ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Local and Systemic Endothelial Damage in Patients with CEAP C2 Chronic Venous Insufficiency: Role of Mesoglycan. [PDF]
Santoliquido A +8 more
europepmc +1 more source
Seasonal variation in swelling of lower extremity edema in patients with chronic venous insufficiency. [PDF]
Santa Cruz M +5 more
europepmc +1 more source
Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics
Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park +7 more
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Chronic venous insufficiency increases postoperative complications after Mohs micrographic surgery for lower extremity nonmelanoma skin cancer: A propensity-matched retrospective cohort study. [PDF]
Talasila S +3 more
europepmc +1 more source
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng +6 more
wiley +1 more source
Analysis of the Combined Effects of a Novel Combination of Hypersmin, Pumpkin Seed and Amaranthus Extracts in an In Vitro Model of Chronic Venous Insufficiency. [PDF]
Ferrari S +4 more
europepmc +1 more source
Chronic Venous Insufficiency and Lymphedema With Papillomatosis Cutis Lymphostatica, Hyperkeratosis, and Skin Ulcers: A Case Report. [PDF]
Senanayake J +4 more
europepmc +1 more source
Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang +8 more
wiley +1 more source

