Results 61 to 70 of about 4,061,646 (326)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Power loss analysis in altered tooth-sum spur gearing

MATEC Web of Conferences, 2018
The main cause of power loss or dissipation of heat in case of meshed gears is due to friction existing between gear tooth mesh and is a major concern in low rotational speed gears, whereas in case of high operating speed the power loss taking place due ...
Sachidananda H. K., Raghunandana K., Shivamurthy B.   +2 more
doaj   +2 more sources

Flow Field Analysis of Spur Gear Meshing Period Under the State of Oil-immersion Lubrication

Jixie chuandong, 2018
In order to make clear the mechanism of oil churning loss of gearbox and to further improve the efficiency of gear transmission,the factors that effects on oil churning losses are studied.
Zhou Yajie, Wang Bin, Ling Jianhui
doaj  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Engineering Deformation and Failure in Diamond Triply Periodic Minimal Surface Lattices via 3D Wall‐Thickness Grading

Advanced Engineering Materials, EarlyView.
The work demonstrates that strategic wall‐thickness grading in diamond triply periodic minimal surface lattices enables precise tuning of deformation and failure behavior under compression. Different gradation patterns guide how and where the structure collapses, improving energy absorption or promoting controlled brittle failure.
Giovanni Rizza, Danilo Bruson, Manuela Galati, Luca Iuliano   +3 more
wiley   +1 more source

Experimental study on churning losses reduction for axial piston pumps

, 2018
Published by [Mainz ...
Li, Ying, Xu, Bing, Zhang, Junhui, Chen, Xia   +3 more
openaire   +2 more sources

Influence of the Lubricant Temperature of Splashed Lubricated Worm Gearbox on Churning Power Losses

ITEGAM-JETIA
The primary goal of lubricating a worm gearbox is to encourage sliding between teeth, which lowers the coefficient of friction and regulates the temperature rise brought on by rolling and sliding friction. Due to both non-load-dependent and load-
Hardik G Chothani, D.J. Marsonia, N.N. Jadeda, S.H. Zala   +3 more
doaj   +1 more source

Outdoor test stand performance of a convertible engine with variable inlet guide vanes for advanced rotorcraft propulsion [PDF]

A variable inlet guide van (VIGV) type convertible engine that could be used to power future high-speed rotorcraft was tested on an outdoor stand. The engine ran stably and smoothly in the turbofan, turboshaft, and dual (combined fan and shaft) power ...
Mcardle, Jack G.
core   +1 more source

CFD Simulations and Experiments for Reduction of Oil Churning Loss and Windage Loss on Aeroengine Transmission Gears

, 2013
In recent years, the demand for power generation capacity has increased considerably due to the electric drive of air conditioners and so on in the engines of civil aircraft.
Hidenori Arisawa, M. Nishimura, Hideyuki Imai, Kenichiro Tanaka, T. Goi   +4 more
semanticscholar   +1 more source