Results 81 to 90 of about 3,363 (198)

Pharmacokinetic Profile of μSMIN Plus™, a new Micronized Diosmin Formulation, after Oral Administration in Rats

open access: yesNatural Product Communications, 2015
Diosmin is a naturally occurring flavonoid present in citrus fruits and other plants belonging to the Rutaceae family. It is used for the treatment of chronic venous insufficiency (CVI) for its pheblotonic and vaso-active properties, safety and ...
Rosario Russo   +5 more
doaj   +1 more source

Hepatoprotective effects of diosmin: a narrative review

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology
Abstract Liver diseases represent a formidable global health threat. Hesperidin, a flavonoid found in citrus fruits, is the source of diosmin (DS). The in vivo and in vitro investigations of the pharmacological effects of DS reveal that it exhibits tremendous beneficial effects, such as fighting against inflammation, oxidative stress, and ...
Hassanein, Emad H. M.   +3 more
openaire   +2 more sources

Luteolin and diosmin/diosmetin as novel STAT3 inhibitors for treating autism [PDF]

open access: yes, 2014
The present invention includes methods for the treatment of autoimmune disorders such as autism, schizophrenia, and type 1 diabetes. Flavonoids, luteolin, diosmin, and diosmin\u27s aglycone form, diosmetin, were found to inhibit activation ...
Tan, Jun   +2 more
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Nephroprotective Potential of Ginger, Diosmin, and Their Combination on Induced Diabetic Nephropathy in a Rat Model: Light and Electron Microscopic Observations [PDF]

open access: yesThe Egyptian Journal of Histology
Introduction: Hyperglycemia is a chronic illness that is associated with diabetes. Patients with diabetes have been found to have many alterations in their renal functioning.
Samar Gad   +4 more
doaj   +1 more source

Hyssopus officinalis L. the source of diosmin as the therapeutic agent in different diseases [PDF]

open access: yes
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroduction. The species Hyssopus officinalis L. is known over the years as a medicinal plant based on volatile oils.
Golub, Alexandrina
core   +1 more source

Rat abdominal epigastrik flebinde diosmin + hesperidinin iskemi reperfüzyon hasarına etkisi

open access: yes, 2015
Giriş ve Amaç: İskemi reperfüzyon(İ-R) hasarı rekonstrüktif cerrahide flep kayıplarının en önemli sebeplerinden biridir. İ-R hasarına bağlı flep kayıplarını azaltmak amacıyla birçok farmakolojik ajan kullanılmış fakat henüz net bir tedavi protokolü ...
SELÇUK YAZAN
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The Effect of Diosmin Hesperidin on Intestinal Ischaemia — Reperfusion Injury

open access: yesActa Chirurgica Belgica, 2004
The effect of Diosmin Hesperidin on intestinal ischaemia reperfusion injury was evaluated in an experimental model in rats.Forty Spraque-Dawley rats were divided into 4 groups of (n = 10) (sham, sham + Diosmin Hesperidin, Reperfusion, Reperfusion + Diosmin Hesperidin).
Pehlivan, Mevlüt   +6 more
openaire   +4 more sources

Sepsis-induced acute kidney injury: kidney protection effects by antioxidants

open access: yesRevista Brasileira de Enfermagem
Objective: To evaluate the antioxidant action of N-acetylcysteine and diosmin-hesperidin in an experimental model of sepsis-induced acute kidney injury in rats. Methods: The study used 20 Wistar adult male rats divided into the following groups: control
Carolina Ferreira Vasco   +3 more
doaj   +1 more source

Effects of diosmine-hesperidine on experimental colonic anastomosis

open access: yesBratislava Medical Journal, 2012
Our goal was to determine the effects of a diosmine-hesperidine combination on wound healing in a rat model of colonic anastomosis.In this study, 20 Wistar Albino female rats were randomized into four experimental groups containing five rats in each group.
Kilicoglu, S.S.   +10 more
openaire   +4 more sources

PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K–Akt–MDM2 signaling suppression

open access: yes, 2012
[[abstract]]Hepatocellular carcinoma is a common type of cancer with poor prognosis. This study examines the in vitro and in vivo mechanisms of diosmin on human hepato-cellular carcinoma HA22T cell proliferation inhibition.
Tran Duc Dung;Cecilia Hsuan Day;Truong Viet Binh;Chih-Hsueh Lin;Hsi-Hsien Hsu;Cheng-Chuan Su;Yueh-Min Lin;Fuu-Jen Tsai;Wei-Wen Kuo;Li-Mien Chen;Chih-Yang Huang
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