Results 31 to 40 of about 28,298 (296)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Thermal-Hydraulic Modeling of Oil-Immersed Motor Pump
Applied Sciences, 2023 The integrated design of the motor and axial piston pump eliminates the coupling structure, resulting in a compact and lightweight motor-pump structure. The challenge of motors overheating has always been a major concern.
Junqiang Shi +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
LubricantsPlanetary gear is the mainstream deceleration transmission device, and its derivative form of high contact ratio internal gear adopts the structure of full internal meshing.
Xiaomeng Chu, Zhijun Gao, Jia Shen
doaj +1 more source
Stability and Churning in Medi-Cal and Healthy Families [PDF]
, 2008 This report examines enrollment patterns and gaps overall and for specific groups within Medi-Cal and Healthy Families, as well as medical costs after a gap.
Gerry Fairbrother, Joseph Schuchter
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Job Creation, Worker Churning, and Wages at Young Businesses [PDF]
, 2012 Prior research has established the important role of startups and fast-growing young businesses in job creation and employment growth in the U.S. economy (Haltiwanger, Jarmin, and Miranda, (2010)).
Erika McEntarfer +3 more
core
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Research on the Power Loss of High-Speed and High-Load Ball Bearing for Cryogenic Turbopump
Machines, 2022 This paper studies the lubrication characteristics of ball bearings for cryogenic turbopumps. First, the frictional coefficients between 440C and a Ag coating, 440C and solid PTFE (polytetrafluoroethylene), and 440C and a PTFE coating in LN2 (liquid ...
Wenhu Zhang +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source