Results 11 to 20 of about 33,318 (283)
Intestinal cholesterol absorption involves the chylomicron and HDL pathways and is dependent on microsomal triglyceride transfer protein (MTP) and ABCA1, respectively.
Jahangir Iqbal+3 more
doaj +2 more sources
Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice. [PDF]
Endotoxemia stimulates many physiologic responses including disturbances in lipid metabolism. We hypothesized that this lipemia may be part of a defensive mechanism by which the body combats the toxic effects of circulating endotoxin.
Hobart W. Harris+3 more
openalex +2 more sources
The surface coat of chylomicrons: lipid chemistry
Chylomicrons from the thoracic duct lymph of dogs fed corn oil were isolated by centrifugation and disrupted by either freezing and thawing or rotary evaporation and rehydration.
D.B. Zilversmit
doaj +2 more sources
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat. [PDF]
ABSTRACT The primary features of the alpha‐gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha‐1,3‐galactose. (ii) In the USA, this IgE ab is induced by bites of the tick Amblyomma americanum. (iii) The anaphylactic reactions to food derived from non‐primate mammals
Platts-Mills TAE+3 more
europepmc +2 more sources
Chylomicron metabolism during dietary-induced hypercholesterolemia in dogs.
The metabolism of [1-3H]retinol- and [4-14C]cholesterol-labeled chylomicrons was studied in normal and cholesterol-fed dogs in order to estimate the relative contribution of chylomicron remnant cholesterol to diet-induced hypercholesterolemia. The plasma
G W Melchior, R W Mahley, D K Buckhold
doaj +2 more sources
Oxidized lipids in the diet are a source of oxidized lipid in chylomicrons of human serum. [PDF]
We examined whether oxidized lipids in the diet determine the levels of oxidized lipid in human postprandial serum chylomicrons. After we fed subjects control corn oil containing low quantities of oxidized lipid, the levels of conjugated dienes in the ...
Ilona Staprãns+4 more
openalex +2 more sources
Hepatic uptake of chylomicron remnants
Chylomicrons are formed in the intestine and transport dietary triglyceride to peripheral tissues and cholesterol to the liver. The enzyme lipoprotein lipase, with apolipoprotein (apo)C-II as a co-factor, hydrolyzes chylomicron triglyceride allowing the delivery of free fatty acids to muscle and adipose tissue.
A D Cooper
openalex +4 more sources
Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption
Background: Lymphatic vessels are responsible for tissue drainage, and their malfunction is associated with chronic diseases. Lymph uptake occurs via specialized open cell-cell junctions between capillary lymphatic endothelial cells (LECs), whereas ...
G. Zarkada+21 more
semanticscholar +1 more source
Although tissue uptake of fatty acids from chylomicrons is primarily via lipoprotein lipase (LpL) hydrolysis of triglycerides (TGs), studies of patients with genetic LpL deficiency suggest additional pathways deliver dietary lipids to tissues. Despite an
Ainara G. Cabodevilla+8 more
semanticscholar +1 more source
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince+30 more
wiley +1 more source