Results 51 to 60 of about 26,251 (228)

Role of the Gut in Diabetic Dyslipidemia

Frontiers in Endocrinology, 2020
Type 2 diabetes (T2D) is associated with increased risk of cardiovascular disease (CVD). In insulin resistant states such as the metabolic syndrome, overproduction and impaired clearance of liver-derived very-low-density lipoproteins and gut-derived ...
Priska Stahel, Changting Xiao, Avital Nahmias, Gary F. Lewis   +3 more
doaj   +1 more source

Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity

EMBO Molecular Medicine, 2021
Lipids are the most energy‐dense components of the diet, and their overconsumption promotes obesity and diabetes. Dietary fat content has been linked to the lipid processing activity by the intestine and its overall capacity to absorb triglycerides (TG).
Jonathan Trujillo‐Viera, Rabih El‐Merahbi, Vanessa Schmidt, Till Karwen, Angel Loza‐Valdes, Akim Strohmeyer, Saskia Reuter, Minhee Noh, Magdalena Wit, Izabela Hawro, Sabine Mocek, Christina Fey, Alexander E Mayer, Mona C Löffler, Ilka Wilhelmi, Marco Metzger, Eri Ishikawa, Sho Yamasaki, Monika Rau, Andreas Geier, Mohammed Hankir, Florian Seyfried, Martin Klingenspor, Grzegorz Sumara   +23 more
doaj   +1 more source

VEGFR-3 signaling regulates triglyceride retention and absorption in the intestine [PDF]

, 2018
The lymphatic system transports dietary lipids absorbed and packaged as chylomicrons by enterocytes, for delivery to the bloodstream. Once considered a passive drainage, chylomicron entry into intestinal lymphatic vessels, or lacteals, is now emerging to
Cifarelli, Vincenza, Shew, Trevor, Wolins, Nathan E   +2 more
core   +2 more sources

VLDL receptor mediates the uptake of human chylomicron remnants in vitro.

Journal of Lipid Research, 1996
The VLDL receptor has been described as a new member of the LDL receptor supergene family that specifically binds VLDL in vitro via apolipoprotein E and lipoprotein lipase.
A Niemeier, M Gàfvels, J Heeren, N Meyer, B Angelin, U Beisiegel   +5 more
doaj   +1 more source

Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians.

, 2001
OBJECTIVE: To investigate the association between circulating C-reactive protein (CRP) concentrations and indices of body fat distribution and the insulin resistance syndrome in South Asians and Europeans. DESIGN: : Cross-sectional study.
NG Forouhi, N Sattar, PM McKeigue, PM Ridker, PM Ridker, F Haverkate, W Koenig, MA Mendall, RP Tracy, JC Pickup, JS Yudkin, A Festa, PM McKeigue, PM McKeigue, PM McKeigue, JC Seidell, JR Patsch, J Highton, JP Després, AS Greenberg, T Chajek-Shaul, P Bjorntorp, P Ebeling, U Saxena   +23 more
core   +1 more source

A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) results in altered postprandial chylomicron triglyceride and retinyl palmitate response in normolipidemic carriers.

Journal of Lipid Research, 1996
An Asn291Ser mutation in exon 6 of the lipoprotein lipase gene (LPL) frequently occurs in Caucasians (2-4%) and results in a partial catalytic defect.
S N Pimstone, S M Clee, S E Gagné, L Miao, H Zhang, E A Stein, M R Hayden   +6 more
doaj   +1 more source

Triglyceride-rich lipoproteins prevent septic death in rats. [PDF]

, 1995
Triglyceride-rich lipoproteins bind and inactive bacterial endotoxin in vitro and prevent death when given before a lethal dose of endotoxin in animals.
Calhoun, MC, Feingold, KR, Grunfeld, C, Kane, JP, Kumwenda, ZL, Rapp, JH, Read, TE   +6 more
core  

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Fatty acid esterification and chylomicron formation during fat absorption: 1. Triglycerides and cholesterol esters

Journal of Lipid Research, 1963
Experiments were conducted to study in vivo the over-all fatty acid specificity of the mechanisms involved in chylomicron cholesterol ester and triglyceride formation during fat absorption in the rat. Mixtures containing similar amounts of two, three, or
Arthur Karmen, Malcolm Whyte, DeWitt S. Goodman   +2 more
doaj   +1 more source

Birth outcome in relation to licorice consumption during pregnancy.

, 2001
A role for glucocorticoids is suspected in the etiology of low birth weight. The authors tested whether maternal consumption of glycyrrhizin (an inhibitor of cortisol metabolism) in licorice affects birth weight in humans. A sample of 1,049 Finnish women
Järvenpää, AL, McKeigue, PM, Strandberg, TE, Vanhanen, H   +3 more
core   +1 more source