Results 1 to 10 of about 9,354,751 (270)

Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis [PDF]

New England Journal of Medicine, 2020
BACKGROUND More effective and safer treatments are needed for antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. METHODS We conducted a randomized trial with a 2-by-2 factorial design to evaluate the use of plasma exchange and two regimens
Oliver Floßmann, Christian Pagnoux, Loïc Guillevin   +2 more
exaly   +3 more sources

Avacopan for the Treatment of ANCA-Associated Vasculitis

New England Journal of Medicine, 2021
BACKGROUND The C5a receptor inhibitor avacopan is being studied for the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. METHODS In this randomized, controlled trial, we assigned patients with ANCA-associated vasculitis in
Peter A Merkel, David R Jayne, Pirow Bekker   +2 more
exaly   +7 more sources

Genetically Distinct Subsets Within ANCA-Associated Vasculitis

New England Journal of Medicine, 2012
BACKGROUND Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a severe condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly known as Wegener’s granulomatosis) and microscopic polyangiitis.
Mark A. Little, Loïc Guillevin, Thomas Neumann   +2 more
exaly   +3 more sources

Rituximab Versus Cyclophosphamide for ANCA-Associated Vasculitis

New England Journal of Medicine, 2010
BACKGROUND Cyclophosphamide and glucocorticoids have been the cornerstone of remission-induction therapy for severe antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis for 40 years.
Steven Ytterberg, John Stone, Linna Ding
exaly   +2 more sources

Kidney histopathology associated with kidney function at 1 year post severe AKI related to ANCA-associated vasculitis [PDF]

BMC Nephrology
Introduction ANCA-associated vasculitis is a rare autoimmune disease, and is particularly serious when the kidneys are involved. In addition to immunosuppressants, plasma exchanges are used to treat severe forms of vasculitis.
Léonard Cauchy, Pierre Raynaud, Pascal Reboul, Sylvain Cariou, Sophie Renaud, Émilie Pambrun, Pedram Ahmadpoor, Laurent Daniel, Hélène Perrochia, Camille Dubart, Sébastien Canet, Olivier Moranne, Florian Garo   +12 more
doaj   +2 more sources

Rituximab Versus Azathioprine for Maintenance in ANCA-Associated Vasculitis

New England Journal of Medicine, 2014
Christian Pagnoux, Loïc Guillevin, Bernard Bonnotte   +2 more
exaly   +2 more sources

EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update

Annals of the Rheumatic Diseases, 2023
Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials have been published that have the potential to change ...
B. Hellmich, B. Sánchez-Álamo, J. Schirmer, A. Berti, D. Blockmans, M. Cid, Julia U. Holle, Nicole Hollinger, O. Karadag, A. Kronbichler, M. Little, R. Luqmani, A. Mahr, P. Merkel, A. Mohammad, S. Monti, C. Mukhtyar, J. Musial, Fiona Price-Kuehne, M. Segelmark, Y. K. Onno Teng, B. Terrier, G. Tómasson, A. Vaglio, D. Vassilopoulos, P. Verhoeven, D. Jayne   +26 more
semanticscholar   +1 more source

Low levels of hemoglobin associate with critical illness and predict disease course in patients with ANCA-associated renal vasculitis

Scientific Reports, 2022
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel vasculitis often leading to critical illness by multi-organ failure.
Eva Baier, Desiree Tampe, Samy Hakroush, Björn Tampe   +3 more
doaj   +1 more source

Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma

Indian Journal of Rheumatology, 2021
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with ...
B N Shiva Prasad, H A Karthik Urala
doaj   +1 more source

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of ANCA-Associated Vasculitis

Arthritis care & research, 2021
To provide evidence‐based recommendations and expert guidance for the management of antineutrophil cytoplasmic antibody–associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic ...
Sharon A. Chung, C. Langford, M. Maz, A. Abril, M. Gorelik, G. Guyatt, A. Archer, D. Conn, Kathy A Full, P. Grayson, M. Ibarra, L. Imundo, Susan Kim, P. Merkel, Rennie L. Rhee, P. Seo, J. Stone, Sangeeta D. Sule, R. Sundel, Omar I Vitobaldi, A. Warner, K. Byram, A. Dua, Nedaa M. Husainat, K. James, Mohamad A. Kalot, Yih C. Lin, J. Springer, M. Turgunbaev, A. Villa-Forte, Amy S. Turner, R. Mustafa   +31 more
semanticscholar   +1 more source