Results 31 to 40 of about 224,064 (235)
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
"Cultura, societat i política són part consubstancial que defineix què són i com són la ciència i la tecnologia a cada moment històric i en cada lloc del món" [PDF]
, 2016 Jaume Sastre-Juan, investigador post-doctoral al Centro Interuniversitário de História das Ciências e da Tecnologia - Universidade de Lisboa va impartir una xerrada a Barcelona, titulada "La innocència de prémer un botó: algunes claus per a una història ...
Gil Farrero, Judit
core +1 more source
Els "Vespres científics" de l'Escola Pia [PDF]
, 2005 Des de fa vuit anys, pares, alumnes, ex-alumnes i professors ens trobem alguns dies al vespre per fer ciència a l'abast de tothom. A més de gaudir de la ciència, aquesta activitat ens ha permès conèixer persones molt diverses, compartir experiències amb ...
Segura, Marta, Valls, Josep M.
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
La ciència, la filosofia i l’art. Nota sobre «¿Què ens fa humans?», de Salvador Macip (2022)
Enrahonar: Quaderns de FilosofiaAl llibre ¿Què ens fa humans? (2022), Salvador Macip explora la pregunta del títol a través d’un diàleg fructífer entre la ciència i la filosofia. Ara bé, Macip diu que no està interessat en tota la filosofia, sinó només en «la part de la filosofia que ...
Ignasi Llobera
doaj +1 more source
ASSOCIATE EDITORS AND REVIEWERS AD HOC
Ciência Florestal, 2013 -
Ciência Florestal
doaj +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Social movements in sustainability transitions : identity, social learning & power in the Spanish & Turkish water domains / [PDF]
, 2010 Descripció del recurs: el 02 de novembre de 2010Dominant economic growth and nation-state building practices are often based on detaching individuals from other individuals and communities from their natural environment in which their livelihoods used to
Ilhan, Akgün +1 more
core +1 more source
Canvi de rumb en filosofia de la ciència [PDF]
, 1995 El segle XX apareix filosòficament com un segle de gran dispersió i multiplicitat. Tanmatix, aquesta es pot reduir dràsticament: irracionalisme, sociologia i filosofia social, lògica i metodologia.
Ros i Bosch, Àngel
core +3 more sources
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source