Results 21 to 30 of about 19,423 (204)

New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases

Frontiers in Pharmacology, 2023
The incidence of obesity and associated metabolic diseases is increasing globally, adversely affecting human health. Dietary fats, especially triglycerides, are an important source of energy for the body, and the intestine absorbs lipids through a series
Xiaojing Li, Qiaohong Liu, Yuqing Pan, Si Chen, Yu Zhao, Yiyang Hu, Yiyang Hu   +6 more
doaj   +1 more source

Chylomicron catabolism differs between Hooded and albino laboratory rats.

Journal of Lipid Research, 1982
To extend previous reports that some aspects of lipid metabolism are different between Hooded and albino strains of laboratory rats, thoracic duct lymph chylomicrons were collected and their composition and metabolism were compared in this study ...
F Jeffery, T G Redgrave
doaj   +1 more source

Rapid initial removal of chylomicron remnants by the mouse liver does not require hepatically localized apolipoprotein E

Journal of Lipid Research, 2000
Apolipoprotein E (apoE) is a ligand for the low density lipoprotein receptor (LDLR) and the low density lipoprotein receptor-related protein (LRP). The aim of the present study was to clarify the role of hepatically localized apoE in the rapid initial ...
Kenneth C-W. Yu, Yuan Jiang, Wei Chen, Allen D. Cooper   +3 more
doaj   +1 more source

Apolipoprotein E enrichment of immuno-separated chylomicron and chylomicron remnants following saturated fatty acids

, 2006
Aim: We examined the effect of meat fatty acids on lipid and apolipoprotein concentrations of very low density lipoprotein (VLDL) and chylomicron/chylomicron remnants in lipid fractions with a Svedberg flotation rate (S-f) 60-400 and S-f 20-60.
Wolstencroft, E.J., Bateman, P.A., Yaqoob, P., Jackson, K.G., Williams, C.M.   +4 more
core   +1 more source

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma

Journal of Lipid Research, 1998
Triglyceride-rich lipoproteins (TRLs) that are modified during alimentary lipemia and their remnants are indicated to play an important role in the development of atherosclerosis.
Johan Björkegren, Fredrik Karpe, Ross W. Milne, Anders Hamsten   +3 more
doaj   +1 more source

Apolipoprotein CIII predicts cardiovascular events in patients with coronary artery disease: a prospective observational study

Lipids in Health and Disease, 2020
Background Apolipoprotein CIII (apoCIII) is associated with triglyceride-rich lipoprotein metabolism and has emerged as independent marker for risk of cardiovascular disease.
Julius L. Katzmann, Christian M. Werner, Tatjana Stojakovic, Winfried März, Hubert Scharnagl, Ulrich Laufs   +5 more
doaj   +1 more source

Effects of cholesterol in chylomicron remnant models of lipid emulsions on apoE-mediated uptake and cytotoxicity of macrophages

Journal of Lipid Research, 2005
Chylomicron remnants have been suggested to be involved in the development of atherosclerosis. To investigate the mechanisms of chylomicron remnant-induced atherosclerosis, we prepared cholesterol (Chol)-containing emulsion particles as models for ...
Atsushi Sakurai, Shin-ya Morita, Kyoko Wakita, Yuko Deharu, Minoru Nakano, Tetsurou Handa   +5 more
doaj   +1 more source

Chylomicron metabolism in rats: lipolysis, recirculation of triglyceride-derived fatty acids in plasma FFA, and fate of core lipids as analyzed by compartmental modelling

Journal of Lipid Research, 1996
Chylomicrons labeled in vivo with [14C]oleic acid (primarily in triglycerides (TG), providing a tracer for lipolysis) and [3H]retinol (primarily in ester form, providing a tracer for the corelipids) were injected into rats.
M Hultin, R Savonen, T Olivecrona
doaj   +1 more source

VLDL receptor mediates the uptake of human chylomicron remnants in vitro.

Journal of Lipid Research, 1996
The VLDL receptor has been described as a new member of the LDL receptor supergene family that specifically binds VLDL in vitro via apolipoprotein E and lipoprotein lipase.
A Niemeier, M Gàfvels, J Heeren, N Meyer, B Angelin, U Beisiegel   +5 more
doaj   +1 more source

The induction of macrophages foam cell formation by chylomicron remnants

, 2007
The accumulation of foam cells in the artery wall causes fatty streaks, the first lesions in atherosclerosis. LDL (low-density lipoprotein) plays a major role in foam cell formation, although prior oxidation of the particles is required.
De Pascale, C., Moore, E.H., Botham, K.M., Bejta, F.   +3 more
core   +1 more source