Results 61 to 70 of about 21,613 (212)

Cell density dependent uptake of chylomicron remnants in rat hepatocyte monolaayers. Effects of compactin and mevalonic acid

, 1987
In rat hepatocytes cultured in lipoprotein-deficient serum, the uptake and degradation of chylomicron remnant cholesteryl ester per mg cell protein varies inversely with cell density.
Jensen, Elmo,, Nilsson, Åke,, Florén, Claes-Henrik,, Lund University.   +3 more
core   +2 more sources

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3770-3777, November 2026.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Delayed chylomicron remnant clearance in subjects with heterozygous familial hypercholesterolaemia.

, 1998
Department of Internal Medicine, University Hospital Utrecht, The Netherlands. MCC.VIGO@wxs.nl OBJECTIVES: To study the role of the LDL receptor in the clearance of chylomicron remnants in humans. DESIGN: Chylomicron remnant clearance was studied in five
Westerveld, G.J., Meijer, E.P., Erkelens, D.W., de Bruin, T.W.A., Cabezas, M.C.   +4 more
core   +1 more source

The pathophysiology of intestinal lipoprotein production

Frontiers in Physiology, 2015
Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that ...
Antonina eGiammanco, Angelo Baldassare Cefalu', Davide eNoto, Maurizio eAverna   +3 more
doaj   +1 more source

Postprandial chylomicrons [PDF]

Journal of Lipid Research, 2004
We examined whether postprandial (PP) chylomicrons (CMs) can serve as vehicles for transporting cholesterol from endogenous cholesterol-rich lipoprotein (LDL+HDL) fractions and cell membranes to the liver via lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP) activities.
Byung-Hong Chung, Ping Liang, Steve Doran, B. H. Simon Cho, Frank Franklin   +4 more
openaire   +2 more sources

Further Insights Into the Mechanisms of Lymph Node Metastasis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson, Meghan J. O'Melia, Kelly C. Rosso, Ian S. Wood, Drishti Lall, Jenny T. Bui   +5 more
wiley   +1 more source

Influence of chylomicron remnants on human monocyte activation in vitro [PDF]

, 2011
Background and aimsAtherosclerosis is known to be an inflammatory disease and there is increasing evidence that chylomicron remnants (CMR), the lipoproteins which carry dietary fats in the blood, cause macrophage foam cell formation and inflammation.
De Pascale, C., Hathaway, N, Bentley, C., F. Bejta, Hathaway, N., De Pascale, C, C.P.D. Wheeler-Jones, Widdows, J, Lawson, C, Bentley, C, Botham, K M, J. Widdows, Botham, K.M., M. Avella, Bejta, F., K.M. Botham, C. De Pascale, C. Lawson, C. Bentley, N. Hathaway, Avella, M A, Wheeler-Jones, C P D, Widdows, J., Bejta, F, Lawson, C., Wheeler-Jones, C.P.D., Avella, M.   +26 more
core   +1 more source

The ddY mouse: a model of postprandial hypertriglyceridemia in response to dietary fat

Journal of Lipid Research, 2012
Postprandial hyperlipidemia (lipemia) is a risk factor for atherosclerosis. However, mouse models of postprandial hyperlipidemia have not been reported. Here, we report that ddY mice display marked postprandial hypertriglyceridemia in response to dietary
Tomomi Yamazaki, Kyoko Kishimoto, Osamu Ezaki   +2 more
doaj   +1 more source

Food Properties, Bioactive Components, and Human Factors as Determinants of Low Nutrient Supply From Foods Can Be Improved With Adequate Nutritional Strategies

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Nutrient adequacy depends on food composition, bioaccessibility, absorption, physiological utilization, dietary access, supply stability, etc. Food properties, human health, agricultural conditions, and socioeconomic barriers influence nutrient delivery.
Chinaza Godswill Awuchi
wiley   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source