Results 101 to 110 of about 8,073,410 (232)
ANCA-associated vasculitis in childhood: recent advances [PDF]
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic polyangiitis (MPA) and eosinophilic ...
Mariagrazia Catanoso +61 more
core +1 more source
Anticuerpos anticitoplasma del neutrófilo en la clasificación de las vasculitis sistémicas
La detección de los anticuerpos anticitoplasma del neutrófilo (ANCA) constituye el diagnóstico inmunológico de las vasculitis sistémicas. Este trabajo estuvo dirigido a probar la utilidad clínica del método de inmunofluorescencia indirecta (IFI) sobre ...
Elena Kokuina +3 more
doaj
Respiratory manifestations of ANCA‐associated vasculitis
AbstractBackgroundThe prevalence of pulmonary manifestations of ANCA‐associated vasculitis (AAV) is not well understood. This study describes the prevalence of respiratory complications of AAV detected via imaging in patients presenting to a secondary renal centre and describes the associations with mortality.Methods105 patients with AAV were ...
Greenan, Kerry +7 more
openaire +3 more sources
Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann +4 more
wiley +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
The Th1 and Th2 paradigm in ANCA-associated vasculitis
In the pathogenesis of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitis, T cell contribution is indicated by T cell-dependent ANCA production combined with the presence of T cells in inflammatory infiltrates.
Stegeman, C A; id_orcid +4 more
core +1 more source
Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitides are autoimmune diseases with multisystem manifestations. We report the case of a 55-year-old Asian man with a history of cigarette smoking who presented with ischemic lesions of the ...
Naushad Abid, Hamzah Naushad Siddiqui
doaj +1 more source
Background Wegener's Granulomatosis and Microscopic Polyangiitis are life-threatening systemic necrotizing vasculitides of unknown aetiology. The appearance of circulating antibodies to neutrophil cytoplasmic antigens (ANCA) is strongly associated with ...
Sarvestani Ghafar +8 more
doaj +1 more source
A Rare Case of COPA Syndrome: Multisystem Relapse and Fatal Septic Complication
A 45‐year‐old man with a history of recurrent respiratory failure, arthritis and renal dysfunction was diagnosed with COPA syndrome through genetic testing after years of progressive interstitial lung disease and immune‐mediated manifestations. He initially responded to immunosuppressive therapy but relapsed after treatment discontinuation, developing ...
Flavia Castro Velasco Fernandes +7 more
wiley +1 more source

