Results 41 to 50 of about 176,515 (348)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

The chronology of the Aegean late bronze age with special reference to the "Minoan” eruption of Thera [PDF]

open access: yes, 2002
The chronology of the Aegean Late Bronze Age is a vigorously contested area of archaeological study, with "high" and "low" schemes emerging over the last three decades.
Dunn, Stuart E
core  

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Tree height strongly affects estimates of water-use efficiency responses to climate and CO2 using isotopes

open access: yesNature Communications, 2017
Intrinsic water-use efficiency (W i ) reconstructions using tree rings often disregard developmental changes in W i as trees age. Here, the authors compare W i across varying tree sizes at a fixed CO2 level and show that ignoring developmental changes ...
R. J. W. Brienen   +14 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

SETTLEMENTS FROM THE 2ND-EARLY 5TH CENTURY AD IN BANAT (I). STATE OF RESEARCH AND THE INTERPRETATION OF THE DISCOVERIES FROM ROMANIA

open access: yesJournal of Ancient History and Archaeology, 2015
The present paper was based on 351 settlements identified in the archaeological literature throughout the highland and lowland areas of the Banat, dated between the 2nd century and the beginning of the 5th century AD.
Lavinia Grumeza
doaj   +1 more source

Current State of Knowledge of the Development of Early Modern Ceramics in the Czech Republic

open access: yesArchaeologia Polona, 2021
This study is an overview of the professional interest in archaeology of the modern age in the Czech Republic. Increased interest in the archaeology of the Modern period came after the year 2000.
Gabriela Blažková
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

Maillot « Les Terres du Terrier » (Yonne) : typo-chronologie d’un ensemble céramique du début du Bronze final

open access: yesRevue Archéologique de l’Est, 2008
The Maillot “Les Terres du Terrier” site (Yonne) was excavated in 1947 by J. Coudray and P. Parruzot. One structure produced more than 20kg of potsherds.
Fabrice Muller   +2 more
doaj   +1 more source

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

open access: yesAdvanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

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