Results 251 to 260 of about 128,522 (343)

Real‐world population pharmacokinetics of tezacaftor‐ivacaftor in children with cystic fibrosis: The SYM‐CF study

British Journal of Clinical Pharmacology, EarlyView.
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk, Suzanne W. J. Terheggen‐Lagro, Eric G. Haarman, Hettie M. Janssens, Anke‐Hilse Maitland–van der Zee, E. Marleen Kemper, Ron A. A. Mathôt, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) research group   +7 more
wiley   +1 more source

Efficacy of complex decongestive therapy on venous flow, internal saphenous diameter, edema, fat mass of the limbs and quality of life in patients with chronic venous insufficiency: A randomized clinical trial. [PDF]

J Vasc Surg Venous Lymphat Disord
Martín Jiménez A, Bermejo Gil BM, Santos-Lozano A, Pinto-Fraga FJ, García Barroso C, Vittori LR, Fraino A, Menéndez Alegre H.   +7 more
europepmc   +1 more source

Comparing the Effectiveness of 1064 vs. 810 nm Wavelength Endovascular Laser for Chronic Venous Insufficiency (Varicose Veins)

, 2013
De-Yi Yu, Hung‐Chang Chen, Shu-Ying Chang, Yen-Chang Hsiao, Cheng‐Jen Chang   +4 more
openalex   +2 more sources

Effectiveness and safety of combining thiazides with loop diuretics vs. loop diuretics monotherapy in patients with acute decompensated heart failure: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). Methods In this retrospective study, adults hospitalized for ADHF and who received intravenous loop diuretics between January 2016 and March 2023 were enrolled.
Chia‐Chen Hsu, Hsien‐Chih Chiu, Ju‐Chieh Wung, Yueh‐Ching Chou, Yuh‐Lih Chang, Chian‐Ying Chou, Chin‐Chou Huang   +6 more
wiley   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

British Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl, Rod Hughes, Joachim Almquist, David Close, Jukka Mäenpää, Ulrika Tehler, Tina Jellesmark Jensen, Szilárd Nemes, Anne‐Kristina Mercier, Zala Jevnikar, Pablo Forte Soto, Dave Singh   +11 more
wiley   +1 more source

Various Therapies for Lymphedema and Chronic Venous Insufficiency, Including a Multimodal At-Home Nonpneumatic Compression Treatment. [PDF]

Adv Skin Wound Care
Barnhart H, Maldonado T, Rockson SG.
europepmc   +1 more source

Symptoms in patients with skin changes due to chronic venous insufficiency often lead to emergency care service: an Italian observational study

International Wound Journal, 2016
Michele Ruggiero, Raffaele Grande, A. Naso, Lucia Butrico, P. Rubino, Girolamo Domenico Placida, M. Cannistra', R. Serra   +7 more
semanticscholar   +1 more source

The Effect of α‐Mangostin on the Pharmacokinetic Profile of Tofacitinib in Rats Both In Vitro and In Vivo

Biopharmaceutics &Drug Disposition, EarlyView.
α‐mangostin (α‐MG) significantly affected tofacitinib metabolism by competing for the same site in CYP3A4. Co‐administration of these two medicines poses a potential herb–drug interaction. ABSTRACT This study investigated the effects of α‐mangostin (α‐MG) on the pharmacokinetics of tofacitinib in vitro and in vivo, aiming to recommend its appropriate ...
Jiange Yao, Zebei Lu, Quan Zhou, Abdullah Al Mamun, Yaru Shi, Shuanghu Wang, Ying Yao   +6 more
wiley   +1 more source

Widening participation in outward student mobility: Successes, challenges and opportunities

British Educational Research Journal, EarlyView.
Abstract This article utilises data obtained through evaluation processes at Northumbria University to contribute to the emerging discourse on widening participation and outward student mobility. The rationale behind the study stems from the significant financial and non‐financial benefits associated with higher education and the UK's ongoing efforts ...
Joseph Mellors, Alejandra Vicencio
wiley   +1 more source

Evaluation of the dynamic thiol/disulfide homeostasis in patients with chronic venous insufficiency. [PDF]

J Vasc Surg Venous Lymphat Disord
Muduroglu A, Velioglu Y, Celik H, Yuksel A, Aldemir M, Atasoy MS, Kilic AO, Cetintas D, Badem S, Cayir MC, Gok G, Bal C.   +11 more
europepmc   +1 more source