Results 41 to 50 of about 176,515 (348)
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
The chronology of the Aegean late bronze age with special reference to the "Minoan” eruption of Thera [PDF]
The chronology of the Aegean Late Bronze Age is a vigorously contested area of archaeological study, with "high" and "low" schemes emerging over the last three decades.
Dunn, Stuart E
core
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Intrinsic water-use efficiency (W i ) reconstructions using tree rings often disregard developmental changes in W i as trees age. Here, the authors compare W i across varying tree sizes at a fixed CO2 level and show that ignoring developmental changes ...
R. J. W. Brienen +14 more
doaj +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
The present paper was based on 351 settlements identified in the archaeological literature throughout the highland and lowland areas of the Banat, dated between the 2nd century and the beginning of the 5th century AD.
Lavinia Grumeza
doaj +1 more source
Current State of Knowledge of the Development of Early Modern Ceramics in the Czech Republic
This study is an overview of the professional interest in archaeology of the modern age in the Czech Republic. Increased interest in the archaeology of the Modern period came after the year 2000.
Gabriela Blažková
doaj +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
The Maillot “Les Terres du Terrier” site (Yonne) was excavated in 1947 by J. Coudray and P. Parruzot. One structure produced more than 20kg of potsherds.
Fabrice Muller +2 more
doaj +1 more source
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley +1 more source

