Results 71 to 80 of about 8,073,410 (232)
Genetics of ANCA-Associated Vasculitis
ANCA-associated vasculitis (AAV) is a group of disorders that is caused by inflammation affecting small blood vessels. AAV includes microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) renamed from Wegener’s granulomatosis, and ...
Paul Anthony Lyons +5 more
core +1 more source
Immnunopathology of ANCA-Associated Vasculitis.
During the past few years remarkable progress has been achieved in the understanding of the pathogenic mechanisms leading to vascular inflammation and injury in ANCA-associated vasulitides (AAV): Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and Churg Strauss syndrome (CSS).
ELENA, Csernok +2 more
openaire +3 more sources
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley +1 more source
Malignancy is increased in ANCA-associated vasculitis
Objective. In the light of previous reports of an association between malignancy and renal vasculitis, we aimed to investigate the association of malignancy in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, either Wegener’s ...
Pankhurst, Tanya +7 more
core +1 more source
A case of small vessel vasculitis
Anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis is the most common primary systemic small-vessel vasculitis occurring in adults. Although the etiology is not always known, the incidence of vasculitis is increasing, with a variability ...
Madhulika Mahashabde, Harshad Patil
doaj +1 more source
Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato +4 more
wiley +1 more source
Progress in pathogenesis and therapy of vasculitis syndrome [PDF]
血管炎症候群においては,ANCAの発見によりその発症機序,病態が明らかにされつつある.感染症などを契機としてTNFαなどの炎症性サイトカインが誘導され,それによって細胞膜表面に露出した細胞質内顆粒構成成分に結合したANCAは血管内皮細胞とも結合し,溶解酵素および活性酸素を放出して傷害することが明らかになっている.ANCAの産生についても細菌菌体成分との分子相同性が関与している可能性が示唆されている.治療については,The European Vasculitis Study Group (EUVAS ...
折口, 智樹 +5 more
core +1 more source
Pathogenesis of ANCA-Associated Vasculitis, an Update
Clinical observations, including a report of neonatal vasculitis occurring in a child born from a mother with anti-neutrophil cytoplasmic antibody directed to myeloperoxidase (MPO-ANCA)-associated vasculitis, suggest a pathogenic role for ANCA.
Cees G. M. Kallenberg +1 more
core +1 more source
Exercise‐Induced Vasculitis in a 12‐Year‐Old Child: A Case Report
ABSTRACT Exercise‐induced vasculitis (EIV), colloquially known as “Disney rash,” is a benign, self‐limited leukocytoclastic vasculitis of the lower extremities triggered by prolonged exertion in warm weather, well‐recognized in adults but underappreciated in children.
Beverly X. Yu +3 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source

