Results 51 to 60 of about 499,259 (311)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Chronic wound isolates and their minimum inhibitory concentrations against third generation cephalosporins at a tertiary hospital in Uganda

Scientific Reports, 2022
Globally, the burden of chronic wound infections is likely to increase due to the rising levels of bacterial resistance to antibiotics. In the United States of America alone, more than 6.5 million chronic wounds with evidence of bacterial infection are ...
Khalim Wangoye, James Mwesigye, Martin Tungotyo, Silvano Twinomujuni Samba   +3 more
doaj   +1 more source

The detection of wound infection by ion mobility chemical analysis [PDF]

, 2020
Surgical site infection represents a large burden of care in the National Health Service. Current methods for diagnosis include a subjective clinical assessment and wound swab culture that may take several days to return a result.
Bechar, Janak, Covington, James A., Daulton, Emma, Hardwicke, Joseph, Wicaksono, Alfian   +4 more
core   +1 more source

Implementing clinical process management of vascular wounds in a tertiary facility: Impact evaluation of a performance improvement project [PDF]

, 2017
BACKGROUND: Chronic vascular wounds have a significant economic and social impact on our society calling for allocation of a great deal of attention and resources.
Avruscio, Giampiero, Bordignon, Greta, Tocco-Tussardi, Ilaria, Vindigni, Vincenzo   +3 more
core   +2 more sources

Smart Wound Dressings for Diabetic Chronic Wounds [PDF]

Bioengineering, 2018
Given their severity and non-healing nature, diabetic chronic wounds are a significant concern to the 30.3 million Americans diagnosed with diabetes mellitus (2015). Peripheral arterial diseases, neuropathy, and infection contribute to the development of these wounds, which lead to an increased incidence of lower extremity amputations.
Gianino, Elizabeth, Miller, Craig, Gilmore, Jordon   +2 more
openaire   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Translational Challenges in Drug Therapy and Delivery Systems for Treating Chronic Lower Extremity Wounds

Pharmaceutics
Despite several promising preclinical studies performed over the past two decades, there remains a paucity of market-approved drugs to treat chronic lower extremity wounds in humans.
Danny Aljamal, Priya S. Iyengar, Tammy T. Nguyen   +2 more
doaj   +1 more source

Chronic wounds treated with cold atmospheric plasmajet versus best practice wound dressings: a multicenter, randomized, non-inferiority trial

Scientific Reports, 2022
The use of phase-adapted wound dressings represents best practice (BP) in chronic wound treatment. However, efficacy is often limited and associated care requirements are high.
R. Strohal, S. Dietrich, M. Mittlböck, G. Hämmerle   +3 more
doaj   +1 more source

High Levels of Oxidative Stress and Skin Microbiome are Critical for Initiation and Development of Chronic Wounds in Diabetic Mice. [PDF]

, 2019
A balanced redox state is critical for proper healing. Although human chronic wounds are characterized by high levels of oxidative stress (OS), whether OS levels are critical for chronic wound development is not known.
Borneman, James, Kim, Jane H, Lebig, Elyson Gavin D, Martins-Green, Manuela, Ruegger, Paul M, Tedesco, Amanda, Xu, Karen, Yang, Benjamin   +7 more
core  

The Debrisoft ® monofilament debridement pad for use in acute or chronic wounds: A NICE medical technology guidance [PDF]

, 2015
As part of its Medical Technology Evaluation Programme, the National Institute for Health and Care Excellence (NICE) invited a manufacturer to provide clinical and economic evidence for the evaluation of the Debrisoft ® monofilament debridement pad for ...
A Piaggesi, AW Goode, B Campbell, Catherine Meads, D Gray, D Williams, Eleonora Lovato, F Smith, I Michiels, J Edwards, J Stephen-Haynes, J White, JC Dumville, JC Dumville, JFP Posnett, JL Jensen, K Withers, Louise Longworth, M Bradley, M Doerler, MO Soares, P Raynor, PA D’Hemecourt, R Strohal, RG Brunner, S Bahr, S Johnson   +26 more
core   +2 more sources