Results 151 to 160 of about 159,120 (369)

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Edemas in chronic lower extremity venous insufficiency: Clinical manifestations, medical and surgical treatments

Терапевтический архив, 2013
The review presents data on the causes and pathogenesis of lower extremity (LE) edemas with special emphasis on the edemas occurring in chronic LE venous insufficiency.
G N Gorokhovskaia, V L Iun
doaj  

High‐Efficiency Carriers’ Separation Strategy Based Ultrasmall‐Bandgap CuWO4 Sono‐Enhances GSH Antagonism for Cuproptosis Cascade Immunotherapy

Advanced Science, EarlyView.
This study prepares copper tungstate (CuWO4, CWO) nanoparticles for synergistic sono‐enhanced cuproptosis‐based cancer therapy. With an ultrasmall bandgap (1.71 eV), CWO facilitates efficient charge carrier separation under ultrasound, enhancing the generation of reactive oxygen species and the controlled release of Cu2+ ions cascade amplify oxidative ...
Lichao Zhu, Zhisheng Guo, Yu Luo, Haiyan Huang, Kexin Zhang, Bingbing Duan, Renmiao Peng, Haochen Yao, Chao Liang, Kaiyang Wang   +9 more
wiley   +1 more source

News in Pathogenesis of Chronic Venous Insufficiency

Acta Medica Martiniana, 2016
This review article is concentrating on the news in the pathophysiology of chronic venous insufficiency (CVD). Despite ongoing progress in understanding the molecular aspects of CVD the exact mechanism of its development remains unclear.
Mazuchova J, Pec M, Halasova E, Valentova V, Sarlinova M, Mazuch J, Zelnik S   +6 more
doaj   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Investigation of Chronic Venous Insufficiency [PDF]

, 2000
Andrew Nicolaides
openalex   +1 more source

Network meta-analysis to compare VenaSeal with other superficial venous therapies for chronic venous insufficiency.

Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2020
R. Kolluri, Janice Chung, Sue Kim, Nibir Nath, B. B. Bhalla, Tarun Jain, J. Zygmunt, A. Davies   +7 more
semanticscholar   +1 more source

Understanding and applying compression therapy [PDF]

, 2014
Atkin L, Shirlow
Atkin, Leanne, Shirlow, K.
core  

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Target selection for surgical intervention in severe chronic venous insufficiency: Comparison of duplex scanning and phlebography [PDF]

, 2000
Ralph G. DePalma, Donna L. Kowallek, Thomas C. Barcia, H.Treat Cafferata   +3 more
openalex   +1 more source