Results 71 to 80 of about 24,205 (255)

Ecological, Functional, and Phylogenetic Determinants of Cyanobacterial Biomineralisation

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Cyanobacteria contribute to the global carbon cycle by biomineralising CO2 into solid carbonates. Unlike photosynthesis, biomineralisation is a less‐understood, multifaceted and adaptive metabolic process with significant global impact. It involves cell wall structures, genetic factors, and metabolic pathways that enable mineral formation and help ...
Federica Tiddia, Sandeesha Kodru, Dario Piano, Domenica Farci   +3 more
wiley   +1 more source

Impact of peripheral circadian misalignment and alcohol on the resiliency of intestinal barrier and microbiota

Gut Microbes
Circadian organization is involved in many gastrointestinal tract (GIT) functions such as the maintenance of intestinal barrier integrity. There is compelling evidence that perturbation of the circadian clock decreases intestinal epithelial cells ...
Laura Tran, Maliha Shaikh, Phillip A. Engen, Ankur Naqib, Dulce M. Frausto, Vivian Ramirez, Malia Gasteier, Zlata Bogin, Kristi Lawrence, Lijuan Zhang, Shiwen Song, Stefan J. Green, Faraz Bishehsari, Christopher B. Forsyth, Ali Keshavarzian, Garth R. Swanson   +15 more
doaj   +1 more source

Endothelial MLKL Inhibition Reduces Hyperoxia‐Induced Bronchopulmonary Dysplasia in Neonatal Mice

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Bronchopulmonary dysplasia (BPD) remains a severe complication in premature infants requiring prolonged oxygen therapy, with vascular endothelial dysfunction recognised as a critical contributor to disease progression. Mixed lineage kinase domain‐like protein (MLKL)‐mediated necroptosis, an essential form of regulated cell death implicated in ...
Junjie Ning, Junchao Deng, Yating Sang, Lina Qiao   +3 more
wiley   +1 more source

Afternoon to early evening bright light exposure reduces later melatonin production in adolescents

npj Biological Timing and Sleep
Whether light exposure during the day reduces non-visual light effects later in the evening has not been studied in adolescents. We investigate whether afternoon-early evening (AEE) light interventions (130 lx, 2500 lx, 4.5 h, compared to 6.5 lx ...
Rafael Lazar, Fatemeh Fazlali, Marine Dourte, Christian Epple, Oliver Stefani, Manuel Spitschan, Christian Cajochen   +6 more
doaj   +1 more source

Impact of Varying Sleep Pressure on Daytime Sleep Propensity in Healthy Young and Older Adults

Clocks & Sleep
Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals.
Stella de Haan, Marine Dourte, Michele Deantoni, Mathilde Reyt, Marion Baillet, Christian Berthomier, Vincenzo Muto, Gregory Hammad, Christian Cajochen, Carolin F. Reichert, Micheline Maire, Christina Schmidt, Svetlana Postnova   +12 more
doaj   +1 more source

Coupling governs entrainment range of circadian clocks

Molecular Systems Biology, 2010
Circadian clocks are endogenous oscillators driving daily rhythms in physiology and behavior. Synchronization of these timers to environmental light–dark cycles (‘entrainment’) is crucial for an organism's fitness.
Ute Abraham, Adrián E Granada, Pål O Westermark, Markus Heine, Achim Kramer, Hanspeter Herzel   +5 more
doaj   +1 more source

Chrono-biology, Chrono-pharmacology, and Chrono-nutrition

Journal of Pharmacological Sciences, 2014
The circadian clock system in mammals drives many physiological processes including the daily rhythms of sleep–wake behavior, hormonal secretion, and metabolism.
Yu Tahara, Shigenobu Shibata
doaj   +1 more source

Production and characterization of CSSI003 (2961) human induced pluripotent stem cells (iPSCs) carrying a novel puntiform mutation in RAI1 gene, Causative of Smith–Magenis syndrome [PDF]

, 2018
Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by developmental delay, behavioural problems and circadian rhythm dysregulation. About 90% of SMS cases are due to a 17p11.2 deletion containing retinoic acid induced1 (RAI1) gene,
Altieri, Filomena, Bernardini, Laura, DE JACO, Antonella, Della Monica, Matteo, Ferrari, Daniela, Lamorte, Giuseppe, Luigi Vescovi, Angelo, Mazzoccoli, Gianluigi, Nardone, Annamaria, Rosati, Jessica Diana, Torres, Barbara, Turco, ELISA MARIA, Vinci, Ersilia   +12 more
core   +3 more sources

Acute Effects of Oral Cannabinoids on Sleep and High‐Density EEG in Insomnia: A Pilot Randomised Controlled Trial

Journal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT Cannabinoids, particularly Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have gained popularity as alternative sleep aids; however, their effects on sleep architecture and next‐day function remain poorly understood. Here, in a pilot trial, we examined the effects of a single oral dose containing 10 mg THC and 200 mg CBD (THC/CBD) on ...
Anastasia Suraev, Iain S. McGregor, Danielle McCartney, Nathaniel S. Marshall, Chien‐Hui Kao, Rick Wassing, Angela L. D'Rozario, Keith K. H. Wong, Brendon J. Yee, Sheila Sivam, Richard C. Kevin, Ryan Vandrey, Christopher Irwin, Christopher J. Gordon, Delwyn Bartlett, Jonathon C. Arnold, Ronald R. Grunstein, Camilla M. Hoyos   +17 more
wiley   +1 more source

Editorial: Roles of the Circadian Rhythms in Metabolic Disease and Health

Metabolites
Chronobiology is the field of study focused on understanding the temporal patterns of biological functions, specifically examining the regular cycles or oscillations in these processes [...]
Letizia Galasso, Lucia Castelli, Eleonora Bruno   +2 more
doaj   +1 more source