Results 51 to 60 of about 299,896 (192)

Small bowel transplantation in rats, a multicenter experience summarizing the pitfalls to be overcome [PDF]

, 2016
Small Bowel transplantation in rats is a highly complex microsurgical procedure because several technical complications may lead to recipient mortality and transplant failure. Our aim was to report the most common complications associated with orthotopic
Abate, Juan C., Andrés Moreno, Ane M., Gondolesi, Gabriel Eduardo, Hernández Oliveros, Francisco, Lausada, Natalia Raquel, Navarro Zorraquino, Marta, Pastor Oliver, Cristina, Rumbo, Martín, Stringa, Pablo Luis, Vecchio, Leandro   +9 more
core   +2 more sources

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Freely Available Tool (FAT) for automated quantification of lipid droplets in stained cells [PDF]

, 2017
In this study, wepropose an automatic procedure for digital image processing. Wedescribe a method that can efficiently quantify and characterizelipid droplets distributions in different cell types in culture.Prospectively, the lipid droplets detection ...
Bustos, Diego Martin, del Veliz, Samanta, Frontini López, Yesica Romina, Gojanovich, Aldana Daniela, Masone, Diego Fernando, Uhart, Marina   +5 more
core  

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Profesor Doctor Jorge Bacallao Gallestey: Excelencia en la aplicación de métodos cuantitativos en Ciencias Médicas.

Revista Habanera de Ciencias Médicas, 2014
Jorge Bacallao Gallestey nació en La Habana donde cursó la enseñanza primaria, secundaria y la carrera de Matemáticas en la Universidad de La Habana. Comenzó su vida laboral  en 1973 en la antigua Facultad de Ciencias Médicas de la Universidad de La ...
Nerys González García, Fidel Cathcart Roca   +1 more
doaj  

La estimulación gabaérgica del núcleo septal lateral del cerebro de ratas macho incrementa la respuesta agresiva frente a estímulos neutros [PDF]

, 2009
El núcleo septal lateral forma parte de estructuras subcorticales del cerebro. La destrucción de dicho núcleo genera lo que se conoce como síndrome de furia septal.
Bazzocchini, Vanesa, Cabrera, Ricardo, Casas, Sebastián, Escudero, Carla, Giuliani, Fernando, Laconi, Miriam, Nanfaro, Federico, Vega, Adriana, Yunes, Roberto   +8 more
core  

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

Comparación de diferentes parámetros de evaluación en sujetos con asma moderada estable sin exacerbación microbiana, tratados con Salmeterol-Fluticasona vs Ciclesonida y Salbutamol a demanda [PDF]

, 2009
El asma es una entidad clínica caracterizada por la combinación de tres factores: obstrucción de la vía aérea con reversibilidad espontánea y/o farmacológica, hiperrreactividad bronquial e inflamación local.
Elías, P., Fazio, C., Garófoli, A., Molina, A., Montbrun, M., Montoya, P., Sagua, M., Telechea, A., Yunes, Roberto   +8 more
core  

University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students

Clinical Endocrinology, EarlyView.
ABSTRACT Background University exams are recognised as naturalistic stressors that may elicit psychosocial and physiological responses in students. This pilot study investigated the short‐ and long‐term effects of exam‐related stress on hypothalamic–pituitary–adrenal (HPA) axis activity, focusing on cortisol production and rhythmicity.
Filipy Borghi, Priscila Cristina da Silva, Elisângela Farias‐Silva, Fernando Canova, Aglecio Luiz Souza, Aline Barbedo Arouca, Dora Maria Grassi   +6 more
wiley   +1 more source