Results 31 to 40 of about 1,862,700 (239)

Totally umbilical disks and applications to surfaces in three-dimensional homogeneous spaces [PDF]

open access: yes, 2008
Following [Ch] and [dCF], we give sufficient conditions for a disk type surface, with piecewise smooth boundary, to be totally umbilical for a given Coddazi pair.
Espinar, José M.   +1 more
core  

Structural analysis of magnetic nanocomposites based on chitosan [PDF]

open access: yes, 2018
This work investigates the structure and magnetic properties of chitosan based films with different contents of magnetic nanoparticles (MNPs) of around 10 nm as well as the effects of the addition of glycerol as plasticizer.
Kloster, Gianina Andrea   +5 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Characterisation of PVD-TiN coated austempered ductile iron: Effects of nodule count and austempering temperature [PDF]

open access: yes, 2011
In this work PVD-TiN coatings are deposited on ADI substrates austempered at 280 and 360°C, with nodule counts varying between 490 and 1 100 nod/mm2. The deposition is performed at 300°C by the arc ion plating technique.
Colombo, Diego Alejandro   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates [PDF]

open access: yes, 2013
Antibiotic resistance is one of the main problems concerning public health or clinical practice. Antimicrobial peptides appear as good candidates for the development of new therapeutic drugs.
Corso, Alejandra   +7 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

On the development of a MODEM for data transmission and control of electrical household appliances using the low-voltage power-line [PDF]

open access: yes, 2003
This paper presents a CMOS 0,6μm mixed-signal MODEM ASIC for data transmission on the low-voltage power line. The circuit includes all the analog circuitry needed for input interfacing and modulation/demodulation (PLL-based frequency synthesis, slave ...
Domínguez Matas, Carlos   +4 more
core   +1 more source

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