Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology. [PDF]
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Baud MO +4 more
europepmc +2 more sources
Time after time - circadian clocks through the lens of oscillator theory. [PDF]
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Del Olmo M, Ector C, Herzel H.
europepmc +2 more sources
Could photoperiodic responses have evolved before the emergence of circadian clocks? [PDF]
Summary Plants use photoperiod (i.e. day length) as a seasonal cue for timing when to flower. This ability, known as photoperiodism, also underlies phenomena such as migration, seasonal reproduction, and hibernation in animals. Because a circadian (daily) clock underlies the day/night length timing mechanism in most organisms, it has been generally ...
Jabbur ML, Johnson CH.
europepmc +2 more sources
Digital Sleep Disruption: Unraveling the Network Structure of Technology Use and Sleep Problems Through Network Analysis. [PDF]
In 9443 Chinese adults, network analysis reveals blue light exposure as the central factor most strongly associated with sleep problems (r = 0.31). General screen time shows minimal direct effects (r = 0.03), with sleep disruption mediated through evening‐specific behaviors.
Gan H, Xu L, Tong C.
europepmc +2 more sources
Twenty-Four Hour Rhythms in Cardiovascular Physiology. [PDF]
ABSTRACT Many physiological parameters, such as heart rate and blood pressure, display pronounced daily rhythms, with significant differences between day and night levels. The ability to anticipate the 24 h cycle of ambient light confers an adaptive advantage, allowing organisms to prepare for periods of activity and rest.
Thomsen MB.
europepmc +2 more sources
Inclusion, reporting and analysis of demographic variables in chronobiology and sleep research [PDF]
Tir S, White R, Spitschan M.
exaly +2 more sources
Atlas-Based Mapping of Traditional Chinese Medicine Effects on Tumor Microcirculation Regulation. [PDF]
ABSTRACT Background Tumor microcirculation plays a central role in the onset and progression of hypoxia, therapeutic resistance, and immune evasion within the tumor microenvironment. Traditional Chinese Medicine (TCM), characterized by its multi‐targeted and systemic regulatory properties, has garnered increasing attention for its potential to modulate
Ho I, Xie Y, Liu Z, Cai D.
europepmc +2 more sources
Background Young adults are likely to have activities and go to bed late at night due to their age-dependent delayed endogenous circadian clock. The purpose of the present study was to clarify sleep–wake rhythm and its association with lifestyle, health ...
Momoko Kayaba +4 more
doaj +1 more source
The circadian clock controls behavior and physiology. Presently, there is clear evidence of a connection between this timing system and cancer development/progression. Moreover, circadian rhythm consideration in the therapeutic action of anticancer drugs
Tânia Albuquerque +8 more
doaj +1 more source
A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics [PDF]
Cellular, organ, and whole animal physiology show temporal variation predominantly featuring 24-h (circadian) periodicity. Time-course mRNA gene expression profiling in mouse liver showed two subsets of genes oscillating at the second (12-h) and third (8-
Biagini, Tommaso +11 more
core +1 more source

