Results 41 to 50 of about 1,183 (121)

No Evidence for Seasonal Variations in Fatigue, Sleepiness and Insomnia Symptoms: Spring Fatigue Is a Cultural Phenomenon Rather Than a Seasonal Syndrome

Journal of Sleep Research, EarlyView.
ABSTRACT Although not as prominent as in other animals, humans also experience seasonal variations in sleep duration and circadian processes. These variations are likely primarily driven by changes in photoperiod length. Anecdotally, many people report experiencing fatigue and low energy levels, particularly during spring in Germany, Switzerland and ...
Christine Blume, Albrecht Vorster
wiley   +1 more source

Chronobiology and Chronotherapy of Osteoporosis

JBMR Plus, 2021
Physiological circadian (ie, 24‐hour) rhythms are critical for bone health. Animal studies have shown that genes involved in the intrinsic molecular clock demonstrate potent circadian expression patterns in bone and that genetic disruption of these clock
Elizabeth M Winter, Sander Kooijman, Natasha M Appelman‐Dijkstra, Onno C Meijer, Patrick CN Rensen, Maaike Schilperoort   +5 more
doaj   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3295-3304, April 2026.
Abstract Aims Little is known about how the alignment between daily behaviours, such as physical activity and eating, and chronotype relates to glucose metabolism. We investigated whether alignment of physical activity and meal timing with chronotype was associated with glycaemic parameters and with prediabetes or type 2 diabetes (T2DM).
Marvin Y. Chong, Joseph Henson, Martijn J. L. Bours, Hans Bosma, Bastiaan E. de Galan, Carla J. H. van der Kallen, Ree M. Meertens, Hans H. C. M. Savelberg, Miranda T. Schram, Matty P. Weijenberg, Thomas Yates, Annemarie Koster, Simone J. P. M. Eussen   +12 more
wiley   +1 more source

A Senolytic Strategy for Metabolic Health: Why the Endothelium Matters

iNew Medicine, EarlyView.
He Liang, Yu Wang, Yang Zhang, Xiaoqiang Tang   +3 more
wiley   +1 more source

Chronic Night Shift Is More Detrimental Than Chronic Light at Night on Circadian Rhythmicity and Metabolic Health in a Female Diurnal Rodent

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
To dissociate the effects induced by artificial indoor light at night from those induced by circadian desynchronization, females of the diurnal rodent, Arvicanthis ansorgei, were exposed to chronic indoor light at night (mimicking nightwork) or to chronic night shift (mimicking shiftwork).
Emma Grosjean, Stéphanie Dumont‐Kientzy, Illona‐Marie Bouleté, Dominique Ciocca, Sarahi Jaramillo‐Ortiz, Fabrice Bertile, Pierre Dehousse, Bertrand Ducos, Valérie Simonneaux, Etienne Challet   +9 more
wiley   +1 more source

Review of the monographi S.M. Chibisov, G.S. Katinas, M.V. Ragulskaya. “Biorhythms and cosmos: monitoring cosmobiospheric connections”

RUDN Journal of Medicine, 2014
The book presents the results, long-term monitoring of physiological parameters of the human body and heliophysical factors. The authors examine the history of the development of chronobiology from the antique times to our time, in more detail stopping ...
S A Shastun, S I Rapoport
doaj  

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Impact of Varying Sleep Pressure on Daytime Sleep Propensity in Healthy Young and Older Adults

Clocks & Sleep
Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals.
Stella de Haan, Marine Dourte, Michele Deantoni, Mathilde Reyt, Marion Baillet, Christian Berthomier, Vincenzo Muto, Gregory Hammad, Christian Cajochen, Carolin F. Reichert, Micheline Maire, Christina Schmidt, Svetlana Postnova   +12 more
doaj   +1 more source

A Conserved Circadian Function for the Neurofibromatosis 1 Gene

Cell Reports, 2018
Summary: Loss of the Neurofibromatosis 1 (Nf1) protein, neurofibromin, in Drosophila disrupts circadian rhythms of locomotor activity without impairing central clock function, suggesting effects downstream of the clock.
Lei Bai, Yool Lee, Cynthia T. Hsu, Julie A. Williams, Daniel Cavanaugh, Xiangzhong Zheng, Carly Stein, Paula Haynes, Han Wang, David H. Gutmann, Amita Sehgal   +10 more
doaj   +1 more source