Results 41 to 50 of about 11,095 (223)

A medullary hub for controlling REM sleep and pontine waves

open access: yesNature Communications, 2023
Rapid-eye-movement (REM) sleep is a distinct behavioral state associated with vivid dreaming and memory processing. Phasic bursts of electrical activity, measurable as spike-like pontine (P)-waves, are a hallmark of REM sleep implicated in memory ...
Amanda L. Schott   +3 more
doaj   +1 more source

Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness

open access: yesScientific Reports, 2017
We tested the effect of different lights as a countermeasure against sleep-loss decrements in alertness, melatonin and cortisol profile, skin temperature and wrist motor activity in healthy young and older volunteers under extendend wakefulness. 26 young
Virginie Gabel   +8 more
doaj   +1 more source

A circadian clock regulates efflux by the blood-brain barrier in mice and human cells

open access: yesNature Communications, 2021
The blood-brain barrier is critical for neural function. Here, the authors show that efflux of xenobiotics through the BBB follows a circadian rhythm in mice and human cells.
Shirley L. Zhang   +6 more
doaj   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

open access: yesAdvanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari   +3 more
wiley   +1 more source

Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent

open access: yesScientific Reports, 2017
The central circadian pacemaker (Suprachiasmatic Nuclei, SCN) maintains the phase relationship with the external world thanks to the light/dark cycle. Light intensity, spectra, and timing are important for SCN synchronisation.
Maria Angeles Bonmati-Carrion   +3 more
doaj   +1 more source

Weight loss in conservative treatment of obesity in women is associated with physical activity and circadian phenotype: a longitudinal observational study

open access: yesBioPsychoSocial Medicine, 2019
Introduction The study investigates the association between circadian phenotype (CP), its stability (interdaily stability - IS) and physical activity (PA) in a weight loss (WL) programme.
Eva Fárková   +8 more
doaj   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel   +13 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

open access: yesFood Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima   +4 more
wiley   +1 more source

History and perspectives of Chronobiology in Brazil and Latin America

open access: yes, 2023
This book is intended as a record of the history of implantation of Chronobiology in Brazil and Latin America. Is is written in Portuguese with contributions of colleagues from Latin America (texts in spanish).
Menna-Barreto, Luiz, Marques, Nelson
core   +1 more source

The Role of HUWE1 on Mouse Neural Cell Proliferation and Zebrafish Neurodevelopment

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT The HECT, UBA, and WWE domain‐containing E3 ubiquitin protein ligase 1 (HUWE1) gene is located on the X chromosome and has been implicated in neurodevelopmental disorders. However, the mechanisms by which HUWE1 dosage affects nervous system development remain poorly understood. In this study, we demonstrate that HUWE1 overexpression suppresses
Haojuan Wu   +10 more
wiley   +1 more source

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