Results 81 to 90 of about 4,892 (216)

Is Nonmicronized Diosmin 600 mg as Effective as Micronized Diosmin 900 mg plus Hesperidin 100 mg on Chronic Venous Disease Symptoms? Results of a Noninferiority Study

International Journal of Vascular Medicine, 2020
Background. Phlebotonics have beneficial effects on some symptoms related to chronic venous disease (CVD) of the lower limbs. The most commonly used one is diosmin, available in a pure semisynthetic form or as a micronized purified flavonoid fraction ...
Marcio Steinbruch, Carlos Nunes, Romualdo Gama, Renato Kaufman, Gustavo Gama, Mendel Suchmacher Neto, Rafael Nigri, Natasha Cytrynbaum, Lisa Brauer Oliveira, Isabelle Bertaina, François Verrière, Mauro Geller   +11 more
doaj   +1 more source

Варикозная болезнь нижних конечностей, особенности у лиц старших возрастных групп [PDF]

, 2012
Представлены эпидемиология, методы диагностики и лечения варикозной болезни нижних конечностей. Возраст – единственный главный идентифицируемый фактор риска. Заболеваемость варикозной болезнью увеличивается линейно с возрастом.
Горелик, С .Г., Литынский, А. В., Поляков, П. И.   +2 more
core  

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

The FEBS Journal, Volume 293, Issue 5, Page 1386-1399, March 2026.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima, Sayako Shimomura, Mayuka Wakabayashi, Wei Qi Loh, Harumi Ando, Haruka Sei, Hiroyuki Hattori, Didik Huswo Utomo, Masaki Kita, Asuka Inoue, Koji Uchida, Takahiro Shibata   +11 more
wiley   +1 more source

Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway

Medicina
Background and Objectives: This study aimed to investigate the protective effect of diosmin and hesperidin in diabetic neuropathy using a rat model, focusing on their impact on nerve regeneration through the fibroblast growth factor 21 (FGF21) and ...
Birzat Emre Gölboyu, Mümin Alper Erdoğan, Mehmet Ali Çoşar, Ezgi Balıkoğlu, Oytun Erbaş   +4 more
doaj   +1 more source

Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]

, 2012
A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe, Boxall, Alistair B.A., Bruemer, Janine, Fussell, Richard, Greenwood, Richard, Monteiro, Sara C., Williams, Richard J.   +6 more
core  

Ποσοτικοποίηση των μορίων εσπεριδίνης, εσπεριτίνης, ναρινγίνης και ναρινγενίνης σε πλάσμα [PDF]

, 2013
Στο παρόν παραδοτέο περιγράφεται η μέθοδος ποιοτικού και ποσοτικού προσδιορισμoύ των φυσικών αντιοξειδωτικών Εσπεριδίνης, Εσπερετίνης, Ναρινγίνης και Ναρινγενίνης στην εκτροφή των αγροτικών ζώων για παραγωγή προϊόντων ποιότητας με τη χρήση υγρής ...
Γεωπονικό Πανεπιστήμιο Αθηνών - Εργαστήριο Ζωοτεχνίας
core   +1 more source

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats [PDF]

, 2017
Simvastatin is a lipid-lowering agent used to treat hypercholesterolemia and to reduce the risk of heart disease. This study scrutinized the beneficial effects of simvastatin on experimental diabetic cardiomyopathy (DCM), pointing to the role of ...
Al-Ajmi, Hanaa N., Al-Amin, Maha A., Al-Rasheed, Nawal M., Al-Rasheed, Nouf M., Hasan, Iman H., Mahmoud, Ayman M., Mohamad, Raeesa A.   +6 more
core   +3 more sources

Exploitation of the Antibacterial Activity of Micromeria graeca L. Extracts From Northern Morocco

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Among the various extraction techniques investigated, the methanolic ultrasound‐assisted extract (MGME‐UAE) of Micromeria graeca L exhibited the strongest bactericidal effect, selectively inhibiting Proteus mirabilis (inhibition zone 12.7 ± 0.6 mm; MIC = 6.25 mg/mL).
Houda Chtibi, Kaoutar Harboul, Taoufiq Benali, Aziz Bouymajane, Roberto Laganà Vinci, Francesco Cacciola, Luigi Mondello, Khalil Hammani   +7 more
wiley   +1 more source

Hepatoprotective effects of diosmin: a narrative review

Naunyn-Schmiedeberg's Archives of Pharmacology
Abstract Liver diseases represent a formidable global health threat. Hesperidin, a flavonoid found in citrus fruits, is the source of diosmin (DS). The in vivo and in vitro investigations of the pharmacological effects of DS reveal that it exhibits tremendous beneficial effects, such as fighting against inflammation, oxidative stress, and ...
Hassanein, Emad H. M., Althagafy, Hanan S., Baraka, Mohammad A., Amin, Haitham   +3 more
openaire   +2 more sources

Nephroprotective Potential of Ginger, Diosmin, and Their Combination on Induced Diabetic Nephropathy in a Rat Model: Light and Electron Microscopic Observations [PDF]

The Egyptian Journal of Histology
Introduction: Hyperglycemia is a chronic illness that is associated with diabetes. Patients with diabetes have been found to have many alterations in their renal functioning.
Samar Gad, Samia Manawy, Manar Foda, Dania Mohammed, Kamal Kamal   +4 more
doaj   +1 more source