Results 41 to 50 of about 17,989 (193)

The Pathogenicity of BPI-ANCA in a Patient With Systemic Vasculitis

Frontiers in Immunology, 2019
Objective: ANCA associated vasculitis (AAV) is characterized by systemic necrotizing vasculitis with the presence of ANCA. Although BPI-ANCA is one of the atypical ANCAs and is occasionally seen in patients with vasculitis, the pathogenicity of BPI-ANCA ...
Sayo Takeda, Kanako Watanabe-Kusunoki, Daigo Nakazawa, Yoshihiro Kusunoki, Saori Nishio, Tatsuya Atsumi   +5 more
doaj   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis in chronic Hepatitis B: Unraveling the immune puzzle - a rare case report with review of literature

IDCases
Background: Hepatitis B virus (HBV) infection affects millions worldwide, predominantly targeting the liver, leading to conditions like cirrhosis and hepatocellular cancer.
Suresh Bhagoowani, Uooja Devi, Aqsa Munir, Ummulkiram Hasnain, Javed Iqbal   +4 more
doaj   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

JEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato, Paolo Gisondi, Giampiero Girolomoni   +2 more
wiley   +1 more source

A Case of Methimazole Induced Leukocytoclastic Vasculitis

Endocrinology Research and Practice, 2005
Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis has been described frequently in patients treated with propylthiouracil (PTU). However, other antithyroid drugs, carbimazole and methimazole (MMI), rarely cause vasculitis.
Mustafa Kanat, Nadir Goksugur, Ali Haydar Parlak   +2 more
doaj   +2 more sources

A clinical case of ANCA-associated systemic vasculitis in a nine-yearold Sakha child

Якутский медицинский журнал
ANCA-associated vasculitis (AAV) is a group of diseases characterized by chronic immune inflammation of the wall of small vessels, a polymorphic clinical picture with frequent involvement of the lungs and kidneys, and the presence of circulating ...
O. N. Ivanova, V. M. Argunova, P. A. Sleptsova, M. V. Afonskaya, S. I. Innokentyeva, I. S. Ivanova, T. A. Argunova, T. E. Burtseva, O. L. Kolobova, I. A. Chikova, A. V. Santimov, M. M. Kostik   +11 more
doaj   +1 more source

ANCA associated vasculitis: experience of a tertiary care referral center

Brazilian Journal of Nephrology, 2018
Background and objectives: Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis is a small vessel vasculitis with insufficient epidemiologic estimates in the United States.
Rafia Chaudhry, Anum Bilal, Adam Austin, Swati Mehta, Loay Salman, Llewellyn Foulke, Paul Feustel, Roman Zuckerman, Arif Asif   +8 more
doaj   +1 more source

Hydralazine-induced pauci-immune glomerulonephritis: intriguing case series with misleading diagnoses [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
Hydralazine has been used since the 1950s for the management of hypertension. Evidence for hydralazine-associated vasculitis dates to pre-ANCA (antineutrophil cytoplasmic antibodies) era.
Faizan Babar, Jeffery N. Posner, Eugene A. Obah   +2 more
doaj   +1 more source

Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit

The Laryngoscope, EarlyView.
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann, David Oestreicher, Marc Albert Hüser, Dirk Beutner, Christian Wrobel   +4 more
wiley   +1 more source