Results 11 to 20 of about 19,423 (204)

Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E.

Journal of Lipid Research, 1993
The consequences of hepatic lipase treatment of chylomicron remnants were studied. Rats were fed corn oil to induce production and secretion of chylomicrons and were then injected with polyclonal antiserum raised against hepatic lipase to specifically ...
DL Brasaemle, K Cornely-Moss, A Bensadoun   +2 more
doaj   +3 more sources

Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model

Lipids in Health and Disease, 2023
Background There is increasing evidence that dietary fat, especially saturated fat, promotes the translocation of lipopolysaccharide (LPS) via chylomicron production in the gut.
Monic M. M. Tomassen, Coen Govers, A. Paul Vos, Nicole J. W. de Wit   +3 more
doaj   +2 more sources

The intracellular chylomicron highway: novel insights into chylomicron biosynthesis, trafficking, and secretion [PDF]

Current Opinion in Lipidology
Purpose of review Chylomicron biosynthesis plays a vital role in supplying essential lipids and lipid soluble vitamins to peripheral tissues for various functions. Despite this, the intracellular synthesis, trafficking, and secretion of chylomicrons remains only partly understood.
Visser, Ankia, Hussain, M. Mahmood, Kuivenhoven, Jan Albert   +2 more
openaire   +3 more sources

Regulation of the hepatic removal of chylomicron remnants and beta-very low density lipoproteins in the rat.

Journal of Lipid Research, 1992
The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle, F Rinninger, J Greeve, H Greten, E Windler   +4 more
doaj   +1 more source

N-3 fatty acids and chylomicron metabolism in the rat

Journal of Lipid Research, 1997
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris, B E Hustvedt, E Hagen, M H Green, G Lu, C A Drevon   +5 more
doaj   +1 more source

Chylomicrons promote intestinal absorption of lipopolysaccharides

Journal of Lipid Research, 2009
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides (LPS) from the gut microflora, which might contribute to various inflammatory disorders.
Sarbani Ghoshal, Jassir Witta, Jian Zhong, Willem de Villiers, Erik Eckhardt   +4 more
doaj   +1 more source

Differences in the processing of chylomicron remnants and beta-VLDL by macrophages.

Journal of Lipid Research, 1990
To gain a detailed understanding of those factors that govern the processing of dietary-derived lipoprotein remnants by macrophages we examined the uptake and degradation of rat triacylglycerol-rich chylomicron remnants and rat cholesterol-rich beta-very
JL Ellsworth, LG Fong, FB Kraemer, AD Cooper   +3 more
doaj   +1 more source

Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis

Journal of Lipid Research, 1982
To ascertain whether chylomicron constituents would be transferred to low density lipoprotein (LDL, d 1.019-1.063 g/ml) and high density lipoprotein (HDL, d 1.063-1.21 g/ml) density fractions during lipolysis in the absence of other lipoproteins, the in ...
E J Schaefer, M G Wetzel, G Bengtsson, R O Scow, H B Brewer, Jr, T Olivecrona   +5 more
doaj   +1 more source

Removal of chylomicron remnants in transgenic mice overexpressing normal and membrane-anchored hepatic lipase

Journal of Lipid Research, 2005
The LDL receptor and the LDL receptor-related protein (LRP) mediate the removal of chylomicron remnants. The LRP pathway involves sequestration of particles in the space of Disse.
Sung-Joon Lee, Sujata Kadambi, Kenneth C-W. Yu, Christopher David, Salman Azhar, Allen D. Cooper, Sungshin Y. Choi   +6 more
doaj   +1 more source

Low and high responders to pharmacological doses of β-carotene: proportion in the population, mechanisms involved and consequences on β-carotene metabolism

Journal of Lipid Research, 1998
The aim of this study was to assess the interindividual variability of chylomicron β-carotene response to a pharmacological load of β-carotene in the population, to identify the mechanisms responsible for this variability, and to evaluate its ...
Patrick Borel, Pascal Grolier, Nadia Mekki, Yves Boirie, Yvanne Rochette, Brigitte Le Roy, Marie C. Alexandre-Gouabau, Denis Lairon, Véronique Azais-Braesco   +8 more
doaj   +1 more source