Results 21 to 30 of about 226,527 (234)

Understanding the abnormal thermal behavior of nanofluids through infrared thermography and thermo-physical characterization

open access: yesScientific Reports, 2021
Nanofluids (NFs) are colloidal suspensions of nanoparticles (NPs) within a base fluid. Unlike conventional mixtures, NFs exhibit dramatically enhanced properties, such as an abnormal increase in heat capacity at low concentration of NPs (e.g., Cp values ...
Adela Svobodova-Sedlackova   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

La importància de l'anàlisi històrica de les imatges de la ciència, amb Nick Hopwood [PDF]

open access: yes, 2011
La Història de la Ciència ha mostrat una tendència tradicional a l'estudi dels textos oblidant-se de les imatges. Però la pràctica científica produeix una àmplia varietat de representacions visuals i el seu estudi ofereix una excel·lent base per ...
Florensa, Clara, Hopwood, Nick
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

From night bustle to printed quietness [PDF]

open access: yes, 2001
Des del punt de vista d'un científic, la comunicació científica entre col·legues significa la possibilitat de reconeixement dels postulats que es desprenen de la seva recerca, és la ciència de dia, la quietud de la ciència impresa.
Jacob, François
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

La ficció com a eina docent en l’àmbit de les ciències i la tecnologia [PDF]

open access: yes, 2012
La motivació de l’alumnat és la fita a aconseguir avui en dia, en un món cada cop més canviant sobretot propiciat pels avenços tecnològics i científics. Per tal de despertar l´interès per aquestes matèries incloses en el pla d’estudi actual dintre de l´
Martín Gallardo, Rubén
core   +1 more source

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