Results 21 to 30 of about 21,720 (183)

Assessment of the gene mosaicism burden in blood and its implications for immune disorders

open access: yesScientific Reports, 2021
There are increasing evidences showing the contribution of somatic genetic variants to non-cancer diseases. However, their detection using massive parallel sequencing methods still has important limitations.
Manuel Solís-Moruno   +7 more
doaj   +1 more source

Interventions across the retirement transition for improving well-being: a scoping review protocol

open access: yesBMJ Open, 2019
Introduction The work-to-retirement transition involves a process of psychologically and behaviourally distancing oneself from the workforce that is often accompanied by other social changes.
Miriam Rodríguez-Monforte   +7 more
doaj   +1 more source

Benestar emocional, qualitat de vida i resiliència en l’alumnat universitari: un estudi comparatiu entre variables sociodemogràfiques i acadèmiques

open access: yesRevista d'Innovació i Recerca en Educació
INTRODUCCIÓ. L’inici de la universitat és una etapa de canvis i exigències que pot augmentar la vulnerabilitat de l’alumnat als problemes de salut mental, fent que factors com la resiliència, la satisfacció vital, la qualitat de vida i l’esgotament ...
Cristina Cañete-Massé   +4 more
doaj   +1 more source

The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells

open access: yesOncogenesis, 2021
Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was
Sonia Núñez-Vázquez   +9 more
doaj   +1 more source

Obesity-promoting factors in Mexican children and adolescents: challenges and opportunities [PDF]

open access: yesGlobal Health Action, 2016
Background: Mexico is a developing country with one of the highest youth obesity rates worldwide; >34% of children and adolescents between 5 and 19 years of age are overweight or obese.
Magaly Aceves-Martins   +4 more
doaj   +1 more source

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

open access: yesFrontiers in Molecular Neuroscience, 2017
The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system.
Erica Hurtado   +11 more
doaj   +1 more source

The “Healthy Meals” web app for the assessment of nutritional content and food allergens in restaurant meals: Development, evaluation and validation

open access: yesDigital Health, 2022
Objective The development and the evaluation of the Healthy Meals web app designed for professionals from different disciplines related to food, aimed to assess the nutritional and food allergen content of restaurant meals, was described.
Floriana Mandracchia   +4 more
doaj   +1 more source

Intervenció en psicologia clínica i de la salut (IPCyS) [PDF]

open access: yes, 2013
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445 ...
Arcos, M. (Maria del Mar)   +5 more
core  

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia   +7 more
wiley   +1 more source

Membrane Receptor-Induced Changes of the Protein Kinases A and C Activity May Play a Leading Role in Promoting Developmental Synapse Elimination at the Neuromuscular Junction

open access: yesFrontiers in Molecular Neuroscience, 2017
Synapses that are overproduced during histogenesis in the nervous system are eventually lost and connectivity is refined. Membrane receptor signaling leads to activity-dependent mutual influence and competition between axons directly or with the ...
Josep M. Tomàs   +7 more
doaj   +1 more source

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