Results 81 to 90 of about 17,950 (189)

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

Dietary oxidized fatty acids: an atherogenic risk?

Journal of Lipid Research, 2000
Previous studies have suggested that heated fat that contains oxidized fatty acids in the diet might contribute to the presence of oxidized components in circulating lipoproteins.
Meera Penumetcha, Nadya Khan, Sampath Parthasarathy   +2 more
doaj   +1 more source

Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion[S]

Journal of Lipid Research, 2013
Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in metabolism.
Janna A. van Diepen, Rinke Stienstra, Irene O. C.M. Vroegrijk, Sjoerd A.A. van den Berg, Daniela Salvatori, Guido J. Hooiveld, Sander Kersten, Cees J. Tack, Mihai G. Netea, Johannes W.A. Smit, Leo A.B. Joosten, Louis M. Havekes, Ko Willems van Dijk, Patrick C.N. Rensen   +13 more
doaj   +1 more source

Why Do Men Accumulate Abdominal Visceral Fat?

Frontiers in Physiology, 2019
Men have a higher tendency to accumulate abdominal visceral fat compared to pre-menopausal women. The accumulation of abdominal visceral fat in men, which is a strong independent predictor of mortality, is mainly due to the higher dietary fat uptake by ...
Andromeda M. Nauli, Sahar Matin
doaj   +1 more source

Fatty acid esterification and chylomicron formation during fat absorption in rat: III. Positional relations in triglycerides and lecithin

Journal of Lipid Research, 1965
Chylomicron triglyceride and lecithin obtained after feeding mixtures of three or four free fatty acids to rats were hydrolyzed using pancreatic lipase and phospholipase A respectively.
Malcolm Whyte, DeWitt S. Goodman, Arthur Karmen   +2 more
doaj   +1 more source

Volanesorsen in the Treatment of Familial Chylomicronemia Syndrome or Hypertriglyceridaemia: Design, Development and Place in Therapy

Drug Design, Development and Therapy, 2020
Oluwayemisi Esan, Anthony S Wierzbicki Department of Metabolic Medicine/Chemical Pathology, Guy’s & St Thomas’ Hospitals, London SE1 7EH, UKCorrespondence: Anthony S WierzbickiDepartment of Chemical Pathology, St.
Esan O, Wierzbicki AS
doaj  

The intracellular chylomicron highway: novel insights into chylomicron biosynthesis, trafficking, and secretion

Current Opinion in Lipidology
Purpose of review Chylomicron biosynthesis plays a vital role in supplying essential lipids and lipid soluble vitamins to peripheral tissues for various functions. Despite this, the intracellular synthesis, trafficking, and secretion of chylomicrons remains only partly understood.
Visser, Ankia, Hussain, M. Mahmood, Kuivenhoven, Jan Albert   +2 more
openaire   +2 more sources

Editorial: The Role of the Lymphatic System in Lipid and Energy Metabolism, and Immune Homeostasis During Obesity and Diabetes

Frontiers in Physiology, 2021
Vincenza Cifarelli, Hong Chen, Joshua P. Scallan   +2 more
doaj   +1 more source

[Chylomicron metabolism].

Revista do Hospital das Clinicas, 1990
The liver is known to play a central role in the chylomicron metabolism. It synthesizes apolipoproteins (e.g., apo A I, apo C II, apo E), lecithin cholesterol acyltransferase, hepatic lipase and is responsible for the chylomicron remnant removal. Not surprisingly then the chylomicron metabolism is compromised in liver diseases such as acute hepatitis ...
A O, Damião, A M, Sipahi e, E C, Quintão   +2 more
openaire   +1 more source

GPR182 and the reframing of lacteal chylomicron uptake. [PDF]

J Clin Invest
Yu L.
europepmc   +1 more source