Results 1 to 10 of about 26,251 (228)

Unpacking and understanding the impact of proprotein convertase subtilisin/kexin type 9 inhibitors on apolipoprotein B metabolism [PDF]

, 2017
No abstract ...
Packard, Chris J.
core   +1 more source

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway [PDF]

, 2016
Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown ...
Botham, K M, Latham Birt, S H, Purcell, R, Wheeler-Jones, C P D   +3 more
core   +1 more source

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. [PDF]

, 2013
The secretory pathway of eukaryotic cells packages cargo proteins into COPII-coated vesicles for transport from the endoplasmic reticulum (ER) to the Golgi.
Adams, Elizabeth, Bai, Yongsheng, Baines, Andrea, Bajaj, Kanika, Chen, Xiao-Wei, Ginsburg, David, Lin, Jiandie, Liu, Hui-Hui, Ma, Danjun, Meng, Zhuo-Xian, Sartor, Maureen A, Schekman, Randy, Wang, He, Yi, Zhengping, Young, Stephen G, Yu, Genggeng, Zhang, Bin, Zhang, Pengcheng   +17 more
core   +1 more source

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation. [PDF]

, 2012
ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury.
Altman, Robin, Budamagunta, Madhu S., den Hartigh, Laura J., Hutchinson, Romobia, Lagerstedt, Jens,, Lund University., Lund University., Petrlova, Jitka,, Rutledge, John C., Tetali, Sarada D., Voss, John C.   +10 more
core   +3 more sources

A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER[S]

Journal of Lipid Research, 2010
Dietary lipid absorption is dependent on chylomicron production whose rate-limiting step across the intestinal absorptive cell is the exit of chylomicrons from the endoplasmic reticulum (ER) in its ER-to-Golgi transport vesicle, the prechylomicron ...
Shahzad Siddiqi, Umair Saleem, Nada A. Abumrad, Nicholas O. Davidson, Judith Storch, Shadab A. Siddiqi, Charles M. Mansbach, II   +6 more
doaj   +1 more source

Apolipoprotein A-IV: a protein intimately involved in metabolism

Journal of Lipid Research, 2015
The purpose of this review is to summarize our current understanding of the physiological roles of apoA-IV in metabolism, and to underscore the potential for apoA-IV to be a focus for new therapies aimed at the treatment of diabetes and obesity-related ...
Fei Wang, Alison B. Kohan, Chun-Min Lo, Min Liu, Philip Howles, Patrick Tso   +5 more
doaj   +1 more source

Validation of a Method to Prepare Artificial Chylomicron Remnant-like Particles [PDF]

, 2010
1 página. Proceedings and Abstracts of the 2nd International Symposium on Chylomicrons in Disease-2 (ISCD2)Resumen póster.Peer ...
Arndt, Mirjam, Bolvardi, Hamid, Emmerlich, Jens, Mráz, Stanislav, Rudigier, Helmut, Schneider, Jochen M.   +5 more
core   +1 more source

Sec24C is required for docking the prechylomicron transport vesicle with the Golgi

Journal of Lipid Research, 2010
The rate-limiting step in the transit of dietary fat across the intestinal absorptive cell is its exit from the endoplasmic reticulum (ER) in a specialized ER-to-Golgi transport vesicle, the prechylomicron transport vesicle (PCTV).
Shahzad Siddiqi, Shadab A. Siddiqi, Charles M. Mansbach, II   +2 more
doaj   +1 more source

Role of the enterocyte in fructose-induced hypertriglyceridaemia [PDF]

, 2017
Dietary fructose has been linked to an increased post-prandial triglyceride (TG) level; which is an established independent risk factor for cardiovascular disease. Although much research has focused on the effects of fructose consumption on liver-derived
A. Margot Umpleby, Bantle, Barbara A. Fielding, Bjorkman, Chong, Federico, Julie A. Lovegrove, Kim G. Jackson, Knuth, Le, Prentice, Simon Steenson, Vos, White   +13 more
core   +1 more source

Fatty acid esterification and chylomicron formation during fat absorption: 2. Phospholipids

Journal of Lipid Research, 1963
Studies were conducted on the over-all fatty acid specificity of the mechanisms involved in chylomicron lecithin formation during fat absorption in the rat.
Malcolm Whyte, Arthur Karmen, DeWitt S. Goodman   +2 more
doaj   +1 more source