Results 31 to 40 of about 28,534 (260)
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Intrinsic water-use efficiency (W i ) reconstructions using tree rings often disregard developmental changes in W i as trees age. Here, the authors compare W i across varying tree sizes at a fixed CO2 level and show that ignoring developmental changes ...
R. J. W. Brienen +14 more
doaj +1 more source
Current State of Knowledge of the Development of Early Modern Ceramics in the Czech Republic
This study is an overview of the professional interest in archaeology of the modern age in the Czech Republic. Increased interest in the archaeology of the Modern period came after the year 2000.
Gabriela Blažková
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The present paper was based on 351 settlements identified in the archaeological literature throughout the highland and lowland areas of the Banat, dated between the 2nd century and the beginning of the 5th century AD.
Lavinia Grumeza
doaj +1 more source
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
The Maillot “Les Terres du Terrier” site (Yonne) was excavated in 1947 by J. Coudray and P. Parruzot. One structure produced more than 20kg of potsherds.
Fabrice Muller +2 more
doaj +1 more source
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Satellite data indicates recent Arctic peatland expansion with warming
Northern peatlands are an important carbon store in mid to high latitudes, but become increasingly discontinuous in the higher latitudes, associated with temperature and precipitation limits on plant growth.
K. A. Crichton +12 more
doaj +1 more source

