Results 51 to 60 of about 273,070 (210)

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Ectopic and molar pregnancies in Brazil: A secondary analysis of the WHO multi‐country survey on abortion

International Journal of Gynecology &Obstetrics, EarlyView.
Luís Henrique Leão, Camila Ayume Amano Cavalari, Luiz Francisco Baccaro   +2 more
wiley   +1 more source

Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components

Alimentary Pharmacology &Therapeutics, EarlyView.
The Lyon and Milan scores outperformed AET and DeMeester score in predicting outcomes in GERD patients. When concordant, they provide optimal predictive accuracy, guiding escalation of therapy. ABSTRACT Background Confidence in gastro‐oesophageal reflux disease (GERD) diagnosis is crucial to improve outcomes from escalation of treatment. The Lyon score
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Sara Boveri, Benjamin D. Rogers, Nicola De Bortoli, Anthony Hobson, Brian E. Louie, Yeong Yeh Lee, Salvatore Tolone, Elisa Marabotto, Jordan Haworth, Megan L. Ivy, Lorenzo Cusmai, Edoardo Campioli, Dimitrios Theodorou, Tania Triantafyllou, Andrea Pasta, Francesco Calabrese, Vincent Tee, Daniele Bernardi, Carlo Galdino Riva, Roberta De Maron, Enrique Coss‐Adame, Amit Patel, Emanuele Asti, Edoardo Savarino, C. Prakash Gyawali   +27 more
wiley   +1 more source

Monovalent glycoconjugates of sulforaphane prevent inflammation induced by lipopolysaccharide in human dendritic cells by inhibiting NF‐ĸB signalling pathway

British Journal of Pharmacology, EarlyView.
Background and Purpose Sulforaphane (SFN) has notable health benefits but faces challenges due to its poor solubility and delivery. This study investigates SFN‐glycoconjugates effects on lipopolysaccharide (LPS)‐induced inflammation in dendritic cells (DCs). With the aiming to enhance their therapeutic potential against inflammatory diseases.
Camila Leiva‐Castro, Ana Maria Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana Teresa Carmona, Soledad López‐Enríquez, Francisca Palomares   +5 more
wiley   +1 more source

La conciencia : sus límites y sus patologías [PDF]

, 2009
Fil: Nazar, Jorge. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Área de PsiquiatríaFil: Nazar, Ana Clara. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas.
Nazar, Ana Clara, Nazar, Jorge
core  

Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Optimal treatment for frontal fibrosing alopecia (FFA) remains contentious. An international expert panel agreed that highly/ultra‐potent topical steroids were the preferred first‐line topical therapy. Preferred systemic therapies were 5‐alpha reductase inhibitors, followed by hydroxychloroquine.
Nekma Meah, Jane Li, Dmitri Wall, Katherine York, Bevin Bhoyrul, Laita Bokhari, Lachlan Coulthard, Leila Asfour, Leonardo Spagnol Abraham, Daniel Asz‐Sigall, Wilma F. Bergfeld, Regina C. Betz, Ulrike Blume‐Peytavi, Valerie Callender, Vijaya Chitreddy, Andrea Combalia, George Cotsarelis, Brittany Craiglow, Rachita Dhurat, Ncoza Dlova, Jeff Donovan, Andrei Doroshkevich, Samantha Eisman, Paul Farrant, Aida Gadzhigoroeva, Jack Green, Ramon Grimalt, Matthew Harries, Maria Hordinsky, Alan D. Irvine, Victoria Jolliffe, Spartak Kaiumov, Brett King, Steven Kossard, Joyce Lee, Won‐Soo Lee, Nino Lortkipanidze, Amy McMichael, Natasha Atanaskova Mesinkovska, Andrew Messenger, Paradi Mirmirani, Elise Olsen, Seth J. Orlow, Yuliya Ovcharenko, Bianca Maria Piraccini, Rodrigo Pirmez, Adriana Rakowska, Pascal Reygagne, Janet Roberts, Lidia Rudnicka, David Saceda‐Corralo, Jerry Shapiro, Pooja Sharma, Tatiana Silyuk, Poonkiat Suchonwanit, Anita Takwale, Antonella Tosti, W. I. Visser, Sergio Vañó‐Galván, Annika Vogt, Martin Wade, Leona Yip, Abraham Zlotogorski, Cheng Zhou, Rodney Sinclair   +64 more
wiley   +1 more source

Comparación de diferentes parámetros de evaluación en sujetos con asma moderada estable sin exacerbación microbiana, tratados con Salmeterol-Fluticasona vs Ciclesonida y Salbutamol a demanda [PDF]

, 2009
El asma es una entidad clínica caracterizada por la combinación de tres factores: obstrucción de la vía aérea con reversibilidad espontánea y/o farmacológica, hiperrreactividad bronquial e inflamación local.
Elías, P., Fazio, C., Garófoli, A., Molina, A., Montbrun, M., Montoya, P., Sagua, M., Telechea, A., Yunes, Roberto   +8 more
core  

Automated identification of spotted‐fever tick vectors using convolutional neural networks

Medical and Veterinary Entomology, EarlyView.
We evaluate the performance of convolutional neural networks (CNN) AlexNet, ResNet‐50 and MobileNetV2 for the automated identification of tick species capable of transmitting spotted fever. CNNs achieved accuracy rates of ~90% in identifying ticks and showed sensitivities of 59%–100% according to species, sex, position or image resolution.
Isadora R. C. Gomes, Vinícius L. Miranda, José Fabrício C. Leal, Igor P. Oliveira, Paula J. Silva, Karla Bitencourth, Claudio M. Rodrigues, Liege R. Siqueira, Marcelo B. Labruna, Gilberto S. Gazeta, Marinete Amorim, Rodrigo Gurgel‐Gonçalves   +11 more
wiley   +1 more source

La estimulación gabaérgica del núcleo septal lateral del cerebro de ratas macho incrementa la respuesta agresiva frente a estímulos neutros [PDF]

, 2009
El núcleo septal lateral forma parte de estructuras subcorticales del cerebro. La destrucción de dicho núcleo genera lo que se conoce como síndrome de furia septal.
Bazzocchini, Vanesa, Cabrera, Ricardo, Casas, Sebastián, Escudero, Carla, Giuliani, Fernando, Laconi, Miriam, Nanfaro, Federico, Vega, Adriana, Yunes, Roberto   +8 more
core  

Freely Available Tool (FAT) for automated quantification of lipid droplets in stained cells [PDF]

, 2017
In this study, wepropose an automatic procedure for digital image processing. Wedescribe a method that can efficiently quantify and characterizelipid droplets distributions in different cell types in culture.Prospectively, the lipid droplets detection ...
Bustos, Diego Martin, del Veliz, Samanta, Frontini López, Yesica Romina, Gojanovich, Aldana Daniela, Masone, Diego Fernando, Uhart, Marina   +5 more
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