Results 1 to 10 of about 3,261 (163)

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

Genome Biology, 2021
CRISPR loss of function screens are powerful tools to interrogate biology but exhibit a number of biases and artifacts that can confound the results.
Joshua M Dempster, Isabella Boyle, Francisca Vazquez   +2 more
exaly   +2 more sources

A comparative evaluation of time-series models for forecasting inpatient deaths and discharges against medical advice [PDF]

Scientific Reports
Forecasting inpatient mortality (IM) and discharges against medical advice (DAMA) provides essential insights for healthcare quality monitoring and hospital management.
Cheng Pang, Dexi Jiayong, Dandan Jiang, Yi Wang, Naishi Li, Dan Ren   +5 more
doaj   +2 more sources

Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats

BMC Microbiology, 2022
Background Obesity, metabolic disease and some psychiatric conditions are associated with changes to relative abundance of bacterial species and specific genes in the faecal microbiome. Little is known about the impact of pharmacologically induced weight
Silvia Raineri, Julia A. Sherriff, Kevin S. J. Thompson, Huw Jones, Paul T. Pfluger, Nicholas E. Ilott, Jane Mellor   +6 more
doaj   +1 more source

Plate osteosynthesis combined with bone cement provides the highest stability for tibial head depression fractures under high loading conditions

Scientific Reports, 2022
Older patients sustaining tibial head depression fractures often cannot follow the post-operative rehabilitation protocols with partial weight-bearing of the affected limb, leading to osteosynthesis failure, cartilage step-off and arthritis development ...
Philipp Heilig, Lars-Christopher Faerber, Mila M. Paul, Eva Kupczyk, Rainer H. Meffert, Martin C. Jordan, Stefanie Hoelscher-Doht   +6 more
doaj   +1 more source

Korporativ denken, genossenschaftlich organisieren, feudal handeln: Die Gemeinden und ihre Praktiken im Bergell des 14.–16. Jahrhunderts [Thinking Corporately, Organizing Cooperatively, Acting Feudally: Communes and Their Practices in Val Bregaglia in the 14th–16th Centuries]. By Prisca Roth

Mountain Research and Development, 2022
Reviewed: Korporativ denken, genossenschaftlich organisieren, feudal handeln: Die Gemeinden und ihre Praktiken im Bergell des 14.–16. Jahrhunderts. By Prisca Roth. Zurich, Switzerland: Chronos, 2018. 427 pp. Hardcover: € 58.00. ISBN 978-3-0340-1447-2.
Manfred Perlik
doaj   +1 more source

Feasibility of Comparative Health Research Outcome of Novel Surgery in prostate cancer (IP4-CHRONOS): statistical analysis plan for the randomised feasibility phase of the CHRONOS study

Trials, 2021
Background Randomised controlled trials (RCTs) for surgical interventions have often proven difficult with calls for innovative approaches. The Imperial Prostate (IP4) Comparative Health Research Outcomes of Novel Surgery in prostate cancer (IP4-CHRONOS)
Emily Day, A. Toby Prevost, Matthew R. Sydes, Deepika Reddy, Taimur T. Shah, Mathias Winkler, Tim Dudderidge, John Staffurth, Stuart McCracken, Vincent Khoo, Puja Jadav, Natalia Klimowska-Nassar, Thiagarajah Sasikaran, Hashim U. Ahmed, Francesca Fiorentino   +14 more
doaj   +1 more source

The CHRONOS mission: capability for sub-hourly synoptic observations of carbon monoxide and methane to quantify emissions and transport of air pollution [PDF]

Atmospheric Measurement Techniques, 2018
The CHRONOS space mission concept provides time-resolved abundance for emissions and transport studies of the highly variable and highly uncertain air pollutants carbon monoxide and methane, with sub-hourly revisit rate at fine (∼ 4 km) horizontal ...
D. P. Edwards, H. M. Worden, D. Neil, G. Francis, T. Valle, A. F. Arellano Jr.   +5 more
doaj   +1 more source

The orthodox liturgical year and its theological structure

HTS Teologiese Studies/Theological Studies, 2021
The concept of ‘liturgical year’ indicates a reference to the meaning of the measuring units of civil time, and especially to the cosmic entities that determine the general rhythm of time – the sun and the moon. Interestingly, the liturgical time depends
Dan A. Streza
doaj   +1 more source

The CHRONOS Real-World Evidence of Biologic Treatments in Psoriatic Arthritis in Italy: A Post Hoc Gender Analysis

Women's Health Reports, 2022
Background: Phenotypic features and outcome differences between sexes have been reported in psoriatic arthritis (PsA). However, little is known about sex differences in effectiveness of biologics in clinical practice. Methods: Post hoc gender analysis of
Delia Colombo, Micol Frassi, Giuseppa Pagano Mariano, Enrico Fusaro, Claudia Lomater, Patrizia Del Medico, Florenzo Iannone, Rosario Foti, Massimiliano Limonta, Antonio Marchesoni, Bernd Raffeiner, Ombretta Viapiana, Marco Di Carlo, Rosa Daniela Grembiale, Giuliana Guggino, Paola Faggioli, Enrico Tirri, Roberto Perricone, Pier Carlo Sarzi Puttini, Salvatore De Vita, Fabrizio Conti, Sara Rizzoli, Barbara Roncari, Martina Fiocchi, Roberto Orsenigo, Emanuela Zagni, Collaboration group, Collaboration group, Frassi Micol, Caminiti Maurizio, Fusaro Enrico, Lomater Claudia, Del Medico Patrizia, Iannone Fiorenzo, Foti Rosario, Limonta Massimiliano, Marchesoni Antonio, Raffeiner Bernd, Viapiana Ombretta, Grassi Walter, Grembiale Rosa Daniela, Guggino Giuliana, Mazzone Antonino, Tirri Enrico, Perricone Roberto, Sarzi Puttini Pier Carlo, De Vita Salvatore, Conti Fabrizio   +47 more
doaj   +1 more source

aufgesplittert, ausgedehnt. Mark Bardens kairos incised (2007) [PDF]

Zeitschrift der Gesellschaft für Musiktheorie, 2010
Das Ensemblestück kairos incised ist Mark Bardens kompositorische Auseinandersetzung mit der Vorstellung eines entscheidenden, Veränderung herbeiführenden Augenblicks, der dem quantitativen Verstreichen der Zeit enthoben ist.
Andreas Lang
doaj   +1 more source