Results 41 to 50 of about 223,204 (307)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential of science to address the hunger issue: Ecology, biotechnology, cattle breeding and the large pantry of the sea

Journal of Innovation & Knowledge, 2018
The knowledge about the real possibilities that current science gives us is basic to support everything that is not negative either for men or for our environment.
José Tena Medialdea, Jesús A. Prieto Ruiz, Carmen Fagoaga García, Antonio Calvo Capilla, Jerónimo Chirivella Martorell, Joel Bueso Rodenas   +5 more
doaj   +1 more source

Didáctica de las Ciencias Experimentales

Revista de Educación en Biología, 2005
Libro: Dirección: Francisco Perales Palacios y Pedro Cañal de León. Editorial.
openaire   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A Study of the Usefulness of Physical Models and Digital Models for Teaching Science to Prospective Primary School Teachers

Education Sciences, 2023
This study focuses on the impact of the use of teaching resources on future teachers in different formats, physical and digital. We worked with a single task dealing with nutrition in humans with two groups of students, but one group worked with a ...
F. Javier Robles-Moral, Manuel Fernández-Díaz, Gabriel Enrique Ayuso-Fernández   +2 more
doaj   +1 more source

Edición de videos digitales en la formación del profesorado [PDF]

, 2009
Las nuevas tecnologías están cada vez más presentes en la enseñanza de las Ciencias Experimentales y en la formación del profesorado de Ciencias Experimentales de diferentes niveles educativos. Es por ello, por lo que se ha considerado necesario trabajar
Etxabe Urbieta, J.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

XXV Encuentro de Didáctica de las Ciencias Experimentales

Revista Eureka sobre enseñanza y divulgación de las ciencias, 2013
2 ...
  +6 more sources

Evolución de las competencias científicas en las carreras de Bioquímica y Biotecnología de la Universidad Nacional del Litoral, Argentina. Un estudio longitudinal

Enseñanza de las Ciencias, 2015
Este estudio está fundamentado en el marco de las pruebas PISA 2006 (OCDE, 2008), sobre competencia científica. En la presente tesis se indagó en qué medida una muestra de alumnos de las carreras de Bioquímica y Biotecnología de la Universidad Nacional ...
Claudia Beatriz Falicoff
doaj