Results 81 to 90 of about 9,354,751 (270)

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

JEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato, Paolo Gisondi, Giampiero Girolomoni   +2 more
wiley   +1 more source

The Pathogenicity of BPI-ANCA in a Patient With Systemic Vasculitis

Frontiers in Immunology, 2019
Objective: ANCA associated vasculitis (AAV) is characterized by systemic necrotizing vasculitis with the presence of ANCA. Although BPI-ANCA is one of the atypical ANCAs and is occasionally seen in patients with vasculitis, the pathogenicity of BPI-ANCA ...
Sayo Takeda, Kanako Watanabe-Kusunoki, Daigo Nakazawa, Yoshihiro Kusunoki, Saori Nishio, Tatsuya Atsumi   +5 more
doaj   +1 more source

Data-driven subclassification of ANCA-associated vasculitis: model-based clustering of a federated international cohort.

The Lancet Rheumatology
BACKGROUND Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a heterogenous autoimmune disease. While traditionally stratified into two conditions, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), the ...
Karl Gisslander, Arthur White, Louis Aslett, Zdenka Hrušková, Peter Lamprecht, Jacek Musiał, Jamsheela Nazeer, James Ng, Declan O'Sullivan, Xavier Puéchal, Matthew Rutherford, Mårten Segelmark, Benjamin Terrier, Vladimir Tesař, M. Tesi, Augusto Vaglio, K. Wójcik, Mark A. Little, Aladdin J. Mohammad, Adrian Tassoni, Aladdin J. Mohammad, A. Bettiol, Arlette Tais, Arthur White, Augusto Vaglio, Benjamin Terrier, Beyza Yaman, C. Armstrong, Declan O'Sullivan, Dagmar Wandrei, Dipak Kalra, Fabian Schubach, François Dradin, G. Emmi, Giacomo Bagni, Gabriele Ihorst, Hannelore Aerts, Hicham Kardaoui, I. Mattioli, Iris Sengers, Jacek Musiał, Jennifer Scott, J. Mills, Julie Julie Power, Karl Gisslander, K. Wawrzycka-Adamczyk, Kris McGlinn, K. Wójcik, Louis Aslett, Lucy Hederman, Margaret Dunne, Marco A. Alba, Maria Christofidou, Mark A. Little, Mårten Segelmark, Matija Crnogorac, Matthew Rutherford, M. Tesi, Nathan Lea, Neil Basu, Peter Lamprecht, Peter Verhoeven, Raïssa de Boer, Richard Straka, Sabina Lichołai, S. Arnold, Vladimir Tesar, Xavier Puéchal, Zdenka Hruskova   +68 more
semanticscholar   +1 more source

[Systemic ANCA-associated vasculitis--diagnosis and therapy]

, 2008
ANCA-associated vasculitis represents a group of small-vessel vasculitides, including Wegener's granulomatosis, microscopic polyangiitis and the Churg-Strauss-syndrome.
Hess, Christof, Eisenberger, Ute
core   +1 more source

Classification Criteria for ANCA Associated Vasculitis – Ready for Prime Time?

Current Rheumatology Reports
This review aims to summarize the evolution and recent developments in the classification of ANCA associated vasculitis (AAV) and to summarize evaluations of the 2022 ACR/EULAR classification criteria of AAV in several cohorts.
Jens Rathmann, A. Mohammad
semanticscholar   +1 more source

Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis

Scientific Reports, 2021
Neutrophils form neutrophil extracellular traps (NETs), which are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Recent reports suggest that platelets stimulated via toll-like receptor (TLR) pathways can induce NETs formation. However,
Kotaro Matsumoto, H. Yasuoka, K. Yoshimoto, Katsuya Suzuki, T. Takeuchi   +4 more
semanticscholar   +1 more source

Approach to Surgical Repair of Nasal Septal Perforation

The Laryngoscope, EarlyView.
Nasal septal perforation repair remains technically demanding, with technique selection guided by perforation size, location, etiology, and patient risk factors. Contemporary evidence supports mucosal advancement flaps for small perforations (< 1 cm), bilateral advancement with interposition grafting or trilayer temporoparietal fascia–polydioxanone ...
Nicole J. Reynoso, Andrea M. Park, P. Daniel Knott   +2 more
wiley   +1 more source

Mechanisms of vasculitis:How pauci-immune is ANCA-associated renal vasculitis?

, 2007
Both the innate and the acquired immune system are involved in the pathophysiology of renal vasculitis. However, anti-neutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis is characterized by a 'pauci-immune' pattern of immunofluorescence ...
Heeringa, P., Heeringa, P.; id_orcid, van Paassen, P., Tervaert, J. W. Cohen   +3 more
core   +1 more source

Urinary CD4+ T Cells Predict Renal Relapse in ANCA-Associated Vasculitis

Journal of the American Society of Nephrology
Visual Abstract Significance Statement Early identification of patients at risk of renal flares in ANCA vasculitis is crucial. However, current clinical parameters have limitations in predicting renal relapse accurately.
L. Prskalo, C. Skopnik, N. Goerlich, P. Freund, Leonie Wagner, Emil Grothgar, P. Mirkheshti, J. Klocke, Janis Sonnemann, D. Metzke, Udo Schneider, F. Hiepe, K. Eckardt, Alan D. Salama, M. Bieringer, Adrian Schreiber, P. Enghard   +16 more
semanticscholar   +1 more source

Diagnostic Delay in Eosinophilic Granulomatosis With Polyangiitis: Clinical Predictors and Implications for Earlier Recognition

Allergy, EarlyView.
This study aimed to assess diagnostic delay among patients with eosinophilic granulomatosis with polyangiitis (EGPA) and identify clinical characteristics associated with delayed recognition. EGPA diagnosis was delayed by nearly five years from symptom onset in this single‐center cohort.
Vani Mulkareddy, Kalena Liu, Shreya Mandloi, Kelsey Limage, Samuel R. Shing, Gurston G. Nyquist, Jessica Most, David Kennedy, Elina Toskala, Damaris Pena‐Evertz   +9 more
wiley   +1 more source