PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF [PDF]
, 2019 We showed that Parathyroid Hormone-related Peptide (PTHrP) induces proliferation, migration, survival and chemoresistance via MAPKs and PI3K/AKT pathways in colorectal cancer (CRC) cells.
Calvo, Natalia Graciela +4 more
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Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines [PDF]
, 2019 Soluble guanylyl cyclase (sGC) is a heterodimeric enzyme constituted by two subunits, α1 and β1. Previously we have shown that 17β-estradiol (E2) exerts opposite effects on these subunits by increasing α1 and decreasing both β1 expression and enzymatic ...
Bollani, Sabrina Natalia +6 more
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Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells [PDF]
, 2010 Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related death worldwide. Current treatments are extremely disappointing.
Alaniz, Laura Daniela +8 more
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Biological evaluation and molecular modelling of didanosine derivatives [PDF]
, 2014 Five carbonate derivatives of 50-O-20,30-dideoxyinosine (DDI, 1) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV activity and cytotoxicity being evaluated afterward in human peripheral blood mononuclear cells ...
Briñon, Margarita Cristina +6 more
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Effects of Ingestion of Lithic Particles on Growth of the Apple Snail Pomacea canaliculata (Caenogastropoda, Ampullariidae) [PDF]
, 2016 Lithic particles are a common feature in the digestive tract of freshwater snails. Their role in the digestive processes has been demonstrated in some microphytophagous and detritivorous species, as they enhance growth, assimilation and reproduction.
Manara, Enzo +2 more
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Senecio bonariensis Hook. & Arn. promising arsenic phytoextractor from water in laboratory and field trials [PDF]
, 2019 The use of plant species to cleanse groundwater with excessive concentrations of arsenic (As) derived from contact with weathered materials has become a valuable option to treat it.
Cambi, Viviana Nora +6 more
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Photo-damage, photo-protection and age-related macular degeneration [PDF]
, 2015 Age-related macular degeneration (AMD) is a degenerative retinal disease that causes blindness in people 60-65 years and older, with the highest prevalence appearing in people 90 years-old or more.
Marquioni Ramella, Melisa Daniela +1 more
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Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]
, 2014 Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo +3 more
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Prolactin and its receptor as therapeutic targets in glioblastoma multiforme [PDF]
, 2019 Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis.
Abt, Araceli +13 more
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Self-fluorescent antibiotic MoOx–hydroxyapatite: a nano-theranostic platform for bone infection therapies [PDF]
, 2019 Nowadays, the repair of large-size bone defects represents a huge medical challenge. A line of attack is the construction of advanced biomaterials having multifunctional properties.
Baldini, Monica Diana +6 more
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