Results 11 to 20 of about 26,251 (228)
Journal of Lipid Research, 1997 The size of cholesterol-rich lipoprotein particles is a strong determinant of whether they may be deposited in the arterial wall and by this become potentially atherogenic. This study deals with the in vivo transformation of larger-sized chylomicrons and
F Karpe +3 more
doaj +4 more sources
Journal of Lipid Research, 2019 Chylomicron metabolism is critical for determining plasma levels of triacylglycerols (TAGs) and cholesterol, both of which are risk factors for CVD.
Diana Li, Minkyung Bae
exaly +3 more sources
The pathophysiology of intestinal lipoprotein production [PDF]
Frontiers in Physiology, 2015 Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that ...
Antonina eGiammanco +3 more
doaj +4 more sources
Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta [PDF]
European Journal of Pharmacology, 1998 The effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta were studied in vitro. Chylomicrons and chylomicron remnants were prepared in vivo. Aortic rings were incubated with the lipoproteins for 45 min before the vessels were constricted with phenylephrine and concentration relaxation response curves ...
Grieve, David +3 more
openaire +6 more sources
The chylomicron saga: time to focus on postprandial metabolism
Frontiers in EndocrinologySince statins have had such tremendous therapeutic success over the last three decades, the field of atherosclerosis has become somewhat LDL-centric, dismissing the relevance of triglycerides (TG), particularly chylomicrons, in atherogenesis. Nonetheless,
Alejandro Gugliucci
exaly +3 more sources
The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta [PDF]
Atherosclerosis, 1998 Jonathan Elliott, Kathleen M Botham
exaly +2 more sources
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
The Biogenesis of Chylomicrons [PDF]
Annual Review of Physiology, 2010 The absorption of dietary fat is of increasing concern given the rise of obesity not only in the United States but throughout the developed world. This review explores what happens to dietary fat within the enterocyte. Absorbed fatty acids and monoacylglycerols are required to be bound to intracellular proteins and/or to be rapidly converted to ...
Charles M, Mansbach, Shadab A, Siddiqi
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Journal of Lipid Research, 1990 To characterize lipoprotein uptake by macrophages, we studied J774 murine macrophage-derived cells. Uptake of 125I-labeled beta-VLDL and 125I-labeled chylomicron remnants was saturable, specific, and of high affinity.
J L Ellsworth, A D Cooper, F B Kraemer
doaj +1 more source
Comparison of the metabolism of chylomicrons and chylomicron remnants by the perfused liver [PDF]
Biochemical Journal, 1978 1. The hepatic metabolism of chylomicrons and chylomicron remnants was compared after adding approximately equal numbers of each lipoprotein particle to the perfusate of isolated livers. 2. At least 40% of the added remnants were metabolized by the liver compared with less than 3% for chylomicrons. 3.
R S, Gardner, P A, Mayes
openaire +2 more sources