Results 11 to 20 of about 17,950 (189)
Journal of Lipid Research, 1997 The size of cholesterol-rich lipoprotein particles is a strong determinant of whether they may be deposited in the arterial wall and by this become potentially atherogenic. This study deals with the in vivo transformation of larger-sized chylomicrons and
F Karpe +3 more
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The Biogenesis of Chylomicrons [PDF]
Annual Review of Physiology, 2010 The absorption of dietary fat is of increasing concern given the rise of obesity not only in the United States but throughout the developed world. This review explores what happens to dietary fat within the enterocyte. Absorbed fatty acids and monoacylglycerols are required to be bound to intracellular proteins and/or to be rapidly converted to ...
Charles M, Mansbach, Shadab A, Siddiqi
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Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Journal of Lipid Research, 1990 To characterize lipoprotein uptake by macrophages, we studied J774 murine macrophage-derived cells. Uptake of 125I-labeled beta-VLDL and 125I-labeled chylomicron remnants was saturable, specific, and of high affinity.
J L Ellsworth, A D Cooper, F B Kraemer
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Comparison of the metabolism of chylomicrons and chylomicron remnants by the perfused liver [PDF]
Biochemical Journal, 1978 1. The hepatic metabolism of chylomicrons and chylomicron remnants was compared after adding approximately equal numbers of each lipoprotein particle to the perfusate of isolated livers. 2. At least 40% of the added remnants were metabolized by the liver compared with less than 3% for chylomicrons. 3.
R S, Gardner, P A, Mayes
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Journal of Nutritional Science, 2012 Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
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Role of hepatic lipase in the uptake and processing of chylomicron remnants in rat liver.
Journal of Lipid Research, 1994 The participation of hepatic lipase in the initial uptake and processing of chylomicron remnants was studied in the isolated, perfused rat liver. Hepatic lipase activity was either reduced by preperfusion of livers with heparin or inhibited with specific
S Shafi +3 more
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Metabolism of chylomicrons by the isolated rat liver
Journal of Lipid Research, 1967 Isolated livers perfused with washed corn oil chylomicrons labeled in vivo with palmitic acid-1-14C removed a large proportion of the chylomicrons. Slices from these livers oxidized chylomicron fatty acid esters to both carbon dioxide and acetoacetate ...
Joseph A. Ontko, D.B. Zilversmit
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The Chylomicron: Relationship to Atherosclerosis [PDF]
International Journal of Vascular Medicine, 2012 The B-containing lipoproteins are the transporters of cholesterol, and the evidence suggests that the apo B48-containing postprandial chylomicron particles and the triglyceride-rich very low density lipoprotein (VLDL) particles play an important part in the development of the plaque both directly and indirectly by their impact on LDL composition.
Gerald H. Tomkin, Daphne Owens
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Journal of Lipid Research, 1992 The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle +4 more
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