Results 81 to 90 of about 121,354 (286)
Genital Skin Diseases and Their Expression in Sexual Functionality [PDF]
, 2015 Sexual functionality acts as an important function of the individual, acting both physically and mentally to create a state of well-being and permitting procreation.
Albu, Gabriela +3 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Brain SciencesBackground/Objectives: Patients with non-specific chronic neck pain (NSCNP) exhibit sensorimotor disturbances, with proprioception impairment considered an important aspect.
George A. Koumantakis +5 more
doaj +1 more source
Deep convolutional networks for automated detection of posterior-element fractures on spine CT
, 2016 Injuries of the spine, and its posterior elements in particular, are a common occurrence in trauma patients, with potentially devastating consequences.
Burns, Joseph E. +5 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Predicting subsequent contralateral slipped capital femoral epiphysis: an evidence-based approach. [PDF]
, 2020 PurposeThe purpose of this study was to identify risk factors for developing a subsequent contralateral slipped capital femoral epiphysis (SCFE) and provide a prediction score to quantify risk of subsequent slip at the time of initial presentation ...
Baldwin, Keith +4 more
core
Reconstitution of hepatitis B virus (HBV)-specific T cell responses with treatment of human immunodeficiency virus/HBV coinfection [PDF]
, 2003 Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus (HBV)-coinfected patients receiving highly active antiretroviral therapy (HAART).
Bertoletti, A +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
BMC Primary CareBackground Cardiovascular diseases are becoming more frequent throughout the world. Adherence to both pharmacological and non-pharmacological treatment, as well as lifestyles, is important for good management and control of the disease.
Álvaro Carbonell-Soliva +11 more
doaj +1 more source
Sclerotic disease, integrative diagnosis, chronic forms and treatment of diseases [PDF]
Саратовский научно-медицинский журнал, 2015 The aim of the article is to determine the importance of an integrative approach to identify and analyze the phases or stages of the example of chronic sclerotic disease (CSD). The proposed concept of CSD is to use the diagnostic methods before sclerotic
Kats Ya.A. +2 more
doaj