Results 31 to 40 of about 17,950 (189)

Rapid initial removal of chylomicron remnants by the mouse liver does not require hepatically localized apolipoprotein E

Journal of Lipid Research, 2000
Apolipoprotein E (apoE) is a ligand for the low density lipoprotein receptor (LDLR) and the low density lipoprotein receptor-related protein (LRP). The aim of the present study was to clarify the role of hepatically localized apoE in the rapid initial ...
Kenneth C-W. Yu, Yuan Jiang, Wei Chen, Allen D. Cooper   +3 more
doaj   +1 more source

Chylomicron catabolism differs between Hooded and albino laboratory rats.

Journal of Lipid Research, 1982
To extend previous reports that some aspects of lipid metabolism are different between Hooded and albino strains of laboratory rats, thoracic duct lymph chylomicrons were collected and their composition and metabolism were compared in this study ...
F Jeffery, T G Redgrave
doaj   +1 more source

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma

Journal of Lipid Research, 1998
Triglyceride-rich lipoproteins (TRLs) that are modified during alimentary lipemia and their remnants are indicated to play an important role in the development of atherosclerosis.
Johan Björkegren, Fredrik Karpe, Ross W. Milne, Anders Hamsten   +3 more
doaj   +1 more source

Chylomicron metabolism in rats: lipolysis, recirculation of triglyceride-derived fatty acids in plasma FFA, and fate of core lipids as analyzed by compartmental modelling

Journal of Lipid Research, 1996
Chylomicrons labeled in vivo with [14C]oleic acid (primarily in triglycerides (TG), providing a tracer for lipolysis) and [3H]retinol (primarily in ester form, providing a tracer for the corelipids) were injected into rats.
M Hultin, R Savonen, T Olivecrona
doaj   +1 more source

Apolipoprotein CIII predicts cardiovascular events in patients with coronary artery disease: a prospective observational study

Lipids in Health and Disease, 2020
Background Apolipoprotein CIII (apoCIII) is associated with triglyceride-rich lipoprotein metabolism and has emerged as independent marker for risk of cardiovascular disease.
Julius L. Katzmann, Christian M. Werner, Tatjana Stojakovic, Winfried März, Hubert Scharnagl, Ulrich Laufs   +5 more
doaj   +1 more source

Effects of cholesterol in chylomicron remnant models of lipid emulsions on apoE-mediated uptake and cytotoxicity of macrophages

Journal of Lipid Research, 2005
Chylomicron remnants have been suggested to be involved in the development of atherosclerosis. To investigate the mechanisms of chylomicron remnant-induced atherosclerosis, we prepared cholesterol (Chol)-containing emulsion particles as models for ...
Atsushi Sakurai, Shin-ya Morita, Kyoko Wakita, Yuko Deharu, Minoru Nakano, Tetsurou Handa   +5 more
doaj   +1 more source

VLDL receptor mediates the uptake of human chylomicron remnants in vitro.

Journal of Lipid Research, 1996
The VLDL receptor has been described as a new member of the LDL receptor supergene family that specifically binds VLDL in vitro via apolipoprotein E and lipoprotein lipase.
A Niemeier, M Gàfvels, J Heeren, N Meyer, B Angelin, U Beisiegel   +5 more
doaj   +1 more source

A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) results in altered postprandial chylomicron triglyceride and retinyl palmitate response in normolipidemic carriers.

Journal of Lipid Research, 1996
An Asn291Ser mutation in exon 6 of the lipoprotein lipase gene (LPL) frequently occurs in Caucasians (2-4%) and results in a partial catalytic defect.
S N Pimstone, S M Clee, S E Gagné, L Miao, H Zhang, E A Stein, M R Hayden   +6 more
doaj   +1 more source

Role of the Gut in Diabetic Dyslipidemia

Frontiers in Endocrinology, 2020
Type 2 diabetes (T2D) is associated with increased risk of cardiovascular disease (CVD). In insulin resistant states such as the metabolic syndrome, overproduction and impaired clearance of liver-derived very-low-density lipoproteins and gut-derived ...
Priska Stahel, Changting Xiao, Avital Nahmias, Gary F. Lewis   +3 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source