolic extracts are recognized for their health‐promoting properties, although some physicochemical characteristics limit their food applications. The present study aimed to valorize orange juice by‐products through enzymatic and hydroalcoholic extraction to obtain flavonoid ingredients and to evaluate their application in pectin ...
Bárbara Morandi Lepaus, Nathalia Almeida Costa, Gabriela de Matuoka e Chiocchetti, Paula de Paula Menezes Barbosa, Marise Bonifácio Queiroz, Izabela Dutra Alvim, Juliana Alves Macedo, Gabriela Alves Macedo   +7 more
wiley   +1 more source

A combination of diosmin, hesperidin, and ruscogenin

Formosan Journal of Surgery, 2022
Background: Phlebotonics are made of plant extracts and synthetic compounds. Although their mechanism of action is not completely clear, they are associated with an increase in venous tone and decreased capillary permeability. The aim of this paper was to assess the efficacy of Diosmin 500mg, Esperidine 90mg, Ruscogenin 100mg ...
Romano L., Nervini A., Stia S., Schietroma M., Giuliani A.   +4 more
openaire   +2 more sources

The Benefits of the Citrus Flavonoid Diosmin on Human Retinal Pigment Epithelial Cells under High-Glucose Conditions

Molecules, 2017
We investigate diosmin for its effect on the ARPE-19 human retinal pigment epithelial cells exposed to high glucose, a model of diabetic retinopathy (DR). After incubation for 4 days with a normal (5 mmol/L) concentration of D-glucose, ARPE-19 cells were
Wayne Young Liu, Shorong-Shii Liou, Tang-Yao Hong, I-Min Liu   +3 more
doaj   +1 more source

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

ChemistryOpen, Volume 15, Issue 4, April 2026.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair, Katim Alaoui   +10 more
wiley   +1 more source

Toxicity of a dental adhesive compared with ionizing radiation and zoledronic acid [PDF]

, 2015
Background: To determine the toxicity of aqueous dilutions of a universal self-priming dental adhesive (DA) and comparing these with those elicited by exposure to ionizing radiation (IR), Zoledronic acid (Z) treatment and the synergic effects of the ...
Achel, Daniel Giyngiri, Alcaraz Baños, Miguel, Canteras Jordana, Manuel, Fondevilla Soler, Adriana, García Cruz, Emilio, Olivares Rueda, Amparo   +5 more
core   +5 more sources

Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum

Plant Biotechnology Journal, Volume 24, Issue 4, Page 1936-1949, April 2026.
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang, Qingwen Wu, Wenjing Shi, Yinai Deng, Ruoting Zhan, Dongming Ma   +5 more
wiley   +1 more source

GASTROPROTECTIVE PROPERTIES OF METAPROT AND DIOSMIN

Reviews on Clinical Pharmacology and Drug Therapy, 2012
Intragastric administration of acetylsalicylic acid induces development of NSAID-gastropathy in animals. The number of ulcers and the total area of erosive injury in the mucous membrane are studied. Antioxidants/antihypoxants metaprot in a daily dose of 50 mg/kg and diosmin in a daily dose of 100 mg/kg render gastroprotective action.
Nadezhda Olegovna Kryukova, Vasily Egorovich Novikov, Alexandr Sergeevich Novikov, Petr Dmitrievich Shabanov   +3 more
openaire   +1 more source

THE MANAGEMENT OF POSTOPERATIVE PAIN AFTER HEMORRHOIDECTOMY: ANALYSIS OF THREE METHODICS [PDF]

, 2012
Postoperative pain is one of the most common and disabling complications following hemorrhoidectomy. This study divided a total of 90 patients, undergone Milligan and Morgan hemorrhoidectomy, in three groups of 30 patient: Group A, undergone internal ...
ACCARDO, F, DAMIANO, Giuseppe, DE LUCA, S, FICARELLA, Silvia, GIOVIALE, Maria Concetta, LO MONTE, Attilio Ignazio, PALUMBO, Vincenzo Davide, RANDAZZO, Stefania, SPINELLI, Gabriele, TOMASELLO, Giovanni   +9 more
core  

Drug-Induced Anaphylaxis Survey in Portuguese Allergy Departments [PDF]

, 2014
BACKGROUND AND OBJECTIVE: Drug-induced anaphylaxis is an unpredictable and potentially fatal adverse drug reaction. The aim of this study was to identify the causes of drug-induced anaphylaxis in Portugal.
Botelho, C, Castro, E, et al, Faria, E, Gaspar, A, Morais-Almeida, M, Portuguese Society of Allergology and Clinical Immunology, Rodrigues-Cernadas, J   +7 more
core   +2 more sources

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, Volume 13, Issue 17, 23 March 2026.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source