Results 51 to 60 of about 8,073,410 (232)

The Pathogenicity of BPI-ANCA in a Patient With Systemic Vasculitis

Frontiers in Immunology, 2019
Objective: ANCA associated vasculitis (AAV) is characterized by systemic necrotizing vasculitis with the presence of ANCA. Although BPI-ANCA is one of the atypical ANCAs and is occasionally seen in patients with vasculitis, the pathogenicity of BPI-ANCA ...
Sayo Takeda, Kanako Watanabe-Kusunoki, Daigo Nakazawa, Yoshihiro Kusunoki, Saori Nishio, Tatsuya Atsumi   +5 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Avacopan for the Treatment of ANCA-Associated Vasculitis.

The New England journal of medicine, 2021
BACKGROUND: The C5a receptor inhibitor avacopan is being studied for the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. METHODS: In this randomized, controlled trial, we assigned patients with ANCA-associated vasculitis in a 1:1 ratio to receive oral avacopan at a dose of 30 mg twice daily or oral prednisone on a ...
Jayne D. R. W., Merkel P. A., Schall T. J., Bekker P., C Au Peh, A Chakera, B Cooper, J Kurtkoti, D Langguth, V Levidiotis, G Luxton, P Mount, D Mudge, E Noble, R Phoon, D Ranganathan, A Ritchie, J Ryan, M Suranyi, A Rosenkranz, K Lhotta, A Kronbichler, N Demoulin, C Bovy, R Hellemans, J Hougardy, B Sprangers, K Wissing, C Pagnoux, S Barbour, S Brachemi, S Cournoyer, L Girard, L Laurin, P Liang, D Philibert, M Walsh, V Tesar, R Becvar, P Horak, I Rychlik, W Szpirt, H Dieperink, J Gregersen, P Ivarsen, E Krarup, C Lyngsoe, C Rigothier, J Augusto, A Belot, D Chauveau, D Cornec, N Jourde-Chiche, M Ficheux, A Karras, A Klein, F Maurier, R Mesbah, O Moranne, A Neel, T Quemeneur, D Saadoun, B Terrier, P Zaoui, M Schaier, U Benck, R Bergner, M Busch, J Floege, F Grundmann, H Haller, M Haubitz, B Hellmich, J Henes, B Hohenstein, C Hugo, C Iking-Konert, F Arndt, T Kubacki, I Kotter, P Lamprecht, T Lindner, J Halbritter, H Mehling, U Schönermarck, N Venhoff, V Vielhauer, O Witzke, I Szombati, G Szucs, G Garibotto, F Alberici, E Brunetta, L Dagna, S De Vita, G Emmi, A Gabrielli, L Manenti, F Pieruzzi, D Roccatello, C Salvarani, H Dobashi, T Atsumi, S Fujimoto, N Hagino, A Ihata, S Kaname, Y Kaneko, A Katagiri, M Katayama, Y Kirino, K Kitagawa, A Komatsuda, H Kono, T Kurasawa, R Matsumura, T Mimura, A Morinobu, Y Murakawa, T Naniwa, T Nanki, N Ogawa, H Oshima, K Sada, E Sugiyama, T Takeuchi, H Taki, N Tamura, T Tsukamoto, K Yamagata, M Yamamura, P van Daele, A Rutgers, Y Teng, R Walker, I Chua, M Collins, K Rabindranath, J de Zoysa, M Svensson, B Grevbo, S Kalstad, M Little, M Clarkson, E Molloy, I Agraz Pamplona, J Anton, V Barrio Lucia, S Ciggaran, M Cinta Cid, M Diaz Encarnacion, X Fulladosa Oliveras, J M Soler, M H Rusinol, M Praga, L Quintana Porras, A Segarra, A Bruchfeld, M Segelmark, I Soveri, E Thomaidi, K Westman, T Neumann, M Burnier, T Daikeler, J Dudler, T Hauser, H Seeger, B Vogt, D Jayne, J Burton, R Al Jayyousi, T Amin, J Andrews, L Baines, P Brogan, B Dasgupta, T Doulton, O Flossmann, S Griffin, J Harper, L Harper, D Kidder, R Klocke, P Lanyon, R Luqmani, J McLaren, D Makanjuola, L McCann, A Nandagudi, S Selvan, E O'Riordan, M Patel, R Patel, C Pusey, R Rajakariar, J Robson, M Robson, A Salama, L Smyth   +199 more
openaire   +2 more sources

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis in chronic Hepatitis B: Unraveling the immune puzzle - a rare case report with review of literature

IDCases
Background: Hepatitis B virus (HBV) infection affects millions worldwide, predominantly targeting the liver, leading to conditions like cirrhosis and hepatocellular cancer.
Suresh Bhagoowani, Uooja Devi, Aqsa Munir, Ummulkiram Hasnain, Javed Iqbal   +4 more
doaj   +1 more source

Deep Learning‐Assisted Classification of Urinary Red Blood Cell Morphology for Glomerular Hematuria Screening: A Pilot Study

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective pilot study developed a YOLOv5l‐based deep learning system to detect and classify urinary red blood cells as isomorphic, dysmorphic, or unknown in urine sediment images. The model achieved a precision of 0.84, recall of 0.69, and F1‐score of 0.76 for dysmorphic RBCs, while sample‐level morphology scoring showed preliminary ...
Yih‐Lon Lin, Jung‐Sheng Chen, Ya‐Fan Chuang, Siang‐Ru Huang, Chien‐Sen Liao   +4 more
wiley   +1 more source

A Case of Methimazole Induced Leukocytoclastic Vasculitis

Endocrinology Research and Practice, 2005
Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis has been described frequently in patients treated with propylthiouracil (PTU). However, other antithyroid drugs, carbimazole and methimazole (MMI), rarely cause vasculitis.
Mustafa Kanat, Nadir Goksugur, Ali Haydar Parlak   +2 more
doaj   +2 more sources

ANCA associated vasculitis: experience of a tertiary care referral center

Brazilian Journal of Nephrology, 2018
Background and objectives: Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis is a small vessel vasculitis with insufficient epidemiologic estimates in the United States.
Rafia Chaudhry, Anum Bilal, Adam Austin, Swati Mehta, Loay Salman, Llewellyn Foulke, Paul Feustel, Roman Zuckerman, Arif Asif   +8 more
doaj   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

JEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato, Paolo Gisondi, Giampiero Girolomoni   +2 more
wiley   +1 more source

[Systemic ANCA-associated vasculitis--diagnosis and therapy]

, 2008
ANCA-associated vasculitis represents a group of small-vessel vasculitides, including Wegener's granulomatosis, microscopic polyangiitis and the Churg-Strauss-syndrome.
Hess, Christof, Eisenberger, Ute
core   +1 more source