Results 31 to 40 of about 46,684 (177)
Toxicología general y aplicada [PDF]
La toxicología es una ciencia en constante construcción. Desde sus inicios como ciencia ha estudiado las interacciones químicas y biológicas que ocurren entre los seres vivos y los xenobióticos o sustancias químicas ajenas al organismo que resultan en ...
Giannuzzi, Leda
core +1 more source
Oxoisoaporphines and Aporphines: Versatile Molecules with Anticancer Effects
Cancer is a disease that involves impaired genome stability with a high mortality index globally. Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity.
Esteban Rodríguez-Arce +4 more
doaj +1 more source
The high prevalence of nosocomial infections is related to the use of medical insertion devices such as central venous catheters (CVCs). Most of the microorganisms causing nosocomial infections are biofilm producers, this characteristic allows them to ...
Sandra Pamela Cangui-Panchi +5 more
doaj +1 more source
Battle royale: Immune response on biofilms – host-pathogen interactions
The research interest of the scientific community in biofilm-forming microorganisms is growing due to the problems caused by their infections affecting humans and animals, mainly because of the difficulty of the host immune system in eradicating these ...
Sandra Pamela Cangui-Panchi +6 more
doaj +1 more source
New Drug Design Avenues Targeting Alzheimer’s Disease by Pharmacoinformatics-Aided Tools
Neurodegenerative diseases (NDD) have been of great interest to scientists for a long time due to their multifactorial character. Among these pathologies, Alzheimer’s disease (AD) is of special relevance, and despite the existence of approved drugs for ...
Lily Arrué +15 more
doaj +1 more source
ABSTRACT Flavonoids are natural secondary metabolites of plants with a basic composition derived from polyphenols that can produce a plethora of different neurophysiological effects, some of which are relevant to anxiety disorders. As such, many flavonoids have been evaluated in behavioral screens in preclinical research on anxiolytics.
Jhennify Albuquerque Machado +7 more
wiley +1 more source
Dysphania ambrosioides is a widely distributed species with a traditional use in folk medicine, but it exhibits marked chemical variability that limits its standardization.
Susana Blacio +5 more
doaj +1 more source
Algevir: An Expression System for Microalgae Based on Viral Vectors
The use of recombinant algae for the production of valuable compounds is opening promising biotechnological applications. However, the development of efficient expression approaches is still needed to expand the exploitation of microalgae in ...
Bernardo Bañuelos-Hernández +7 more
doaj +1 more source
Investigar para transformar [PDF]
La Universidad Andrés Bello ha definido su misión, orientándola para brindar a quienes aspiren a progresar, la posibilidad de una educación de calidad, integradora e inserta en un mundo global.
Universidad Andrés Bello
core
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez +10 more
wiley +1 more source

