Results 141 to 150 of about 237,116 (358)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

CHRONIC WOUNDS : RISK FACTORS AND EVIDENCE-BASED INTERVENTION

open access: yesJurnal Rekonstruksi dan Estetik
Highlights: • Identifies key risk factors for chronic wounds and the underexplored role of genetics and immune dysregulation in healing. • Explores advanced interventions like smart bandages and bioengineered skin, while addressing accessibility ...
Veronica Abebia Beginanta Pinem   +4 more
doaj   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Chronic Pseudomonas aeruginosa Biofilm Infection Impairs Murine S100A8/A9 and Neutrophil Effector Cytokines – Implications for Delayed Wound Closure? [PDF]

open access: bronze, 2017
Hannah Trøstrup   +7 more
openalex   +1 more source

Hyperbaric oxygen influences chronic wound healing – a cellular level review

open access: gold, 2021
Jiří Růžička   +4 more
openalex   +1 more source

Correction to: Application of Comfort Therapy under eCASH Concept in Acute and Chronic Wound Treatment [PDF]

open access: gold, 2023
Shuting Shi   +5 more
openalex   +1 more source

Home - About - Disclaimer - Privacy