Results 31 to 40 of about 1,882,868 (239)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Structural analysis of magnetic nanocomposites based on chitosan [PDF]

open access: yes, 2018
This work investigates the structure and magnetic properties of chitosan based films with different contents of magnetic nanoparticles (MNPs) of around 10 nm as well as the effects of the addition of glycerol as plasticizer.
Kloster, Gianina Andrea   +5 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CMOS mixed-signal MODEM for data transmission and control of electrical household appliances using the low-voltage power-line [PDF]

open access: yes, 2003
This paper presents a CMOS 0.6μm mixed-signal MODEM ASIC for data transmission using the low-voltage power line. This circuit includes all the analog blocks needed for input interfacing and modulation/demodulation (PLL-based frequency synthesis, slave ...
Domínguez Matas, Carlos   +4 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

On the development of a MODEM for data transmission and control of electrical household appliances using the low-voltage power-line [PDF]

open access: yes, 2003
This paper presents a CMOS 0,6μm mixed-signal MODEM ASIC for data transmission on the low-voltage power line. The circuit includes all the analog circuitry needed for input interfacing and modulation/demodulation (PLL-based frequency synthesis, slave ...
Domínguez Matas, Carlos   +4 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Totally umbilical disks and applications to surfaces in three-dimensional homogeneous spaces [PDF]

open access: yes, 2008
Following [Ch] and [dCF], we give sufficient conditions for a disk type surface, with piecewise smooth boundary, to be totally umbilical for a given Coddazi pair.
Espinar, José M.   +1 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Improving NDT with Automatic Test Case Generation [PDF]

open access: yes, 2013
The model-driven development defi nes the software development process as a set of iterations to create models and a set of transformations to obtain new models. From this point of view, this paper presents the enhancement of a model- driven approach,
Cutilla, C. R.   +4 more
core   +1 more source

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