Results 51 to 60 of about 19,423 (204)

Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta [PDF]

open access: yesEuropean Journal of Pharmacology, 1998
The effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta were studied in vitro. Chylomicrons and chylomicron remnants were prepared in vivo. Aortic rings were incubated with the lipoproteins for 45 min before the vessels were constricted with phenylephrine and concentration relaxation response curves ...
Grieve, David   +3 more
openaire   +4 more sources

Role of platelet factor Xa in chylomicron-prothrombin complexes induced platelet activation

open access: yes, 1995
The effects of chylomicron-prothrombin complexes on platelet activation, including platelet aggregation, serotonin release, arachidonic acid release and increases of platelet cytosolic [Ca2+]i were examined.
Öhlin, Ann-Kristin   +3 more
core   +1 more source

Critical Factors Involved in Intestinal Chylomicron Assembly

open access: yes, 2010
Assembly of intestinal chylomicron particles (lipid-protein complexes) is the fundamental mechanism by which we absorb dietary fat. Two intestinal lipid transporters, Cluster of Differentiation 36 (CD36) and fatty acid-binding protein 1 (FABP1), have ...
Webb, Jennifer P.
core   +1 more source

A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER[S]

open access: yesJournal of Lipid Research, 2010
Dietary lipid absorption is dependent on chylomicron production whose rate-limiting step across the intestinal absorptive cell is the exit of chylomicrons from the endoplasmic reticulum (ER) in its ER-to-Golgi transport vesicle, the prechylomicron ...
Shahzad Siddiqi   +6 more
doaj   +1 more source

Apolipoprotein A-IV: a protein intimately involved in metabolism

open access: yesJournal of Lipid Research, 2015
The purpose of this review is to summarize our current understanding of the physiological roles of apoA-IV in metabolism, and to underscore the potential for apoA-IV to be a focus for new therapies aimed at the treatment of diabetes and obesity-related ...
Fei Wang   +5 more
doaj   +1 more source

Lymph chylomicron formation during the inhibition of protein synthesis. Studies of chylomicron apoproteins

open access: yes, 1973
tein synthesis on chylomicron apoprotein composition was studied in mesenteric lymph fistula rats. Lymph was obtained from animals with impaired protein synthesis given intraperitoneal acetoxycycloheximide (ACH), a potent inhibitor of protein synthesis ...
R. M. Glickman, K. Kirsch
core  

Sec24C is required for docking the prechylomicron transport vesicle with the Golgi

open access: yesJournal of Lipid Research, 2010
The rate-limiting step in the transit of dietary fat across the intestinal absorptive cell is its exit from the endoplasmic reticulum (ER) in a specialized ER-to-Golgi transport vesicle, the prechylomicron transport vesicle (PCTV).
Shahzad Siddiqi   +2 more
doaj   +1 more source

Impaired chylomicron remnant clearance in familial combined hyperlipidemia.

open access: yes, 1993
Postprandial chylomicron remnant clearance was studied in six patients with familial combined hyperlipidemia (FCH) and seven control subjects by using an oral retinyl palmitate (RP) fat-loading test.
H Jansen   +5 more
core   +1 more source

Effect of increasing lipid loads on the ability of the endoplasmic reticulum to transport lipid to the Golgi

open access: yesJournal of Lipid Research, 2000
We have previously shown (Mansbach, C. M. and P. J. Nevin, 1998. J. Lipid Res. 39: 963–968) that after the development of a mass steady state with respect to triacylglycerol absorption in rats, the introduction of radiolabeled trioleoylglycerol, while ...
C.M. Mansbach, R. Dowell
doaj   +1 more source

Degradation of chylomicron remnants by macrophages occurs via phagocytosis

open access: yes, 1996
Chylomicron remnants bound to rabbit alveolar macrophages with high- affinity (K(d) = 3.3 ± 0.71 μg of protein/mL). The binding of chylomicron remnants was competitively inhibited in the presence of unlabeled remnants and to a lesser extent by ...
Gennat, HC (15495494)   +3 more
core  

Home - About - Disclaimer - Privacy