Results 81 to 90 of about 21,613 (212)

Sec24C is required for docking the prechylomicron transport vesicle with the Golgi

Journal of Lipid Research, 2010
The rate-limiting step in the transit of dietary fat across the intestinal absorptive cell is its exit from the endoplasmic reticulum (ER) in a specialized ER-to-Golgi transport vesicle, the prechylomicron transport vesicle (PCTV).
Shahzad Siddiqi, Shadab A. Siddiqi, Charles M. Mansbach, II   +2 more
doaj   +1 more source

Identifying Co‐Expressed lncRNAs Correlated With Traits of Interest in an Animal Model for Metabolic Diseases in Humans

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Nutrigenomics investigates how nutrients modulate gene expression. Among them, fatty acids (FA) play important roles in regulating gene transcription, while long non‐coding RNAs (lncRNAs) may be associated with gene regulation and metabolic diseases.
Lucas Echevarria Nascimento, Bruna Pereira Martins da Silva, Camila Sabino de Oliveira, Mariah Castro Durval, Felipe André Oliveira Freitas, Fernanda Nery Ciconello, Izally Carvalho Gervásio, Simara Larissa Fanalli, Pablo Augusto de Souza Fonseca, Beatriz Gutiérrez‐Gil, Vivian Vezzoni de Almeida, Aline Silva Mello Cesar   +11 more
wiley   +1 more source

Genetic factors at the enterocyte level account for variations inintestinal cholesterol absorption efficiency among inbred strains of mice1

Journal of Lipid Research, 2001
Interindividual and interstrain variations in cholesterol absorptionefficiency occur in humans and animals. We investigated physiological biliaryand small intestinal factors that might determine variations in cholesterolabsorption efficiency among inbred
David Q-H. Wang, Beverly Paigen, Martin C. Carey   +2 more
doaj   +1 more source

Chylomicron remnant uptake by enterocytes is receptor dependent

, 1996
During glyceryl trioleate absorption in the rat, mucosal triacylglycerol (TG) fatty acids have been shown to consist of only 71% exogenous oleate. Chylomicron remnants are enriched with endogenous TG fatty acids, compared with their parent chylomicrons,
M. Soued, C. M. Mansbach
core   +1 more source

Determining the Role of Intestinal Basolateral Lipid Substrate Transport (BLST) in Modulating Chylomicron Secretion

, 2019
Chylomicron metabolism plays a critical role in determining plasma levels of triacylglycerols (TAG) and cholesterol, both of which are risk factors for cardiovascular disease.
Li, Diana
core   +1 more source

Degradation of chylomicron remnants by macrophages occurs via phagocytosis

, 1996
Chylomicron remnants bound to rabbit alveolar macrophages with high- affinity (K(d) = 3.3 ± 0.71 μg of protein/mL). The binding of chylomicron remnants was competitively inhibited in the presence of unlabeled remnants and to a lesser extent by ...
Gennat, HC (15495494), Mamo, JCL (15495488), Elsegood, CL (15495491), Yu, Kenny (15495497)   +3 more
core  

Dietary oxidized fatty acids: an atherogenic risk?

Journal of Lipid Research, 2000
Previous studies have suggested that heated fat that contains oxidized fatty acids in the diet might contribute to the presence of oxidized components in circulating lipoproteins.
Meera Penumetcha, Nadya Khan, Sampath Parthasarathy   +2 more
doaj   +1 more source

Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion[S]

Journal of Lipid Research, 2013
Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in metabolism.
Janna A. van Diepen, Rinke Stienstra, Irene O. C.M. Vroegrijk, Sjoerd A.A. van den Berg, Daniela Salvatori, Guido J. Hooiveld, Sander Kersten, Cees J. Tack, Mihai G. Netea, Johannes W.A. Smit, Leo A.B. Joosten, Louis M. Havekes, Ko Willems van Dijk, Patrick C.N. Rensen   +13 more
doaj   +1 more source

Scavenger Receptor BI Plays a Role in Facilitating Chylomicron Metabolism

, 2004
The function of scavenger receptor class B type I (SR-BI) in mediating the selective uptake of high density lipoprotein (HDL) cholesterol esters is well established.
Out, R., Berkel, T.J.C. van, Rensen, P.C.N., Eck, M. van, Vos, P. de, Kruijt, J.K., Hildebrand, R.B.   +6 more
core  

Why Do Men Accumulate Abdominal Visceral Fat?

Frontiers in Physiology, 2019
Men have a higher tendency to accumulate abdominal visceral fat compared to pre-menopausal women. The accumulation of abdominal visceral fat in men, which is a strong independent predictor of mortality, is mainly due to the higher dietary fat uptake by ...
Andromeda M. Nauli, Sahar Matin
doaj   +1 more source