Results 91 to 100 of about 11,633 (231)

Furin‐Mediated Cleavage of Zona Pellucida Proteins Is Essential for Oocyte Development

open access: yesMedComm, Volume 6, Issue 12, December 2025.
The furin cleavage site mutation leads to a failure in transmembrane transport process of non‐modified ZP2 protein. This unsuccessful ZP2 secretion might result in the decreased expression of exocytosis complex SNAREs, which further induces oocyte apoptosis via p53 pathway and PI3K signaling.
Tiechao Ruan   +15 more
wiley   +1 more source

Effects of light, electromagnetic fields and water on biological rhythms

open access: yesBiomedical Journal
The circadian rhythm controls a wide range of functions in the human body and is required for optimal health. Disruption of the circadian rhythm can produce inflammation and initiate or aggravate chronic diseases.
Jan Martel   +5 more
doaj   +1 more source

The Effect of the Season of Birth on Empathic Accuracy and Motor Mimicry [PDF]

open access: yes, 2018
Several studies have reported significant relationships between the season of birth and personality. An experiment was conducted to test the hypothesis if winter births have high scores on sensation seeking, or a tendency for morningness chronotype, then
Kushizaki Masashi, 串崎 真志
core   +1 more source

Cortical–subcortical interactions in hypersomnia disorders: Mechanisms underlying cognitive and behavioral aspects of the sleep–wake cycle [PDF]

open access: yes, 2014
Subcortical circuits mediating sleep–wake functions have been well characterized in animal models, and corroborated by more recent human studies. Disruptions in these circuits have been identified in hypersomnia disorders (HDs) such as narcolepsy and ...
Galvin, James E   +2 more
core   +2 more sources

Ikelos‐Rating Scale: Validation of a Behavioural Severity Marker in REM Sleep Behaviour Disorder

open access: yesJournal of Sleep Research, Volume 34, Issue 6, December 2025.
ABSTRACT The Ikelos‐Rating Scale (Ikelos‐RS) is a new, expert‐interviewed and bedpartner‐reported severity marker assessing frequency and expression of isolated REM sleep behaviour disorder (iRBD), a precursor of clinical α‐synucleinopathies. This study aimed to validate the Ikelos‐RS in 180 patients with three‐night PSG‐confirmed iRBD (68.4 ± 8.3 ...
Sophia Stotz, Frederik Bes, Dieter Kunz
wiley   +1 more source

Pedunculopontine nucleus gamma band activity-preconscious awareness, waking, and REM sleep [PDF]

open access: yes, 2014
The pedunculopontine nucleus (PPN) is a major component of the reticular activating system (RAS) that regulates waking and REM sleep, states of high-frequency EEG activity.
Beck, Paige B.   +6 more
core   +2 more sources

Chronobiological Aspects of Mood Disorders

open access: yes, 2012
Mood disorders, especially those related to depression, are among the most prevalent mental impairments. Therefore, understanding their etiology is important for prevention and improving therapy. Sub-clinical depressive symptoms, which predict the onset of mood and anxiety disorders (Gentil et al., 2007), are correlated with slow information processing,
Levandovski, Rosa   +3 more
openaire   +3 more sources

Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression

open access: yesEuropean Psychiatry
Background Increasing daylight exposure might be a simple way to improve mental health. However, little is known about daylight-symptom associations in depressive disorders. Methods In a subset of the Australian Genetics of Depression Study (N = 13,480;
Jacob J. Crouse   +12 more
doaj   +1 more source

Improved insulin sensitivity following a short-term whole body vibration intervention [PDF]

open access: yes, 2017
Background and Objective: Despite being recommended for reducing the risk of type 2 diabetes (T2D) the majority of the population do not partake in the advised amount of regular exercise.
Babraj, John, Hawkey, Adam
core   +2 more sources

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