Results 191 to 200 of about 98,391 (335)

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

The phenotype of monocyte subtypes and expression of chemokine receptors in the Chronic Venous Insufficiency. [PDF]

Clinics (Sao Paulo)
Germano DB, Chiba LN, Ballerini APADC, Bussador do Amaral J, Shio MT, Alves JM, de Abreu DA, Nali LHDS, Fonseca FAH, Izar MC, Bachi ALL, França CN.   +11 more
europepmc   +1 more source

Effectiveness of Sclerotherapy to Cure Lower Limb Chronic Venous Insufficiency Grades 1-6: A Systematic Review and Meta-Analysis. [PDF]

Cureus, 2023
Dewi DAR, Arimuko A, Norawati L, Dewi RK, Wiraguna AAGP, Allatib A, Arkania N, Nadhira F, Wiliantari NM.   +8 more
europepmc   +1 more source

Limitations of VEINES QOL/SYM for discriminating chronic venous insufficiency severity

, 2019
Giane Amorim Ribeiro-Samora, Maria Luíza Vieira Carvalho, Regina Moura, Danielle Aparecida Gomes Pereira   +3 more
openalex   +1 more source

Spongiosolysis [PDF]

, 1987
Gilbert, P., Stief, Christian Georg
core   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Extensive Nodular Melanoma at the Site of Chronic Venous Insufficiency. [PDF]

Indian Dermatol Online J
Singh S, Poonia K, Kapatia G, Rana MK.
europepmc   +1 more source

Video-capillaroscopy, a promising tool for the clinical evaluation of patients with chronic venous insufficiency. [PDF]

Front Med (Lausanne), 2023
Carpentier PH, Trolliet C, Cornu-Thénard A, Chamberod R, Laurès J, Noilhetas J, Chauvin E.   +6 more
europepmc   +1 more source

Chronic Venous Insufficiency (CVI) with Ulcus Cruris [PDF]

, 2002
Matthias Augustin
openalex   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source