Results 21 to 30 of about 17,950 (189)

N-3 fatty acids and chylomicron metabolism in the rat

Journal of Lipid Research, 1997
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris, B E Hustvedt, E Hagen, M H Green, G Lu, C A Drevon   +5 more
doaj   +1 more source

Chylomicrons promote intestinal absorption of lipopolysaccharides

Journal of Lipid Research, 2009
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides (LPS) from the gut microflora, which might contribute to various inflammatory disorders.
Sarbani Ghoshal, Jassir Witta, Jian Zhong, Willem de Villiers, Erik Eckhardt   +4 more
doaj   +1 more source

Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E.

Journal of Lipid Research, 1993
The consequences of hepatic lipase treatment of chylomicron remnants were studied. Rats were fed corn oil to induce production and secretion of chylomicrons and were then injected with polyclonal antiserum raised against hepatic lipase to specifically ...
DL Brasaemle, K Cornely-Moss, A Bensadoun   +2 more
doaj   +1 more source

Differences in the processing of chylomicron remnants and beta-VLDL by macrophages.

Journal of Lipid Research, 1990
To gain a detailed understanding of those factors that govern the processing of dietary-derived lipoprotein remnants by macrophages we examined the uptake and degradation of rat triacylglycerol-rich chylomicron remnants and rat cholesterol-rich beta-very
JL Ellsworth, LG Fong, FB Kraemer, AD Cooper   +3 more
doaj   +1 more source

Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis

Journal of Lipid Research, 1982
To ascertain whether chylomicron constituents would be transferred to low density lipoprotein (LDL, d 1.019-1.063 g/ml) and high density lipoprotein (HDL, d 1.063-1.21 g/ml) density fractions during lipolysis in the absence of other lipoproteins, the in ...
E J Schaefer, M G Wetzel, G Bengtsson, R O Scow, H B Brewer, Jr, T Olivecrona   +5 more
doaj   +1 more source

Intestinal basolateral lipid substrate transport is linked to chylomicron secretion and is regulated by apoC-III

Journal of Lipid Research, 2019
Chylomicron metabolism is critical for determining plasma levels of triacylglycerols (TAGs) and cholesterol, both of which are risk factors for CVD.
Diana Li, Cayla N. Rodia, Zania K. Johnson, Minkyung Bae, Angelika Muter, Amy E. Heussinger, Nicholas Tambini, Austin M. Longo, Hongli Dong, Ji-Young Lee, Alison B. Kohan   +10 more
doaj   +1 more source

Removal of chylomicron remnants in transgenic mice overexpressing normal and membrane-anchored hepatic lipase

Journal of Lipid Research, 2005
The LDL receptor and the LDL receptor-related protein (LRP) mediate the removal of chylomicron remnants. The LRP pathway involves sequestration of particles in the space of Disse.
Sung-Joon Lee, Sujata Kadambi, Kenneth C-W. Yu, Christopher David, Salman Azhar, Allen D. Cooper, Sungshin Y. Choi   +6 more
doaj   +1 more source

Low and high responders to pharmacological doses of β-carotene: proportion in the population, mechanisms involved and consequences on β-carotene metabolism

Journal of Lipid Research, 1998
The aim of this study was to assess the interindividual variability of chylomicron β-carotene response to a pharmacological load of β-carotene in the population, to identify the mechanisms responsible for this variability, and to evaluate its ...
Patrick Borel, Pascal Grolier, Nadia Mekki, Yves Boirie, Yvanne Rochette, Brigitte Le Roy, Marie C. Alexandre-Gouabau, Denis Lairon, Véronique Azais-Braesco   +8 more
doaj   +1 more source

Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model

Lipids in Health and Disease, 2023
Background There is increasing evidence that dietary fat, especially saturated fat, promotes the translocation of lipopolysaccharide (LPS) via chylomicron production in the gut.
Monic M. M. Tomassen, Coen Govers, A. Paul Vos, Nicole J. W. de Wit   +3 more
doaj   +1 more source

New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases

Frontiers in Pharmacology, 2023
The incidence of obesity and associated metabolic diseases is increasing globally, adversely affecting human health. Dietary fats, especially triglycerides, are an important source of energy for the body, and the intestine absorbs lipids through a series
Xiaojing Li, Qiaohong Liu, Yuqing Pan, Si Chen, Yu Zhao, Yiyang Hu, Yiyang Hu   +6 more
doaj   +1 more source