Results 11 to 20 of about 3,363 (198)

Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures [PDF]

open access: yesFrontiers in Pharmacology
BackgroundOvarian Hyper-stimulation Syndrome (OHSS) is the main iatrogenic problem linked to ovarian stimulation with reproductive medications. Increased vascular permeability is considered the cause of OHSS.
Aya M. Abdallah   +8 more
doaj   +4 more sources

Diosmin induces caspase-dependent apoptosis in human glioblastoma cells [PDF]

open access: yesAnais da Academia Brasileira de Ciências, 2019
: Diosmin is a flavone glycoside clinically used as the main component of Daflon for the treatment of venous diseases. Several studies demonstrated that this natural compound can induce apoptosis in different tumors.
JULIANA M. SOARES   +7 more
doaj   +4 more sources

Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis

open access: yesMicromachines, 2021
Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification.
Iulia Gabriela David   +5 more
doaj   +2 more sources

Analysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach

open access: yesBMC Complementary Medicine and Therapies, 2023
Background Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and antifibrotic activities.
Wen-Man Zhao   +5 more
doaj   +2 more sources

Comparative Assessment of Quality Requirements for Medicinal Products Containing Diosmin [PDF]

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2023
Currently, there is an increase in preand post-approval testing of medicinal products containing diosmin and hence a need to unify approaches to standardisation of this group of pharmaceuticals. Moreover, the State Pharmacopoeia of the Russian Federation
N. P. Antonova   +6 more
doaj   +2 more sources

Tailored biosynthesis of diosmin through reconstitution of the flavonoid pathway in Nicotiana benthamiana [PDF]

open access: yesFrontiers in Plant Science
The flavonoid diosmin (diosmetin 7-O-rutinoside) is used as a therapeutic agent for disorders of the blood vessels such as hemorrhoids and varicose veins. Diosmin is commercially produced using semi-synthetic methods involving the oxidation of hesperidin,
Hyo Lee   +5 more
doaj   +2 more sources

Revisiting diosmin for their potential biological properties and applications

open access: yesCarbohydrate Polymer Technologies and Applications
Diosmin is a well-known naturally occurring flavonoid that is used to treat diseased veins and chronic blood vessel insufficiency. A comprehensive investigation conducted recently has revealed that diosmin has a wide range of medical specialty properties,
Mani Rajasekar   +4 more
doaj   +2 more sources

Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination

open access: yesFood Chemistry: X
Diosmin is a flavonoid derived from plants, possessing anti-inflammatory, antioxidant, antidiabetic, neuroprotective and cardiovascular protective properties. However, diosmin has low solubility in water, leading to low bioavailability. In this study, we
Wanqing Cao, Hongwei Cao, Tong Guan
exaly   +3 more sources

Is Nonmicronized Diosmin 600 mg as Effective as Micronized Diosmin 900 mg plus Hesperidin 100 mg on Chronic Venous Disease Symptoms? Results of a Noninferiority Study

open access: yesInternational Journal of Vascular Medicine, 2020
Background. Phlebotonics have beneficial effects on some symptoms related to chronic venous disease (CVD) of the lower limbs. The most commonly used one is diosmin, available in a pure semisynthetic form or as a micronized purified flavonoid fraction ...
Marcio Steinbruch   +11 more
doaj   +2 more sources

Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway

open access: yesMedicina
Background and Objectives: This study aimed to investigate the protective effect of diosmin and hesperidin in diabetic neuropathy using a rat model, focusing on their impact on nerve regeneration through the fibroblast growth factor 21 (FGF21) and ...
Birzat Emre Gölboyu   +4 more
doaj   +2 more sources

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