Results 71 to 80 of about 4,892 (216)

Pretraživanje tradicionalnih europskih ljekovitih biljaka na inhibiciju acetilkolinesteraze i butirilkolinesteraze [PDF]

, 2010
Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of Alzheimer’s disease (AD) to enhance central cholinergic transmission. On the other hand, butyrylcholinesterase (BuChE) inhibitors were reported to produce significant
A. Adsersen, A. Ferreira, A. Marston, Agnieszka Kuciun, Anna Kiss, E. Teuscher, G. Ellman, G. Romussi, H. Wolf, M. Wichtl, N. Perry, Natalia Wszelaki, P. Bradley, R. Houghton, R. Lane, S. Kang, T. Mennini   +16 more
core   +3 more sources

Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone‐Based Derivatives

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira, Simona Distinto, Carlos Fernandes, Erica Sanna, Rita Meleddu, Marco Gaspari, Filippo Cottiglia, Alessia Onali, Andrea Angeli, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran, Elias Maccioni   +13 more
wiley   +1 more source

Ketamine-induced behavioral perturbations, redox imbalances, and neurotransmitter deficits in mice: The preventive and reversal neuromodulatory potential of diosmin as an antipsychotic

Brain Disorders
Schizophrenia is a major neuropsychiatric disorder associated with neurochemical perturbations characterized by behavioral abnormalities, for which effective treatment remains elusive. The current study investigated the neurotransmitter modulatory effect
Aya-Ebi Okubo Eneni, Benneth Ben-Azu, Abayomi Mayowa Ajayi, Adegbuyi Oladele Aderibibge   +3 more
doaj   +1 more source

Recent Insights on Synthesis, Stability, and Complexities of Water‐in‐Oil Pickering Emulsion: From Theory to Applications

Food Frontiers, Volume 7, Issue 2, March 2026.
It provides a conceeptual framework of the core components required for w/o PE development and various internal and external factors determining the emulsion stabilization. It also emphasizes the emerging application of w/o PE in diverse industrial use such as encapsulation and delivery, packaging, food, biomedical, etc.
Bibha Mishra A., Vidisha Tomer
wiley   +1 more source

Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is the most common liver-related metabolic disorder in the world, with a global prevalence of 25%.
Reza Afarin, Negar Dinarvand, Bahar Jaberian Asl, Ghazal Orak, Elham Shakerian, Fatemeh Bineshfar, Akram Ahangarpour   +6 more
doaj   +1 more source

Identification of Citri Reticulatae Pericarpium (Chenpi) From Different Cultivars via LC–MS/MS and UPLC Coupled With Multivariate Chemometrics Analysis

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
A UPLC‐based quantitative analysis combined with multivariate chemometric methods differentiated seven Citri Reticulatae Pericarpium cultivars based on significant variations in nine flavonoids. Chemometric analysis effectively separated the seven cultivars, and hesperetin was identified as a unique marker for C. reticulata “Chachi”.
Danlin Lin, Jinju Zhang, Mingqi Chen, Chuchu Zhong, Hui Cao, Zhiguo Ma, Menghua Wu, Ying Zhang   +7 more
wiley   +1 more source

Evaluation of the Protective Effect of Diosmin in Attenuating Methotrexate-induced Lung Fibrosis in the Adult Albino Rat [PDF]

Al-Azhar International Medical Journal, 2000
Background: Methotrexate (MXT) is a folic acid analog used in treatment of systemic inflammatory diseases such assystemic lupus, rheumatoid arthritis, psoriasis, and many malignancies, including lung and breast cancer.
doaj   +1 more source

Fluorescence spectroscopic evaluation of the interactions of quercetin, isorhamnetin, and quercetin-3'-sulfate with different albumins [PDF]

, 2018
Quercetin is one of the most commonly occurring flavonoids in nature. Although, quercetin and its metabolites express negligible fluorescence, the albumin-bound form of quercetin has a strong fluorescence property.
Boda, Gabriella, Kroon, Paul A., Kunsági-Máté, Sándor, Lemli, Beáta, Needs, Paul W., Poór, Miklós   +5 more
core   +1 more source

High‐throughput transcriptome mining and in silico screening reveal saccharide feeding stimulants for Cydia pomonella larvae

New Plant Protection, Volume 3, Issue 1, March 2026.
We identified and characterized the gustatory and ionotropic receptors of Cydia pomonella using transcriptomics and in silico approaches, linking candidate sugar receptors to larval feeding attraction. Functional assays and behavioral tests highlighted isoquercitrin as a key feeding stimulant, providing a foundation for olfactory‐ and taste‐based pest ...
Chenyun Ding, Zaiyuan Li, Qiang Wu, Bo Liu, Fanghao Wan, Cong Huang, Rui Tang   +6 more
wiley   +1 more source

Revisiting diosmin for their potential biological properties and applications

Carbohydrate Polymer Technologies and Applications
Diosmin is a well-known naturally occurring flavonoid that is used to treat diseased veins and chronic blood vessel insufficiency. A comprehensive investigation conducted recently has revealed that diosmin has a wide range of medical specialty properties,
Mani Rajasekar, Pavithra Baskaran, Jennita Mary, Meenamigai Sivakumar, Masilamani Selvam   +4 more
doaj   +1 more source