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Churg-Strauss-Syndrom

DMW - Deutsche Medizinische Wochenschrift, 2008
In a 47-year-old man presenting with chronic bronchitis since 1978, a weight loss of 11 kg in 9 months and deteriorated general condition, the x-ray film of the thorax revealed numerous pulmonary nodules of up to 4 cm size. Laboratory findings were characterised by enhanced ESR, blood eosinophilia of 7% and a lot of eosinophilic granulocytes in the ...
C S, Kortsik   +5 more
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Churg-Strauss-Syndrom

Klinische Monatsblätter für Augenheilkunde, 1999
The Churg-Strauss syndrome, also known as allergic granulomatosis with angiitis, is a rare necrotizing vasculitis with unknown pathogenesis. The necrotizing granulomatous vasculitis involves small and medium-sized arteries, capillaries and veins, leading to the characteristic changes of intra- and extravascular, eosiniphilic granulomas, accompanied by ...
N, Stübiger   +3 more
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Churg–Strauss syndrome

Current Opinion in Rheumatology, 2007
Churg-Strauss syndrome is a small-vessel necrotizing vasculitis typically characterized by asthma, lung infiltrates, extravascular necrotizing granulomas and hypereosinophilia. The most recent clinical studies on its pathogenesis and therapeutic management are reviewed here.French and Italian clinical studies found that the clinical characteristics of ...
Christian, Pagnoux   +2 more
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A case of Churg-Strauss syndrome

Zeitschrift f�r Rechtsmedizin, 1989
A 54-year-old woman died after being battered, but the forensic autopsy revealed that her injuries were not serious or lethal. A detailed histological examination revealed that the basic disease had been Churg-Strauss syndrome. The differentiation of this syndrome of pulmonary infiltration and eosinophilia (PIE syndrome) from other allergic and ...
M, Varga, L, Debreczeni
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Interleukins in Churg‐Strauss syndrome

Allergy, 2000
and eight times greater than those observed with the negative control. Cross-reactions between both antigens were not observed. Activity against collagen has been demonstrated (4) in the G. gigas plerocercoid stage and is presumably involved in its penetration processes.
M, Kurosawa   +11 more
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Steroids and Churg-Strauss syndrome

The Lancet, 1998
Leukotriene receptor antagonists have been introduced for the treatment of asthma. These drugs counteract the inflammation, bronchospasm, and airway oedema caused by leukotrienes. The first of these agents used as a commercial product, zafirlukast (Accolate, Zeneca Pharmaceuticals), has been reported to be effective, with few and mild adverse reactions.
A, Churg, J, Churg
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Update Churg-Strauss-Syndrom

Zeitschrift für Rheumatologie, 2012
The Churg-Strauss syndrome (CSS) is the rarest subtype of the so-called anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) and has the lowest frequency of ANCA-positivity (around 30%). In addition to asthma and blood eosinophilia, CSS is characterized by end-organ damage, which can be caused by either vasculitis and/or tissue ...
F, Moosig, B, Hellmich
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Churg Strauss syndrome in childhood

Annals of Tropical Paediatrics, 1995
We describe a 7-year-old boy with Churg Strauss syndrome who presented with a 3-month history of cough, wheeze, fever, weight loss, abdominal pain, skin lesions, proteinuria and pulmonary infiltrates with eosinophilia. He showed a good response to corticosteroid treatment and is currently doing well.
C, Mpofu   +3 more
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Renal Involvement in Churg-Strauss Syndrome

American Journal of Kidney Diseases, 2006
Churg-Strauss syndrome (CSS) is a rare disorder characterized by asthma, eosinophilia, and systemic vasculitis. Renal involvement is not regarded as a prominent feature, and its prevalence and severity vary widely in published reports that usually refer to small series of selected patients.We examined the prevalence, clinicopathologic features, and ...
SINICO, RENATO ALBERTO   +14 more
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Churg–Strauss syndrome

Current Opinion in Rheumatology, 2012
Churg-Strauss syndrome (CSS) has a clear clinical phenotype but its pathogenesis is not fully elucidated. Recent studies have focused on its immunogenetic aspects and cytokine and chemokine-mediated pathogenetic mechanisms, providing the rationale for the use of newer targeted therapies. This study will review recent findings on the pathogenesis of CSS
VAGLIO A, Moosig Frank, Zwerina Jochen
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