Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion
Разработка и регистрация лекарственных средствIntroduction. The extremely unfavorable physical, chemical and functional properties of diosmin, a component of a number of popular phleboprotective drugs, cause an increased therapeutic dosage of the active pharmaceutical ingredient (API) in the dosage ...
A. A. Danilova +5 more
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Effect of Diosmin on Lipopolysaccharide-induced Neuroinflammation and Cognitive Impairment in Mice
Ibom Medical JournalContext: Neuroinflammation has been linked to some neurobehavioral alterations including cognitive and memory impairment which are prominent features of many neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease.
Adeoluwa GA +7 more
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Diagram depicting the ameliorative actions of diosmin in ethanol-induced gastric injury.
, 2015 Diagram depicting the ameliorative actions of diosmin in ethanol-induced gastric injury.
Hany H. Arab (364331) +4 more
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The effect of the flavonoid diosmin, grape seed extract and red wine on the pulmonary metastatic B16F10 melanoma [PDF]
, 2005 Objective: To study the effect of different phenolic compounds and red wine on pulmonary metastatic melanoma. Methods: Swiss mice were inoculated with 5x105 melanocytes B16F10 and given oral doses of diosmin, grape seed extract (GSE) and red ...
Vicente García, Vicente +7 more
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The effects of diosmin on aflatoxin-induced liver and kidney damage
, 2017 Aflatoxin is among the natural toxins that cause serious side effects on living things. Diosmin is also one of the compounds with broad pharmacological effects. In this study, the effects on the oxidant/antioxidant system of 50 mg/kg body weight/day dose
TEKELİ, Muhammet Yasin +11 more
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The Flavonoids Hesperidin and Diosmin: Adjuvant Therapy for Obesity
Journal of the Pakistan Medical AssociationThe flavonoids are polyphenolic plant products,characterized by a 15-carbon skeleton which includes twobenzene rings. Two active flavonoids, diosmin andhesperidin, are used as venotonic and vasculoprotectiveagents in clinical practice. They are indicated for themanagement of varicose veins, chronic venousinsufficiency and haemorrhoids.
Sanjay, Kalra +3 more
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Neuroprotective Effect of Diosmin on Arsenic Trioxide Induced Neurotoxicity in Albino Wistar Rats. [PDF]
, 2014 The present study the term ‘neurotoxic’ is used to describe a substance, condition or state that damages the nervous system and/or brain, usually by killing neurons.
Gangireddy, K
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Evaluation of the efficacy of diosmin and chrysin against tau-fluvalinate exposure in rats
Tau-fluvalinate is a type 2 pyrethroid insecticide. Diosmin and chrysin are flavonoids with antioxidant and anti-apoptotic effects. Role of diosmin and chrysin against infavorable toxic effects caused by tau-fluvalinate and the underlying mechanisms of ...
Gedik, Didem, ERASLAN, GÖKHAN
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, 2015 Diosmin is a naturally occurring flavonoid present in citrus fruits and other plants belonging to the Rutaceae family. It is used for the treatment of chronic venous insufficiency (CVI) for its pheblotonic and vaso-active properties, safety and ...
SEVERINO, LORELLA +5 more
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Pharmaceutical forms and therapeutic indications of diosmin-based phytotherapeutical products [PDF]
INTRODUCERE. Diosmina este un compus din clasa flavonoidelor, care prezintă interes mare pentru domeniul farmaceutic, datorită proprietăţilor venotonice, antioxidante, hepato-protectoare, antidiabetice, anticancerigene, antimicrobiene etc.
Calalb, Tatiana, Golub, Alexandrina
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