Results 121 to 130 of about 83,142 (245)

Receptive–Expressive Language Phenotypes in Infants and Toddlers With Autism Features

Autism Research, EarlyView.
ABSTRACT Children diagnosed with autism often present with an atypical discrepancy between their receptive and expressive language levels, or an atypical receptive–expressive language phenotype. Children with an atypical receptive–expressive phenotype present with a relative receptive language advantage (expressive level < receptive level) or a ...
Torrey Cohenour, Amanda Gulsrud, Connie Kasari   +2 more
wiley   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

PCSK9 inhibitors and aging: Does chronological age matter? [PDF]

Atherosclerosis
Mouslmani MA, Nouri A, Damluji AA, Nanna MG.   +3 more
europepmc   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Laparoscopic Resection for Rectal Cancer in a Centenarian: A Case Report Highlighting the Importance of Functional Independence over Chronological Age. [PDF]

Surg Case Rep
Tokinaga A, Teraishi F, Onoda N, Omoto K, Takahashi R, Okabayashi H, Utsumi M, Miyaso H, Otsuka S, Inagaki M.   +9 more
europepmc   +1 more source

The differential effect of chronological age and brain age on cognitive fatigue: new metrics, new insights. [PDF]

J Neurol
Wylie GR, Román CAF, Buckey JC, Chiaravalloti ND, Falvo MJ, Ford JC, Genova HM, Niemczak CE, Roth RM, DeLuca J.   +9 more
europepmc   +1 more source

The quality of interaction with children in collective play: Children's agency

British Educational Research Journal, EarlyView.
Abstract There is a growing body of studies on increasing the quality of infant–toddler education and care. Yet little attention has been directed towards how to bring toddlers' agency and perspective to their personally meaningful learning in collective play.
Liang Li
wiley   +1 more source

Frailty-Informed Pain Management: A Clinical Imperative Beyond Chronological Age. [PDF]

Drugs Aging
Mourelle-Sanmartín P, Lorenzo-López L, Millán-Calenti JC, Andrew MK, Theou O.   +4 more
europepmc   +1 more source

‘Where are the adults?’: Troubling child‐activism and children's political participation

British Educational Research Journal, EarlyView.
Abstract Children's political participation is a well‐established theme in childhood studies. In this article we offer an original account of child activism that takes into account the entangled and emergent aspect of children as activists. We begin with a historical and a conceptual review, noting the importance of mid‐20th century developments such ...
Sharon Hunter, Claire Cassidy
wiley   +1 more source