Results 71 to 80 of about 23,161 (222)

Exploring the uncertain relationship between lunar phases and human sleep duration and quality: A narrative literature review​ [PDF]

, 2020
The moon’s influence on human behavior has been the subject of speculation for a large portion of history. A whole host of physiological and psychological disorders were collectively explained away by lunacy or madness until the advent of modern science ...
Skrobul, Nicholas
core   +1 more source

Production and characterization of CSSI003 (2961) human induced pluripotent stem cells (iPSCs) carrying a novel puntiform mutation in RAI1 gene, Causative of Smith–Magenis syndrome [PDF]

, 2018
Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by developmental delay, behavioural problems and circadian rhythm dysregulation. About 90% of SMS cases are due to a 17p11.2 deletion containing retinoic acid induced1 (RAI1) gene,
Altieri, Filomena, Bernardini, Laura, DE JACO, Antonella, Della Monica, Matteo, Ferrari, Daniela, Lamorte, Giuseppe, Luigi Vescovi, Angelo, Mazzoccoli, Gianluigi, Nardone, Annamaria, Rosati, Jessica Diana, Torres, Barbara, Turco, ELISA MARIA, Vinci, Ersilia   +12 more
core   +3 more sources

Imaging Multidimensional Therapeutically Relevant Circadian Relationships

International Journal of Biomedical Imaging, 2009
Circadian clocks gate cellular proliferation and, thereby, therapeutically target availability within proliferative pathways. This temporal coordination occurs within both cancerous and noncancerous proliferating tissues.
Jamil Singletary, Patricia A. Wood, Jovelyn Du-Quiton, Song Wang, Xiaoming Yang, Shobhit Vishnoi, William J. M. Hrushesky   +6 more
doaj   +1 more source

Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3295-3304, April 2026.
Abstract Aims Little is known about how the alignment between daily behaviours, such as physical activity and eating, and chronotype relates to glucose metabolism. We investigated whether alignment of physical activity and meal timing with chronotype was associated with glycaemic parameters and with prediabetes or type 2 diabetes (T2DM).
Marvin Y. Chong, Joseph Henson, Martijn J. L. Bours, Hans Bosma, Bastiaan E. de Galan, Carla J. H. van der Kallen, Ree M. Meertens, Hans H. C. M. Savelberg, Miranda T. Schram, Matty P. Weijenberg, Thomas Yates, Annemarie Koster, Simone J. P. M. Eussen   +12 more
wiley   +1 more source

A Conserved Circadian Function for the Neurofibromatosis 1 Gene

Cell Reports, 2018
Summary: Loss of the Neurofibromatosis 1 (Nf1) protein, neurofibromin, in Drosophila disrupts circadian rhythms of locomotor activity without impairing central clock function, suggesting effects downstream of the clock.
Lei Bai, Yool Lee, Cynthia T. Hsu, Julie A. Williams, Daniel Cavanaugh, Xiangzhong Zheng, Carly Stein, Paula Haynes, Han Wang, David H. Gutmann, Amita Sehgal   +10 more
doaj   +1 more source

Afternoon to early evening bright light exposure reduces later melatonin production in adolescents

npj Biological Timing and Sleep
Whether light exposure during the day reduces non-visual light effects later in the evening has not been studied in adolescents. We investigate whether afternoon-early evening (AEE) light interventions (130 lx, 2500 lx, 4.5 h, compared to 6.5 lx ...
Rafael Lazar, Fatemeh Fazlali, Marine Dourte, Christian Epple, Oliver Stefani, Manuel Spitschan, Christian Cajochen   +6 more
doaj   +1 more source

Impact of peripheral circadian misalignment and alcohol on the resiliency of intestinal barrier and microbiota

Gut Microbes
Circadian organization is involved in many gastrointestinal tract (GIT) functions such as the maintenance of intestinal barrier integrity. There is compelling evidence that perturbation of the circadian clock decreases intestinal epithelial cells ...
Laura Tran, Maliha Shaikh, Phillip A. Engen, Ankur Naqib, Dulce M. Frausto, Vivian Ramirez, Malia Gasteier, Zlata Bogin, Kristi Lawrence, Lijuan Zhang, Shiwen Song, Stefan J. Green, Faraz Bishehsari, Christopher B. Forsyth, Ali Keshavarzian, Garth R. Swanson   +15 more
doaj   +1 more source

Chronobiology and Mood Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2011
Living organizms show cyclic rhythmicity in a variety of physiological, hormonal, behavioral, and psychological processes. Sleep-wake cycles, body temperature, hormone levels, mood and cognition display a circadian rhythm in humans.
Yavuz Selvi, Lutfullah Besiroglu, Adem Aydin   +2 more
doaj  

Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]

, 2019
Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C., Bottazzi, B., DelGiudice, G., Denoel, P., Greenwood, A., Jonsdottir, I., Kaufmann, S., Kester, K., Leroux-Roels, G., Lewis, D., Linley, C., Maertzdorf, J., Mantovani, A., Mollenkopf, H., Pizzoferro, K., van den Berg, R., Weiner, J.   +16 more
core   +1 more source

Impact of Varying Sleep Pressure on Daytime Sleep Propensity in Healthy Young and Older Adults

Clocks & Sleep
Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals.
Stella de Haan, Marine Dourte, Michele Deantoni, Mathilde Reyt, Marion Baillet, Christian Berthomier, Vincenzo Muto, Gregory Hammad, Christian Cajochen, Carolin F. Reichert, Micheline Maire, Christina Schmidt, Svetlana Postnova   +12 more
doaj   +1 more source